Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CSC38_RS18570 Genome accession   NZ_CP030337
Coordinates   3399772..3400404 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain AR_451     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3394772..3405404
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CSC38_RS18540 (CSC38_3398) yheS 3394941..3396854 (+) 1914 WP_000634830.1 ABC transporter ATP-binding protein -
  CSC38_RS18545 (CSC38_3399) yheT 3396854..3397876 (+) 1023 WP_000057364.1 hydrolase -
  CSC38_RS18550 (CSC38_3400) yheU 3397870..3398088 (+) 219 WP_000907085.1 YheU family protein -
  CSC38_RS18555 (CSC38_3401) prkB 3398142..3399011 (+) 870 WP_001274684.1 phosphoribulokinase -
  CSC38_RS18560 (CSC38_3402) yhfA 3399066..3399470 (-) 405 WP_001148908.1 OsmC family protein -
  CSC38_RS18570 (CSC38_3403) crp 3399772..3400404 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  CSC38_RS18575 (CSC38_3404) yhfK 3400455..3402545 (+) 2091 WP_001296470.1 YccS/YhfK family putative transporter -
  CSC38_RS18580 (CSC38_3405) argD 3402612..3403832 (-) 1221 WP_000963794.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  CSC38_RS18585 (CSC38_3406) pabA 3403918..3404481 (-) 564 WP_000601853.1 aminodeoxychorismate synthase component 2 -
  CSC38_RS18590 (CSC38_3407) fic 3404513..3405115 (-) 603 WP_001280613.1 putative adenosine monophosphate-protein transferase Fic -
  CSC38_RS18595 yhfG 3405105..3405272 (-) 168 WP_000736858.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=260075 CSC38_RS18570 WP_000242755.1 3399772..3400404(+) (crp) [Escherichia coli strain AR_451]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=260075 CSC38_RS18570 WP_000242755.1 3399772..3400404(+) (crp) [Escherichia coli strain AR_451]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467