Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   DK876_RS07285 Genome accession   NZ_CP030022
Coordinates   1486600..1487283 (-) Length   227 a.a.
NCBI ID   WP_012027525.1    Uniprot ID   A0A0H3MWH7
Organism   Streptococcus suis strain ISU2714     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1481600..1492283
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK876_RS07260 (DK876_07525) - 1481641..1481805 (-) 165 WP_012027521.1 hypothetical protein -
  DK876_RS07265 (DK876_07535) tnpA 1482111..1482575 (-) 465 WP_012775157.1 IS200/IS605-like element ISSsu4 family transposase -
  DK876_RS07270 (DK876_07540) - 1482750..1484759 (-) 2010 WP_012775277.1 ABC transporter permease -
  DK876_RS07275 (DK876_07545) - 1484761..1485519 (-) 759 WP_012027523.1 ABC transporter ATP-binding protein -
  DK876_RS07280 (DK876_07550) - 1485615..1486607 (-) 993 WP_012027524.1 HAMP domain-containing sensor histidine kinase -
  DK876_RS07285 (DK876_07555) braR 1486600..1487283 (-) 684 WP_012027525.1 response regulator transcription factor Regulator
  DK876_RS07290 (DK876_07560) - 1487453..1488634 (+) 1182 WP_012027526.1 DUF2974 domain-containing protein -
  DK876_RS07295 (DK876_07565) - 1488649..1489773 (-) 1125 WP_012027527.1 aminotransferase -
  DK876_RS07300 (DK876_07570) - 1489920..1490681 (-) 762 WP_012027528.1 nuclear transport factor 2 family protein -
  DK876_RS07305 (DK876_07575) - 1490691..1492202 (-) 1512 WP_044475282.1 ABC transporter permease/substrate-binding protein -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 26581.80 Da        Isoelectric Point: 4.5525

>NTDB_id=258288 DK876_RS07285 WP_012027525.1 1486600..1487283(-) (braR) [Streptococcus suis strain ISU2714]
MQKILLIEDDKTISQLVAKNLINWGYQVQEVKDFQMVLEQMEEFQPHLILLDIGLPFFNGYYWCQEIRKTSRVPIMFLSS
HDQPMDIVMAINMGADDYVTKPFEMTVLLAKIQGLLRRTYDFVGEQSLLWFEEISLDLKTMQVSYGQVVEELTRNEFQIL
RVLFEHGKEVVSREELMRELWNSDIFVDDNTLSVNIARLRKKLAELDLPDVIATKKGVGYGLVWTHE

Nucleotide


Download         Length: 684 bp        

>NTDB_id=258288 DK876_RS07285 WP_012027525.1 1486600..1487283(-) (braR) [Streptococcus suis strain ISU2714]
ATGCAGAAAATTCTTCTTATCGAGGATGATAAAACGATTAGCCAACTAGTTGCTAAAAACTTGATAAACTGGGGTTACCA
GGTGCAAGAGGTCAAGGATTTTCAGATGGTTTTGGAACAGATGGAAGAGTTTCAGCCCCATTTGATTTTACTGGATATTG
GTCTGCCGTTTTTCAATGGCTATTACTGGTGTCAGGAAATTCGCAAGACATCCCGTGTGCCCATTATGTTTCTGTCTTCC
CATGACCAGCCAATGGATATTGTTATGGCGATCAATATGGGGGCGGATGACTATGTGACCAAGCCCTTTGAAATGACGGT
TCTCCTGGCCAAAATACAGGGGCTTCTTAGAAGAACCTATGACTTTGTCGGAGAACAAAGTTTACTCTGGTTTGAGGAGA
TTTCCCTAGACCTAAAGACCATGCAGGTGTCCTATGGACAGGTTGTGGAAGAGCTGACGCGAAATGAATTTCAGATTTTA
CGCGTTTTATTTGAACATGGCAAGGAAGTGGTCAGCCGTGAGGAGCTGATGAGAGAACTCTGGAACAGTGATATTTTTGT
GGATGACAATACCCTGTCGGTTAACATCGCTCGCCTGCGTAAGAAATTGGCAGAACTGGATCTGCCAGATGTGATTGCGA
CCAAGAAAGGAGTAGGCTACGGCCTGGTGTGGACACATGAATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MWH7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

47.706

96.035

0.458
  vicR Streptococcus mutans UA159

39.13

100

0.396
  micA Streptococcus pneumoniae Cp1015

37.991

100

0.383