Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CWE28_RS09070 Genome accession   NZ_CP030861
Coordinates   1840579..1841223 (+) Length   214 a.a.
NCBI ID   WP_003085214.1    Uniprot ID   A0A0H2ZLY6
Organism   Pseudomonas aeruginosa strain HS9     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1835579..1846223
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CWE28_RS09045 (CWE28_09040) - 1836071..1837552 (-) 1482 WP_003121853.1 AAA family ATPase -
  CWE28_RS09050 (CWE28_09045) - 1837631..1837969 (+) 339 WP_003085225.1 histidine triad nucleotide-binding protein -
  CWE28_RS09055 (CWE28_09050) coq7 1838069..1838716 (+) 648 WP_003085224.1 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone monooxygenase -
  CWE28_RS09060 (CWE28_09055) speD 1838771..1839565 (-) 795 WP_003085223.1 adenosylmethionine decarboxylase -
  CWE28_RS09065 (CWE28_09060) - 1839885..1840307 (-) 423 WP_023114712.1 OsmC family protein -
  CWE28_RS09070 (CWE28_09065) crp 1840579..1841223 (+) 645 WP_003085214.1 cAMP-activated global transcriptional regulator CRP Regulator
  CWE28_RS09075 (CWE28_09070) trpC 1841285..1842121 (-) 837 WP_003085205.1 indole-3-glycerol phosphate synthase TrpC -
  CWE28_RS09080 (CWE28_09075) trpD 1842118..1843167 (-) 1050 WP_003085203.1 anthranilate phosphoribosyltransferase -
  CWE28_RS09085 (CWE28_09080) - 1843169..1843774 (-) 606 WP_003117978.1 aminodeoxychorismate/anthranilate synthase component II -
  CWE28_RS09090 (CWE28_09085) - 1844193..1844423 (-) 231 WP_003118930.1 hypothetical protein -
  CWE28_RS09095 (CWE28_09090) - 1844420..1844722 (-) 303 WP_023114713.1 hypothetical protein -
  CWE28_RS09100 (CWE28_09095) - 1844722..1845774 (-) 1053 WP_004352271.1 pyocin knob domain-containing protein -
  CWE28_RS09105 (CWE28_09100) - 1845870..1846100 (-) 231 WP_004352270.1 hypothetical protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24225.01 Da        Isoelectric Point: 8.0525

>NTDB_id=261066 CWE28_RS09070 WP_003085214.1 1840579..1841223(+) (crp) [Pseudomonas aeruginosa strain HS9]
MVAITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFEK
EGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKTTRKVGDLAFLDVTGRVARTLLDLCQQPD
AMTHPDGMQIKITRQEIGRIVGCSREMVGRVLKSLEEQGLVHVKGKTMVVFGTR

Nucleotide


Download         Length: 645 bp        

>NTDB_id=261066 CWE28_RS09070 WP_003085214.1 1840579..1841223(+) (crp) [Pseudomonas aeruginosa strain HS9]
ATGGTAGCTATTACCCACACACCCAAACTCAAACACCTAGACAAGCTGCTCGCACACTGTCACCGCCGCCGCTACACCGC
AAAGAGCACCATCATCTATGCCGGCGATCGCTGCGAAACGCTGTTCTTCATCATCAAGGGTTCGGTCACCATCCTCATCG
AGGACGACGACGGCCGCGAAATGATCATCGGCTACCTCAACAGCGGTGATTTCTTCGGCGAGCTGGGATTGTTCGAAAAG
GAAGGCAGCGAACAGGAACGCAGCGCCTGGGTTCGCGCCAAGGTGGAATGCGAAGTCGCCGAGATCAGCTATGCGAAGTT
CCGCGAACTGTCGCAGCAGGACTCGGAGATCCTCTACACCCTCGGCAGCCAGATGGCCGACCGCCTGCGCAAGACCACCC
GCAAGGTGGGCGACCTGGCCTTCCTCGACGTCACCGGACGCGTCGCCCGCACCTTGCTGGACCTGTGCCAGCAACCGGAC
GCCATGACCCACCCGGACGGCATGCAGATCAAGATCACCCGCCAGGAGATCGGCCGGATCGTCGGCTGCTCGCGGGAAAT
GGTCGGACGCGTGCTGAAGAGCCTGGAGGAGCAGGGCCTGGTGCATGTGAAAGGAAAGACCATGGTGGTCTTCGGCACCC
GCTGA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(22-114)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(146-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2ZLY6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

67.327

94.393

0.636
  crp Haemophilus influenzae Rd KW20

60.396

94.393

0.57
  crp Acinetobacter baumannii D1279779

54.545

92.523

0.505