Detailed information NTG0025828

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: MGAS9429_RS00670
• Genome accession: NC_008021
• Coordinates: 104741..105175 (+)
• Length: 144 a.a.
• NCBI ID: WP_002987783.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes MGAS9429
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 99741..110175

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS9429_RS00640 (MGAS9429_Spy0086)	-	101410..101775 (+)	366	WP_002986560.1	DUF1033 family protein	-
MGAS9429_RS00645 (MGAS9429_Spy0087)	comYA	101868..102806 (+)	939	WP_002987773.1	competence type IV pilus ATPase ComGA	Machinery gene
MGAS9429_RS00650 (MGAS9429_Spy0088)	comYB	102742..103776 (+)	1035	WP_223845212.1	competence type IV pilus assembly protein ComGB	Machinery gene
MGAS9429_RS00655 (MGAS9429_Spy0089)	comYC	103778..104104 (+)	327	WP_002986552.1	competence type IV pilus major pilin ComGC	Machinery gene
MGAS9429_RS00660 (MGAS9429_Spy0090)	comGD	104079..104507 (+)	429	WP_002986548.1	competence type IV pilus minor pilin ComGD	-
MGAS9429_RS00665 (MGAS9429_Spy0091)	comGE	104464..104748 (+)	285	WP_002987779.1	competence type IV pilus minor pilin ComGE	-
MGAS9429_RS00670 (MGAS9429_Spy0092)	comYF	104741..105175 (+)	435	WP_002987783.1	competence type IV pilus minor pilin ComGF	Machinery gene
MGAS9429_RS00675 (MGAS9429_Spy0093)	comGG	105159..105485 (+)	327	WP_002987787.1	competence type IV pilus minor pilin ComGG	-
MGAS9429_RS00680 (MGAS9429_Spy0094)	comYH	105583..106536 (+)	954	WP_002987790.1	class I SAM-dependent methyltransferase	Machinery gene
MGAS9429_RS00685 (MGAS9429_Spy0095)	-	106595..107791 (+)	1197	WP_002987791.1	acetate kinase	-
MGAS9429_RS00690 (MGAS9429_Spy0096)	-	107978..108286 (+)	309	WP_011284425.1	hypothetical protein	-
MGAS9429_RS00695 (MGAS9429_Spy0097)	proC	108369..109139 (-)	771	WP_002986527.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16585.23 Da
• Isoelectric Point: 10.2064

>NTDB_id=25828 MGAS9429_RS00670 WP_002987783.1 104741..105175(+) (comYF) [Streptococcus pyogenes MGAS9429]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYLARHDQDNWLLFSHQLREELSGARFCKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD

Nucleotide

• Length: 435 bp

>NTDB_id=25828 MGAS9429_RS00670 WP_002987783.1 104741..105175(+) (comYF) [Streptococcus pyogenes MGAS9429]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCCTCCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCAAACCCTCCTTAAACGTAGCCATTACCTAGCCCGTCATGATCAAGACAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGATTTTGCAAAGTAGCTGATAATAAACTATACGTTGAAAAA
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTTCGAAAATCAGCTAGTAATGGAAAAGGATATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGAGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (41-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	51.079	96.528	0.493
comYF	Streptococcus mutans UA159	50.36	96.528	0.486
comGF	Lactococcus lactis subsp. cremoris KW2	46.715	95.139	0.444
comGF/cglF	Streptococcus mitis NCTC 12261	44.776	93.056	0.417
comGF/cglF	Streptococcus pneumoniae Rx1	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae D39	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae R6	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae TIGR4	43.609	92.361	0.403
comGF/cglF	Streptococcus mitis SK321	42.857	92.361	0.396