Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   DQ228_RS08315 Genome accession   NZ_CP030250
Coordinates   1614540..1615343 (+) Length   267 a.a.
NCBI ID   WP_228024405.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain CS20     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1609540..1620343
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQ228_RS08285 - 1609739..1610131 (-) 393 WP_003094909.1 hypothetical protein -
  DQ228_RS08290 cipB 1610143..1610382 (-) 240 WP_011681565.1 Blp family class II bacteriocin Regulator
  DQ228_RS10190 - 1610633..1611034 (-) 402 WP_011226490.1 hypothetical protein -
  DQ228_RS08295 - 1612039..1612269 (-) 231 WP_011226494.1 bacteriocin class II family protein -
  DQ228_RS08300 - 1612626..1612826 (-) 201 WP_011681569.1 hypothetical protein -
  DQ228_RS08305 - 1612819..1613022 (-) 204 WP_232979828.1 Blp family class II bacteriocin -
  DQ228_RS08310 - 1613272..1614009 (+) 738 WP_024010062.1 LytR/AlgR family response regulator transcription factor -
  DQ228_RS08315 comD/blpH 1614540..1615343 (+) 804 WP_228024405.1 ATP-binding protein Regulator
  DQ228_RS08320 - 1615361..1615522 (-) 162 WP_011681573.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  DQ228_RS08325 comB 1615537..1616904 (-) 1368 WP_011681574.1 bacteriocin secretion accessory protein Regulator
  DQ228_RS08330 - 1616920..1619074 (-) 2155 Protein_1631 peptide cleavage/export ABC transporter -

Sequence

Protein


Download         Length: 267 a.a.        Molecular weight: 30694.97 Da        Isoelectric Point: 4.8279

>NTDB_id=259557 DQ228_RS08315 WP_228024405.1 1614540..1615343(+) (comD/blpH) [Streptococcus thermophilus strain CS20]
MYLENTTHSSTLELRKLCVVISLVLFFIMIVFLDRNIREMIQGQLDFQKNLQLENLYTYNKHIEGLYNSVRSFRHDYSNL
LVTLRLGIDKDDMDIVKEAYDSVLQESDKRLNTRNFDLARLVNIQDNTLKSLLSAKVLQAEEEGIEAQISIPEPIHLIGM
ETLDFIIVTSIFLDNAIEGAIQTQNPKITISFWEDHRSQLLSISNTISEEKTETKTIFERGVSNKGRERGIGLANVTEIL
DNYINVNLETQSNNFSFTQQLTITKKA

Nucleotide


Download         Length: 804 bp        

>NTDB_id=259557 DQ228_RS08315 WP_228024405.1 1614540..1615343(+) (comD/blpH) [Streptococcus thermophilus strain CS20]
ATGTATCTTGAAAACACTACTCATTCTTCAACTTTGGAGCTTCGAAAACTCTGTGTTGTTATTTCACTTGTCCTCTTCTT
CATTATGATTGTCTTTTTAGACAGAAACATTCGTGAAATGATTCAAGGACAATTGGACTTCCAAAAAAATCTCCAGCTAG
AAAATCTCTACACCTACAATAAACATATTGAAGGTCTCTACAATTCTGTTCGTAGTTTTAGACACGATTATAGTAATCTC
TTAGTCACATTACGATTGGGGATAGATAAAGACGATATGGATATTGTCAAAGAAGCCTATGATAGTGTGCTTCAAGAATC
CGATAAACGATTAAATACAAGAAACTTTGACTTAGCTAGACTCGTTAATATTCAGGATAACACTTTGAAAAGCCTTCTGT
CCGCAAAAGTTCTACAAGCAGAAGAAGAAGGCATTGAAGCTCAGATTAGCATCCCAGAACCCATCCACTTGATTGGGATG
GAGACTCTGGACTTCATTATCGTCACTTCTATTTTTTTAGATAACGCTATTGAAGGTGCCATTCAAACTCAAAACCCTAA
AATTACTATTAGCTTTTGGGAAGATCATCGTTCACAGCTATTATCTATTAGCAATACCATAAGTGAAGAAAAAACAGAAA
CCAAAACCATATTTGAAAGAGGTGTCTCCAACAAGGGACGAGAGCGAGGCATTGGCCTTGCTAATGTCACAGAAATCTTA
GATAACTATATCAATGTAAACTTAGAAACACAGAGTAACAATTTCTCATTCACACAACAATTAACAATAACTAAAAAGGC
CTAA

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(160-263)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

38.189

95.131

0.363

Multiple sequence alignment