Detailed information NTG0258269

Bioinformatically predicted

Overview

• Name: uvrB
• Type: Machinery gene
• Locus tag: DK876_RS04790
• Genome accession: NZ_CP030022
• Coordinates: 981187..983172 (-)
• Length: 661 a.a.
• NCBI ID: WP_012028187.1
• Uniprot ID: A0A0H3N3Z6
• Organism: Streptococcus suis strain ISU2714
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 976187..988172

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DK876_RS04780 (DK876_04965)	-	979208..979306 (-)	99	Protein_893	UvrB/UvrC motif-containing protein	-
DK876_RS04785 (DK876_04970)	-	979349..981172 (-)	1824	WP_014636397.1	DUF2971 domain-containing protein	-
DK876_RS04790 (DK876_04975)	uvrB	981187..983172 (-)	1986	WP_012028187.1	excinuclease ABC subunit UvrB	Machinery gene
DK876_RS04795 (DK876_04980)	-	983370..985568 (+)	2199	WP_012775143.1	ABC transporter substrate-binding protein/permease	-
DK876_RS04800 (DK876_04985)	-	985568..986308 (+)	741	WP_002940438.1	amino acid ABC transporter ATP-binding protein	-
DK876_RS04805 (DK876_04990)	-	986562..987053 (-)	492	WP_011922516.1	GNAT family N-acetyltransferase	-

Sequence

Protein

• Length: 661 a.a.
• Molecular weight: 75592.64 Da
• Isoelectric Point: 4.5993

>NTDB_id=258269 DK876_RS04790 WP_012028187.1 981187..983172(-) (uvrB) [Streptococcus suis strain ISU2714]
MINRNTENQFKLVSKYAPSGDQPQAIETLVDNIEGGEKAQILMGATGTGKTYTMSQVIARVNKPTLVIAHNKTLAGQLYS
EFKEFFPENAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYS
DSVVSLRPGQEISRDQLLNALVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFRVEFFGDEIDRIREIESLTGKVL
GDVDHLAIFPATHFVTNDDHMETAIAKIQAELEEQLKVFEAEGKLLEAQRLKQRTDYDIEMLREMGYTNGVENYSRHMDG
RSEGEPPYTLLDFFPEDYLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGDYEMEQTETVVEQIIRPTGLLDPEVEVRPTMGQMDDLLGEINARVEKGERTFITTLTKKMAEDLTDYLKEMGVKVKYM
HSDIKTLERTEIIRDLRLGVFDVLIGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADK
VTESMRKAMEETARRRQIQMAYNEEHGIIPQTIKKEIRDLISVTKAVTQDKEEVVDFNALNKDERKAMIKKLEGQMQEAA
EVLDFELAAQIRDMVIELKNM

