Detailed information NTG0258166

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: DK875_RS05575
• Genome accession: NZ_CP030020
• Coordinates: 1149555..1150226 (-)
• Length: 223 a.a.
• NCBI ID: WP_009909965.1
• Uniprot ID: -
• Organism: Streptococcus suis strain ISU2514
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1144555..1155226

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DK875_RS05555 (DK875_05810)	coaA	1145141..1146061 (+)	921	WP_002935283.1	type I pantothenate kinase	-
DK875_RS05560 (DK875_05815)	rpsT	1146120..1146368 (+)	249	WP_012027069.1	30S ribosomal protein S20	-
DK875_RS05565 (DK875_05820)	-	1146630..1147859 (-)	1230	WP_002935288.1	transglutaminase domain-containing protein	-
DK875_RS05570 (DK875_05830)	ciaH	1148183..1149562 (-)	1380	WP_002935290.1	cell wall metabolism sensor histidine kinase WalK	Regulator
DK875_RS05575 (DK875_05835)	ciaR	1149555..1150226 (-)	672	WP_009909965.1	response regulator transcription factor	Regulator
DK875_RS05580 (DK875_05840)	-	1150420..1150800 (-)	381	WP_002935294.1	hypothetical protein	-
DK875_RS05585 (DK875_05845)	-	1151185..1152387 (+)	1203	WP_002935295.1	IS110-like element ISSsu7 family transposase	-
DK875_RS05590 (DK875_05850)	phoU	1152589..1153245 (-)	657	WP_002937611.1	phosphate signaling complex protein PhoU	-
DK875_RS05595 (DK875_05855)	pstB	1153274..1154032 (-)	759	WP_002937614.1	phosphate ABC transporter ATP-binding protein PstB	-
DK875_RS05600 (DK875_05860)	pstB	1154044..1154847 (-)	804	WP_002937615.1	phosphate ABC transporter ATP-binding protein PstB	-

Sequence

Protein

• Length: 223 a.a.
• Molecular weight: 25290.00 Da
• Isoelectric Point: 4.2183

>NTDB_id=258166 DK875_RS05575 WP_009909965.1 1149555..1150226(-) (ciaR) [Streptococcus suis strain ISU2514]
MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGVYEAETGVYDLILLDLMLPEKDGFQVLKELREKGVTTPVLITTA
KESLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENTLTFGDVTVDLSTNMTMVNGEEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFGENLQTLRSVGYILKNA

Nucleotide

• Length: 672 bp

>NTDB_id=258166 DK875_RS05575 WP_009909965.1 1149555..1150226(-) (ciaR) [Streptococcus suis strain ISU2514]
ATGATTAAAATATTGTTAGTGGAAGATGATTTAAGTCTATCAAATTCTGTTTTCGATTTCTTAGATGATTTTGCGGATGT
TATGCAGGTTTTTGATGGTGAAGAGGGCGTTTATGAGGCGGAAACAGGCGTTTATGATTTGATTCTTTTGGATTTGATGT
TGCCTGAAAAAGATGGCTTCCAAGTCTTGAAAGAATTACGTGAAAAAGGTGTTACGACACCTGTTCTGATTACAACAGCC
AAGGAAAGTCTAGAGGATAAAGGCCATGGTTTTGAATTGGGGGCTGATGACTATTTGACAAAACCGTTTTATTTAGAAGA
ATTGAAGATGCGAATTCAAGCTCTATTAAAACGAGCGGGTAAGTTTAATGAAAACACACTAACCTTTGGAGATGTGACAG
TTGACCTATCTACAAATATGACGATGGTAAATGGCGAAGAAGTTGAACTGCTAGGAAAAGAATTTGATCTACTAGTTTAT
TTCTTGCAAAATCAAAATGTTATTTTGCCAAAAACACAAATTTTTGACCGTATTTGGGGCTTTGACAGTGATACTACAAT
TTCAGTAGTAGAAGTATATGTTTCTAAAATTAGGAAAAAGTTGAAAGGAACGACCTTTGGGGAAAATCTTCAAACCCTGC
GTAGTGTCGGATACATTCTAAAAAATGCCTAA

Domains

Predicted by InterProScan.

• Response regulator receiver domain (Response_reg) (4-112)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-220)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus mutans UA159	90.135	100	0.901
ciaR	Streptococcus pneumoniae Rx1	88.341	100	0.883
ciaR	Streptococcus pneumoniae D39	88.341	100	0.883
ciaR	Streptococcus pneumoniae R6	88.341	100	0.883
ciaR	Streptococcus pneumoniae TIGR4	88.341	100	0.883
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.496	100	0.39
vicR	Streptococcus mutans UA159	35.47	100	0.372
covR	Streptococcus salivarius strain HSISS4	35.841	100	0.363