Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   HAC_RS07190 Genome accession   NC_008229
Coordinates   1471827..1474190 (-) Length   787 a.a.
NCBI ID   WP_011578476.1    Uniprot ID   Q17VD3
Organism   Helicobacter acinonychis str. Sheeba     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1466827..1479190
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HAC_RS07170 (Hac_1687) lpxE 1467348..1467920 (+) 573 WP_011578472.1 lipid A 1-phosphatase LpxE -
  HAC_RS07175 (Hac_1688) nspC 1467927..1469144 (-) 1218 WP_011578473.1 carboxynorspermidine decarboxylase -
  HAC_RS07180 (Hac_1689) cheV1 1469141..1470106 (-) 966 WP_011578474.1 chemotaxis protein CheV1 -
  HAC_RS07185 (Hac_1690) - 1470206..1471639 (-) 1434 WP_011578475.1 COG3014 family protein -
  HAC_RS07190 (Hac_1691) comB4 1471827..1474190 (-) 2364 WP_011578476.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  HAC_RS07195 (Hac_1692) comB3 1474192..1474455 (-) 264 WP_011578477.1 hypothetical protein Machinery gene
  HAC_RS07200 (Hac_1693) comB2 1474455..1474736 (-) 282 WP_011578478.1 TrbC/VirB2 family protein Machinery gene
  HAC_RS07205 (Hac_1694) - 1474869..1475696 (-) 828 WP_011578479.1 DUF5718 family protein -
  HAC_RS07210 (Hac_1695) - 1475787..1476839 (-) 1053 WP_011578480.1 MnmA/TRMU family protein -
  HAC_RS07215 (Hac_1696) dnaG 1476836..1478515 (-) 1680 WP_011578481.1 DNA primase -
  HAC_RS07220 (Hac_1697) groES 1478795..1479151 (+) 357 WP_011578482.1 co-chaperone GroES -

Sequence

Protein


Download         Length: 787 a.a.        Molecular weight: 90279.06 Da        Isoelectric Point: 9.1158

>NTDB_id=26075 HAC_RS07190 WP_011578476.1 1471827..1474190(-) (comB4) [Helicobacter acinonychis str. Sheeba]
MLEKLVSAIKQKISNYFLGVLPKSYSMSEENNILGLYDEHFLLTKNENLVGVLRLEGVSYTHLSVEQLQDLFTDRQMALD
SLEKVVARIVVKRRKIDYQQNIQANSQHLQAILNQFENKEVYENQYFLVLESTHSLQGVLEHKKKSLMHANRENFKDILS
YKVHFLQETLRSLEIQLKNYAPKLLNSKEVLNFYAEYINGFELPLKPLVGGYLSDSYIASSVTFEKDYFIQESFNQKIYN
RLIGIKAYESERITSIAIGALLYQETPLDIIFSIEPMSVHKTLSFLKERAKFSMSGLVKNELLEYQELVKTKRLSMQKFA
LNILIKAPSLGRLDAQTSLILGLLFKENLVGVIETFGLKGGYFSFFPECIHLNHRLRFLTSKALACLMVFERQNLGFKAN
SWGNSPLSVFKNLDYSPFLFNFHNQEVGHKNAKEIPRVNGHTLIIGATGSGKSTLMSFLMMSALKYQNMRLLAFDRMQGL
YSFTEFFKGYYHDGKSFSINPFCLEPNLQNLEFLQSFFLSMFDLTPSRNKEALEDMNAISSAIKSLYETLYPKAFSLLDF
KETLKRTSSNQLGLSLEPYLNNPLFNALNDAFNSNAFLNVINLDTITQNPKDLGLLAYYLFYKILEESRKNDSGFLVFLD
EFKSYVENDLLNTKINALITQARKANGVVVLALQDIYQLSGVKNAHSFLSNMGTLILYPQKNARELKNHFNVPLSETEIS
FLENTPLYARQVLVKNLGNGSSNMIDVSLESLGRYLKIFNSDSSHVNKVKALQKDYPKEWREKLLKS

