Detailed information NTG0261123

Bioinformatically predicted

Overview

• Name: micB
• Type: Regulator
• Locus tag: CRH08_RS08330
• Genome accession: NZ_CP025419
• Coordinates: 1603617..1604966 (-)
• Length: 449 a.a.
• NCBI ID: WP_009910235.1
• Uniprot ID: A0A0Z8DHB7
• Organism: Streptococcus suis strain SH0104
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1598617..1609966

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CRH08_RS08310	-	1600174..1600629 (-)	456	WP_002935846.1	ATP-binding cassette domain-containing protein	-
CRH08_RS08315	-	1600868..1602070 (+)	1203	Protein_1573	IS110 family transposase	-
CRH08_RS08325	vicX	1602807..1603610 (-)	804	WP_009910233.1	MBL fold metallo-hydrolase	Regulator
CRH08_RS08330	micB	1603617..1604966 (-)	1350	WP_009910235.1	cell wall metabolism sensor histidine kinase VicK	Regulator
CRH08_RS08335	micA	1604959..1605663 (-)	705	WP_004298854.1	response regulator YycF	Regulator
CRH08_RS08340	-	1605857..1606618 (+)	762	WP_002935839.1	amino acid ABC transporter ATP-binding protein	-
CRH08_RS08345	-	1606629..1607468 (+)	840	WP_002935837.1	transporter substrate-binding domain-containing protein	-
CRH08_RS08350	-	1607483..1608181 (+)	699	WP_013730248.1	amino acid ABC transporter permease	-
CRH08_RS08355	-	1608196..1608855 (+)	660	WP_009910247.1	amino acid ABC transporter permease	-

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 51099.13 Da
• Isoelectric Point: 4.5202

>NTDB_id=261123 CRH08_RS08330 WP_009910235.1 1603617..1604966(-) (micB) [Streptococcus suis strain SH0104]
MINQLRYLMTTAEFWFVVILIGFLIALTVLLIENYRDNKQIKQLNQKVNALIEGNYADVLDMRGSPEITDMANSLNDLSE
VIRLTHDNLEQEKTRLTSILSYMSDGVIATDRIGRIIMINDMAQKQLGLSSQKQEQYHLLEVLDLSDRYTLRDLLAQTPE
IVIDHTNENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGQIDVELINFTAFVTFILNRFDQMKNTDSDKVYTIVRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGTITFSMKTTDSQLIVSVSDEGLGIPKTDLPRIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSKDIALDEWDDSDEEE

Nucleotide

• Length: 1350 bp

>NTDB_id=261123 CRH08_RS08330 WP_009910235.1 1603617..1604966(-) (micB) [Streptococcus suis strain SH0104]
ATGATTAATCAATTACGTTATTTAATGACCACGGCAGAATTTTGGTTTGTTGTCATTTTGATTGGCTTTCTAATTGCTCT
GACGGTCCTTTTGATTGAAAACTATCGGGATAATAAGCAAATTAAACAACTCAATCAAAAAGTCAATGCCTTAATTGAGG
GGAATTATGCAGATGTGTTAGACATGAGGGGAAGTCCTGAAATCACAGATATGGCGAATTCTCTTAATGATCTGTCCGAA
GTCATCCGCTTAACTCATGATAATTTAGAACAAGAAAAGACGCGTCTGACTTCCATCCTGTCCTATATGAGTGACGGTGT
TATTGCTACAGACCGTATCGGACGGATCATCATGATTAACGATATGGCCCAGAAACAGTTGGGGCTTTCTAGCCAAAAGC
AGGAGCAGTATCACCTGCTCGAGGTTTTAGATTTATCAGACCGTTATACATTGAGAGATTTGTTGGCTCAGACACCTGAG
ATTGTGATTGATCACACCAATGAAAACGAAGAATTTTTGACTTTACGTGCTAATTTTGCCACGATTCGTAGTGAGAGTGG
CCTGATTTCTGGCTTGGTAGTCGTCTTGCATGATATGACCGAGCAGGCCAAGGAAGAACGGGAACGTAGGCTGTTTGTGT
CAAATGTGAGTCATGAATTGCGTACGCCATTGACTTCCGTTAAATCCTATCTAGAGGCTCTGGATGAGGGGGCGCTGACG
GAGTCTGTTGCACCGAGTTTTGTTAAGGTATCCTTAGATGAGACCAACCGCATGATGCGGATGATTACAGACCTCCTAAG
CTTATCGCGTATTGATAATCAAGTTGGTCAGATAGATGTTGAACTGATAAACTTTACTGCTTTTGTGACCTTTATTCTTA
ACCGTTTTGACCAAATGAAAAATACTGATTCTGATAAGGTCTATACGATTGTTCGTGACTATCAAATCAGTCCTATTTGG
GTTGAGATTGATACAGATAAGATGACTCAGGTTTTAGATAATATCTTAAATAATGCCATTAAATATTCGCCAGATGGCGG
GACAATTACCTTCAGCATGAAGACCACAGATAGCCAGTTGATTGTATCCGTATCAGACGAAGGTCTGGGGATTCCGAAAA
CAGATTTACCTAGAATTTTTGACCGATTTTATCGCGTAGACAAGGCACGATCTCGTGCCCAAGGCGGTACAGGTCTTGGT
TTAGCTATTGCAAAAGAAATCGTGAAACAACATAAGGGCTTTATCTGGGCTAAAAGCGAATATGGTCATGGCTCAACGTT
TACAATTGTCTTGCCGTACAGCAAGGACATCGCACTGGATGAGTGGGATGATTCAGATGAGGAAGAATAG

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (324-434)

• PAS fold (PAS) (96-199)

3D structure

• AlphaFold DB: A0A0Z8DHB7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micB	Streptococcus pneumoniae Cp1015	70.183	97.105	0.682
vicK	Streptococcus mutans UA159	70.72	89.755	0.635