Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   CWI64_RS05835 Genome accession   NZ_CP025076
Coordinates   1076758..1077711 (-) Length   317 a.a.
NCBI ID   WP_000345133.1    Uniprot ID   A0A0T8FEM8
Organism   Streptococcus pneumoniae strain BHN97x     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1071758..1082711
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CWI64_RS05810 (CWI64_05810) - 1072519..1073142 (-) 624 WP_000932661.1 hypothetical protein -
  CWI64_RS05815 (CWI64_05815) jag 1073193..1074179 (-) 987 WP_000260018.1 RNA-binding cell elongation regulator Jag/EloR -
  CWI64_RS05820 (CWI64_05820) - 1074198..1075022 (-) 825 WP_000727904.1 membrane protein insertase YidC -
  CWI64_RS05825 (CWI64_05825) rnpA 1074997..1075368 (-) 372 WP_000739246.1 ribonuclease P protein component -
  CWI64_RS12295 - 1075385..1075516 (-) 132 WP_000768904.1 hypothetical protein -
  CWI64_RS05830 (CWI64_05830) - 1075517..1076707 (-) 1191 WP_000167766.1 acetate kinase -
  CWI64_RS05835 (CWI64_05835) comYH 1076758..1077711 (-) 954 WP_000345133.1 class I SAM-dependent methyltransferase Machinery gene
  CWI64_RS05840 (CWI64_05840) - 1077772..1078373 (-) 602 Protein_1078 methyltransferase domain-containing protein -
  CWI64_RS05845 (CWI64_05845) comGG/cglG 1078510..1078923 (-) 414 WP_000265622.1 competence type IV pilus minor pilin ComGG Machinery gene
  CWI64_RS05850 (CWI64_05850) comGF/cglF 1078901..1079362 (-) 462 WP_000250534.1 competence type IV pilus minor pilin ComGF Machinery gene
  CWI64_RS05855 (CWI64_05855) comGE/cglE 1079325..1079627 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  CWI64_RS05860 (CWI64_05860) comGD/cglD 1079590..1079994 (-) 405 WP_000588024.1 competence type IV pilus minor pilin ComGD Machinery gene
  CWI64_RS05865 (CWI64_05865) comGC/cglC 1079987..1080313 (-) 327 WP_000738630.1 comG operon protein ComGC Machinery gene
  CWI64_RS05870 (CWI64_05870) comGB/cglB 1080315..1081331 (-) 1017 WP_078132591.1 competence type IV pilus assembly protein ComGB Machinery gene
  CWI64_RS05875 (CWI64_05875) comGA/cglA/cilD 1081279..1082220 (-) 942 WP_000249573.1 competence type IV pilus ATPase ComGA Machinery gene
  CWI64_RS05880 (CWI64_05880) - 1082296..1082661 (-) 366 WP_000286415.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35721.90 Da        Isoelectric Point: 4.2665

>NTDB_id=258089 CWI64_RS05835 WP_000345133.1 1076758..1077711(-) (comYH) [Streptococcus pneumoniae strain BHN97x]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQTLKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGFKYLKSDGYAIFLAPSDLLTSPQ
SDLLKVWLKEEASLVAMISLPENLFANAKQSKTIFILQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=258089 CWI64_RS05835 WP_000345133.1 1076758..1077711(-) (comYH) [Streptococcus pneumoniae strain BHN97x]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAATAGCATCTATCTGGATGGTGAAACTGAGTTAAACCAGGTCAAAGACAACAATC
AAACCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCGGATGCTATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAGTGGATGATTTGCTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGCCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTCGG
CTATTATCCTGATGATGCCGTTGCGTCGCGTCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCTCATCACTTGCTCA
TGGAACAAGGGTTTAAGTACCTTAAGTCAGATGGATATGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTGAAAGTCTGGTTGAAAGAGGAGGCAAGTCTGGTTGCTATGATTAGTTTACCTGAAAATCTCTTTGCTAA
TGCTAAACAATCTAAGACTATTTTTATCCTACAGAAGAAAAGTGAAATAGCAGTGGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0T8FEM8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.633

98.738

0.539
  comYH Streptococcus mutans UA159

54.313

98.738

0.536

Multiple sequence alignment