Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   DQW89_RS02145 Genome accession   NZ_CP030281
Coordinates   438087..438719 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain E308     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 433087..443719
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQW89_RS02120 (DQW89_02120) yhfG 433219..433386 (+) 168 WP_000736862.1 YhfG family protein -
  DQW89_RS02125 (DQW89_02125) fic 433376..433978 (+) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  DQW89_RS02130 (DQW89_02130) pabA 434010..434573 (+) 564 WP_001753126.1 aminodeoxychorismate synthase component 2 -
  DQW89_RS02135 (DQW89_02135) argD 434659..435879 (+) 1221 WP_118393754.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  DQW89_RS02140 (DQW89_02140) yhfK 435946..438036 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  DQW89_RS02145 (DQW89_02145) crp 438087..438719 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  DQW89_RS02155 (DQW89_02155) yhfA 439021..439425 (+) 405 WP_001148908.1 OsmC family protein -
  DQW89_RS02160 (DQW89_02160) prkB 439480..440349 (-) 870 WP_001274680.1 phosphoribulokinase -
  DQW89_RS02165 (DQW89_02165) yheU 440403..440621 (-) 219 WP_000907085.1 YheU family protein -
  DQW89_RS02170 (DQW89_02170) yheT 440615..441637 (-) 1023 WP_001753125.1 hydrolase -
  DQW89_RS02175 (DQW89_02175) yheS 441637..443550 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=259593 DQW89_RS02145 WP_000242755.1 438087..438719(-) (crp) [Escherichia coli strain E308]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=259593 DQW89_RS02145 WP_000242755.1 438087..438719(-) (crp) [Escherichia coli strain E308]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467