Detailed information NTG0025843

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: MGAS9429_RS02200
• Genome accession: NC_008021
• Coordinates: 418597..419598 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes MGAS9429
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 413597..424598

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS9429_RS02175 (MGAS9429_Spy0418)	-	414271..414954 (-)	684	WP_002990714.1	DUF969 domain-containing protein	-
MGAS9429_RS02180 (MGAS9429_Spy0419)	-	415165..416091 (-)	927	WP_002990711.1	glycosyltransferase family 2 protein	-
MGAS9429_RS02185 (MGAS9429_Spy0420)	-	416236..416613 (-)	378	WP_002985686.1	VOC family protein	-
MGAS9429_RS02190 (MGAS9429_Spy0421)	-	416624..417289 (-)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
MGAS9429_RS02195 (MGAS9429_Spy0422)	-	417338..418423 (-)	1086	WP_002990707.1	aminopeptidase P family protein	-
MGAS9429_RS02200 (MGAS9429_Spy0423)	ccpA	418597..419598 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
MGAS9429_RS02205 (MGAS9429_Spy0424)	-	419729..420727 (+)	999	WP_002990703.1	glycosyltransferase family 4 protein	-
MGAS9429_RS02210 (MGAS9429_Spy0425)	-	420729..422063 (+)	1335	WP_002990700.1	glycosyltransferase family 4 protein	-
MGAS9429_RS02215 (MGAS9429_Spy0426)	thrS	422485..424428 (+)	1944	WP_002985672.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=25843 MGAS9429_RS02200 WP_002985680.1 418597..419598(+) (ccpA) [Streptococcus pyogenes MGAS9429]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=25843 MGAS9429_RS02200 WP_002985680.1 418597..419598(+) (ccpA) [Streptococcus pyogenes MGAS9429]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559