Nucleotide

• Length: 1986 bp

>NTDB_id=258269 DK876_RS04790 WP_012028187.1 981187..983172(-) (uvrB) [Streptococcus suis strain ISU2714]
ATGATCAATCGAAATACTGAAAACCAATTTAAACTTGTGTCAAAATATGCACCGTCTGGTGACCAGCCCCAAGCCATTGA
AACCTTGGTTGATAACATCGAGGGGGGCGAAAAAGCCCAGATTCTCATGGGGGCGACTGGTACTGGTAAGACCTATACCA
TGAGCCAGGTTATCGCCCGTGTCAATAAGCCAACCTTGGTCATCGCCCACAACAAGACCTTGGCTGGTCAGCTTTATAGT
GAGTTCAAGGAATTCTTTCCAGAAAATGCGGTCGAATACTTCGTGTCTTACTATGATTACTACCAGCCAGAAGCTTATGT
ACCGTCTAGCGATACCTATATCGAAAAGGATAGTTCGGTCAATGATGAGATTGACAAACTCCGTCACTCTGCGACCTCAG
CTCTGCTAGAACGCAATGATGTCATTGTGGTAGCTTCTGTTTCTTGTATCTACGGTTTGGGTTCACCCAAGGAATATTCA
GATAGCGTGGTCAGCCTGCGACCAGGTCAGGAGATTTCCCGTGATCAGTTGCTCAATGCCTTGGTGGATATCCAGTTTGA
GCGGAACGACATCGACTTCCAACGGGGACGGTTCCGTGTGCGTGGCGATGTGGTGGAGATTTTCCCAGCTTCCCGTGACG
AACATGCCTTTCGTGTGGAGTTTTTCGGGGATGAAATCGACCGCATTCGTGAGATTGAAAGCCTGACAGGCAAGGTTTTG
GGCGATGTGGACCACTTGGCCATTTTCCCTGCCACCCACTTCGTGACCAACGATGACCACATGGAAACGGCCATTGCCAA
GATTCAGGCGGAACTAGAAGAGCAACTCAAGGTCTTTGAGGCAGAAGGAAAACTCTTAGAAGCTCAGCGATTGAAACAAC
GAACCGACTACGATATCGAGATGCTTCGGGAGATGGGCTATACCAACGGAGTTGAGAACTATTCACGACACATGGACGGG
CGAAGTGAGGGGGAGCCTCCTTATACCCTGCTGGACTTTTTCCCTGAGGACTATCTGATTATGATTGACGAGAGCCACAT
GACCATGGGGCAGATTAAGGGGATGTACAATGGTGACCGCTCACGCAAGGAGATGCTGGTTAACTATGGTTTCCGTCTAC
CGAGTGCATTGGATAATCGTCCGCTGCGCAGGGAAGAATTTGAGAGTCATGTCCACCAGATTGTCTATGTATCTGCGACG
CCGGGTGACTATGAAATGGAGCAGACAGAGACCGTTGTCGAGCAGATTATCCGGCCGACCGGGCTTTTGGATCCAGAAGT
GGAAGTCCGTCCAACTATGGGCCAAATGGACGACCTCCTAGGTGAAATCAATGCCCGTGTTGAAAAAGGCGAGCGAACCT
TTATCACTACCCTGACCAAGAAAATGGCAGAGGACTTGACCGACTACCTGAAAGAAATGGGCGTCAAGGTCAAGTATATG
CACTCGGACATCAAGACCTTGGAGCGTACGGAGATTATCCGTGATCTTCGCTTGGGTGTCTTTGATGTTTTGATAGGGAT
TAACCTGCTTCGTGAAGGGATTGACGTGCCAGAAGTTAGTCTAGTCGCTATCTTAGACGCAGACAAGGAGGGCTTCCTCC
GTAATGAACGGGGGCTCATCCAGACAATCGGTCGAGCGGCTCGTAACTCTGAAGGTCATGTGATTATGTATGCGGACAAG
GTCACCGAGTCCATGCGGAAGGCCATGGAAGAAACAGCCCGCCGCCGTCAAATCCAGATGGCTTATAATGAAGAGCATGG
CATTATTCCACAGACCATTAAGAAAGAGATCCGTGACCTGATTAGCGTGACCAAGGCTGTCACTCAGGACAAGGAAGAGG
TTGTGGACTTCAATGCTCTTAATAAAGATGAACGCAAGGCCATGATCAAGAAACTGGAAGGTCAGATGCAGGAAGCCGCA
GAAGTGCTTGACTTTGAACTGGCAGCCCAGATTCGCGATATGGTCATTGAGTTGAAGAATATGTAG

Domains

Predicted by InterProScan.

• Ultra-violet resistance protein B (UvrB) (556-598)

• Type III restriction enzyme, res subunit (ResIII) (21-143)

• UvrB/uvrC motif (UVR) (626-660)

• UvrB interaction domain (UvrB_inter) (164-254)

• Helicase conserved C-terminal domain (Helicase_C) (445-549)

3D structure

• AlphaFold DB: A0A0H3N3Z6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrB	Streptococcus pneumoniae R6	91.225	100	0.912
uvrB	Streptococcus pneumoniae D39	91.225	100	0.912
uvrB	Streptococcus pneumoniae TIGR4	91.074	100	0.911