Nucleotide


Download         Length: 2364 bp        

>NTDB_id=26075 HAC_RS07190 WP_011578476.1 1471827..1474190(-) (comB4) [Helicobacter acinonychis str. Sheeba]
ATGCTAGAAAAGCTTGTAAGCGCTATCAAACAAAAAATTTCAAACTATTTTTTAGGGGTTTTGCCTAAAAGCTATTCTAT
GAGCGAAGAAAACAATATCCTAGGCTTGTATGATGAGCATTTTTTACTCACTAAAAATGAAAATCTCGTTGGCGTCCTCC
GGTTAGAGGGGGTTAGTTATACCCATTTGAGCGTGGAGCAATTGCAAGATCTTTTCACGGATCGCCAAATGGCGTTGGAT
TCTTTAGAAAAAGTCGTGGCGCGAATCGTGGTTAAAAGGCGTAAAATTGATTATCAACAAAATATTCAAGCCAATTCCCA
ACACTTGCAAGCGATTTTAAACCAGTTTGAAAACAAAGAAGTGTATGAGAATCAGTATTTTTTAGTTTTAGAAAGCACGC
ATTCCTTGCAAGGCGTTTTAGAGCATAAGAAAAAATCCTTAATGCACGCTAATAGAGAAAATTTTAAGGATATTCTCTCT
TATAAAGTGCATTTTTTACAAGAAACTTTAAGAAGTTTAGAAATCCAACTCAAAAATTATGCCCCCAAACTCTTAAACTC
TAAAGAAGTTTTGAATTTTTACGCAGAATACATCAATGGGTTTGAACTGCCTTTAAAGCCTTTAGTAGGAGGGTATTTGA
GCGATAGCTATATCGCTAGTTCTGTTACTTTTGAAAAAGATTATTTCATTCAAGAAAGCTTCAATCAAAAAATTTACAAC
CGCTTGATTGGCATTAAAGCCTATGAGAGCGAACGCATCACCTCCATAGCGATTGGGGCACTCTTATACCAAGAGACACC
ATTAGATATTATCTTTTCCATAGAGCCTATGAGTGTGCATAAAACGCTGAGTTTTTTAAAAGAAAGGGCTAAGTTTAGCA
TGTCTGGTCTCGTTAAAAACGAATTATTAGAATACCAAGAACTGGTCAAAACCAAACGATTATCCATGCAAAAATTCGCT
TTAAACATTCTTATTAAAGCCCCTAGTTTAGGGAGATTAGACGCTCAAACAAGCTTAATTTTAGGGCTTTTATTTAAAGA
AAACTTAGTGGGTGTTATAGAAACTTTTGGCTTGAAGGGAGGGTATTTTTCTTTTTTCCCTGAATGCATCCATTTAAACC
ACCGCTTGCGTTTTTTAACCTCTAAAGCCTTAGCGTGTTTAATGGTCTTTGAAAGGCAAAATTTAGGTTTTAAGGCTAAT
TCATGGGGGAATAGCCCTTTGAGTGTGTTTAAAAATTTGGATTATTCCCCTTTTTTATTCAATTTCCACAACCAAGAAGT
GGGCCACAAAAACGCTAAAGAAATCCCTAGAGTGAATGGGCATACGCTAATCATAGGGGCTACTGGGAGCGGTAAAAGCA
CGCTGATGAGCTTTTTGATGATGAGCGCTTTGAAATACCAAAACATGCGCCTTTTAGCCTTTGATAGGATGCAAGGGCTG
TATTCTTTCACAGAGTTTTTTAAAGGGTATTACCATGACGGCAAATCTTTTAGCATCAACCCCTTTTGTTTAGAGCCTAA
TTTGCAAAATTTAGAGTTTTTGCAATCTTTCTTTTTGAGCATGTTTGATCTTACGCCTTCAAGGAATAAAGAAGCCCTAG
AAGACATGAATGCGATTTCTAGTGCGATTAAGAGCCTTTATGAGACTTTATACCCTAAAGCCTTTAGTTTGCTAGATTTT
AAAGAAACGCTTAAAAGAACCTCATCTAACCAATTGGGTTTGAGTTTAGAGCCGTATTTGAATAACCCCCTTTTTAACGC
CCTGAATGACGCATTCAATTCCAACGCTTTTTTAAATGTGATCAATCTAGACACAATCACTCAAAACCCTAAAGATTTAG
GGCTTTTAGCCTATTATTTGTTTTATAAAATCTTAGAAGAATCCAGGAAAAACGATAGCGGTTTTTTGGTTTTTTTAGAC
GAGTTTAAATCCTATGTGGAAAACGATTTATTGAACACTAAAATTAACGCTTTAATCACGCAAGCCAGAAAAGCTAATGG
CGTGGTGGTGTTAGCCTTGCAAGATATTTACCAACTGAGTGGGGTCAAAAACGCCCATAGTTTTTTAAGCAACATGGGGA
CTCTTATTTTGTATCCGCAAAAAAACGCTAGAGAATTGAAAAATCATTTCAATGTGCCTTTGAGCGAAACTGAAATTTCT
TTTTTAGAAAACACCCCTTTGTATGCCAGACAGGTTTTAGTCAAAAATTTAGGTAATGGGAGTTCTAACATGATTGATGT
GAGTTTGGAGAGCTTGGGGCGTTATTTGAAAATCTTTAATTCAGACTCTAGTCATGTCAATAAAGTGAAAGCACTACAAA
AAGACTATCCTAAAGAATGGCGTGAAAAACTTTTGAAGAGTTAG

Domains

Predicted by InterproScan.

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(176-375)

FtsK/SpoIIIE family (FtsK_SpoIIIE)

(421-466)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q17VD3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

95.553

100

0.956

Multiple sequence alignment