Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   CWI64_RS01680 Genome accession   NZ_CP025076
Coordinates   327030..328379 (-) Length   449 a.a.
NCBI ID   WP_061645482.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain BHN97x     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 322030..333379
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CWI64_RS01655 (CWI64_01655) - 323685..324671 (+) 987 WP_000204727.1 L-lactate dehydrogenase -
  CWI64_RS01660 (CWI64_01660) - 324931..325583 (-) 653 Protein_316 ion transporter -
  CWI64_RS01665 (CWI64_01665) - 325630..325884 (-) 255 WP_001809704.1 type II toxin-antitoxin system RelE/ParE family toxin -
  CWI64_RS01670 (CWI64_01670) - 325886..326128 (-) 243 WP_000208080.1 DUF6290 family protein -
  CWI64_RS01675 (CWI64_01675) vicX 326219..327028 (-) 810 WP_001289493.1 MBL fold metallo-hydrolase Regulator
  CWI64_RS01680 (CWI64_01680) micB 327030..328379 (-) 1350 WP_061645482.1 cell wall metabolism sensor histidine kinase VicK Regulator
  CWI64_RS01685 (CWI64_01685) micA 328372..329076 (-) 705 WP_000722076.1 response regulator YycF Regulator
  CWI64_RS01690 (CWI64_01690) mutY 329131..330306 (-) 1176 WP_000886145.1 A/G-specific adenine glycosylase -
  CWI64_RS12250 - 330403..330528 (+) 126 WP_001818232.1 hypothetical protein -
  CWI64_RS01695 (CWI64_01695) - 330634..332304 (-) 1671 WP_000845292.1 formate--tetrahydrofolate ligase -
  CWI64_RS01700 (CWI64_01700) coaB 332534..333223 (+) 690 WP_000699495.1 phosphopantothenate--cysteine ligase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51740.47 Da        Isoelectric Point: 5.0403

>NTDB_id=258060 CWI64_RS01680 WP_061645482.1 327030..328379(-) (micB) [Streptococcus pneumoniae strain BHN97x]
MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIRLKQINQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSE
VIRLTQENLEQESKRLNSILFYMTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALC
ETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATSHLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIW
MEIDTDKMTQVVDNILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSRAQGGTGLG
LSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=258060 CWI64_RS01680 WP_061645482.1 327030..328379(-) (micB) [Streptococcus pneumoniae strain BHN97x]
ATGCTTGATTTACTGAAACAAACCATTTTTACCAGAGATTTTATCTTTATCCTGATTTTGTTAGGTTTCATCCTTGTTGT
GACCCTCTTATTACTGGAAAATAGACGTGATAATATTCGGTTGAAGCAAATCAATCAAAAGGTTAAAGATTTGATTGCAG
GAGATTATTCCAAGGTTCTTGATATGCAAGGTGGGTCTGAAATCACCAATATTACCAATAATTTGAATGACTTGTCGGAG
GTTATTCGTCTCACTCAGGAAAATCTAGAACAAGAGAGTAAGAGGCTAAATAGTATTCTGTTTTATATGACAGATGGGGT
TCTTGCGACTAACCGTCGGGGTCAGATTATCATGATTAACGATACAGCCAAGAAGCAACTGGGGTTGGTTAAGGAAGATG
TTCTGAATAGAAGCATTTTGGAATTGCTCAAGATAGAAGAAAACTATGAATTGCGTGATTTGATTACCCAAAGTCCAGAA
TTGTTGCTAGATTCCCAAGATATCAATGGCGAATATTTGAACCTTCGAGTTCGCTTTGCCTTGATACGTCGAGAGTCTGG
CTTTATTTCAGGTTTGGTGGCTGTTTTGCATGATACGACGGAGCAGGAGAAGGAAGAACGCGAACGAAGACTCTTTGTTT
CCAATGTTAGCCATGAGTTACGGACTCCTCTGACTAGCGTAAAATCCTATCTTGAAGCCTTGGATGAGGGGGCTTTGTGT
GAAACTGTAGCACCAGACTTTATCAAGGTTTCTCTTGATGAGACCAACCGTATGATGCGCATGGTGACGGATCTCCTCCA
TCTTTCACGTATTGATAATGCTACCAGTCACCTAGATGTGGAACTGATTAACTTCACTGCTTTTATTACCTTTATCCTCA
ATCGTTTTGACAAGATGAAAGGACAGGAAAAGGAGAAAAAATATGAGCTGGTGAGAGATTATCCCATCAATTCTATCTGG
ATGGAAATTGATACAGATAAGATGACGCAGGTTGTCGACAATATTTTAAATAATGCTATTAAGTATTCGCCAGATGGGGG
TAAAATCACTGTCAGAATGAAGACAACTGAAGACCAGATGATTTTATCCATTTCTGACCACGGTTTGGGGATTCCTAAGC
AGGATTTACCACGTATCTTTGACCGTTTCTATCGTGTGGATCGTGCTAGAAGTCGTGCACAAGGTGGTACAGGTCTAGGA
CTGTCTATCGCTAAAGAAATTATCAAACAACATAAGGGCTTTATTTGGGCCAAGAGTGAATACGGCAAGGGTTCAACCTT
TACCATTGTACTCCCTTATGATAAGGATGCAGTGAAAGAAGAAGTATGGGAGGATGAAGTAGAAGACTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(98-198)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

99.555

100

0.996
  vicK Streptococcus mutans UA159

69.652

89.532

0.624

Multiple sequence alignment