Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   DK235_RS03575 Genome accession   NZ_CP030017
Coordinates   728179..729963 (+) Length   594 a.a.
NCBI ID   WP_012775432.1    Uniprot ID   A0A0H3MW45
Organism   Streptococcus suis strain ISU1606     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 723179..734963
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK235_RS03550 (DK235_03695) - 723672..723923 (+) 252 WP_012775055.1 phage holin -
  DK235_RS03555 (DK235_03700) ldcB 724274..725029 (+) 756 WP_012775056.1 LD-carboxypeptidase LdcB/DacB -
  DK235_RS03560 (DK235_03705) - 725118..725561 (+) 444 WP_002935466.1 VOC family protein -
  DK235_RS03565 (DK235_03710) - 725589..727199 (-) 1611 WP_011922277.1 permease -
  DK235_RS03570 (DK235_03715) - 727196..727939 (-) 744 WP_011922278.1 ABC transporter ATP-binding protein -
  DK235_RS03575 (DK235_03720) uvrC 728179..729963 (+) 1785 WP_012775432.1 excinuclease ABC subunit UvrC Machinery gene
  DK235_RS03580 (DK235_03725) - 730020..730148 (+) 129 WP_002935474.1 DUF4044 domain-containing protein -
  DK235_RS03585 (DK235_03730) obgE 730352..731665 (+) 1314 WP_011922805.1 GTPase ObgE -
  DK235_RS03590 (DK235_03735) - 732039..732203 (+) 165 WP_012775058.1 hypothetical protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68141.24 Da        Isoelectric Point: 8.9394

>NTDB_id=258060 DK235_RS03575 WP_012775432.1 728179..729963(+) (uvrC) [Streptococcus suis strain ISU1606]
MNDLIKHKLELLPDSPGCYLHKNKYGKIIYVGKAKNLRNRVRSYFRGAHDTKTEALVAEIADFEFIVTDSNIEALLLEIN
LIQENKPRYNIMLKDDKSYPFIKITKERHPRLLITRQIKKDGGQYFGPYPDVGAANQTLKLLERLYPFRKCKLPENKYCL
YYHLGQCLAHGDNMPSLSDYDKMAKEVAQFLTGHDDKIIKEVQDKMKAAAGNLEFEKAAEYRDVLQSISTLRTKQRVMAH
DLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERNVNLFPYYNDAGEDFLTYIGQFYRDQQHLIPSEVLIPQDIDQEAVEAL
VDTKVIKPQRGEKKQLINLATKNARVSLEQKFNLLEKNLEKTYGAVENIGQLLGIPTPVRIEAFDNSNIMGTSPVSAMVV
FENGVPNKKEYRKYKINTVEGPDDYASMREVLQRRYSRVLRDGLTPPDLIIIDGGQGQVNVAKQVIEQELGMSIPIAGLQ
KNDKHQTHELLFGNPLEVVELPRNSQEFFLLHRIQDEVHRFAIEFHRQVRSKNSFSSKLDGIEGLGPKRKQTLMKHFKSI
GNIQSASLQEIAEAGVPYKVAEKVKESLSSKDEI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=258060 DK235_RS03575 WP_012775432.1 728179..729963(+) (uvrC) [Streptococcus suis strain ISU1606]
ATGAACGATTTGATCAAGCATAAATTGGAGTTACTACCAGATAGCCCTGGCTGTTACCTCCATAAAAACAAGTACGGTAA
GATTATCTATGTGGGCAAGGCCAAAAACCTACGCAATCGGGTGCGGTCTTATTTTCGTGGTGCCCATGATACCAAGACAG
AGGCTCTAGTGGCTGAAATTGCCGATTTTGAATTTATCGTGACGGATTCCAACATCGAGGCCCTCTTGCTAGAAATCAAT
CTGATTCAGGAAAACAAGCCACGCTATAACATCATGCTCAAGGATGACAAGTCTTATCCCTTCATCAAGATTACCAAGGA
ACGTCATCCACGGCTGCTCATTACTCGGCAGATTAAGAAGGATGGTGGTCAGTATTTTGGTCCCTATCCAGATGTGGGTG
CGGCCAACCAGACCCTCAAACTATTGGAGCGCCTCTATCCTTTCCGCAAGTGTAAATTGCCTGAGAACAAGTATTGTCTT
TATTATCATTTGGGGCAATGTTTGGCTCATGGAGACAATATGCCCAGCCTGTCTGACTATGACAAGATGGCCAAGGAAGT
GGCCCAGTTCTTGACAGGTCATGATGATAAGATTATCAAGGAAGTGCAGGACAAGATGAAGGCAGCTGCTGGCAATTTGG
AATTTGAAAAGGCTGCGGAATACCGGGATGTCCTCCAATCCATTTCAACCCTGCGGACCAAGCAACGTGTGATGGCTCAT
GACTTGCAGAATCGAGATGTCTTTGGCTACTACGTAGACAAGGGCTGGATGTGTGTGCAGGTTTTCTTTGTTCGGCAGGG
GAAACTGATTGAGCGGAATGTCAATCTTTTTCCATACTATAATGATGCGGGCGAAGACTTTTTGACCTACATCGGTCAGT
TTTACAGGGACCAGCAACATTTGATTCCCTCAGAGGTCTTGATACCGCAGGATATTGACCAAGAAGCCGTAGAAGCTCTG
GTAGATACCAAGGTCATCAAGCCCCAGCGTGGCGAGAAGAAGCAACTCATCAATCTGGCAACCAAGAATGCGCGTGTCAG
TCTGGAGCAGAAGTTTAATCTTTTGGAGAAAAATCTGGAGAAGACCTACGGTGCGGTGGAGAATATCGGTCAGCTTTTGG
GGATTCCGACGCCTGTGCGGATTGAGGCTTTCGATAACTCCAATATTATGGGGACTAGTCCTGTGTCGGCTATGGTTGTC
TTTGAAAATGGGGTGCCTAATAAAAAAGAATACCGCAAGTACAAGATTAATACGGTTGAGGGACCGGATGACTATGCTTC
CATGCGGGAAGTTTTGCAGCGGCGGTACAGTCGGGTGCTGCGGGACGGTTTGACACCGCCTGATTTGATTATCATTGACG
GTGGTCAGGGGCAGGTCAATGTCGCCAAGCAGGTCATCGAGCAGGAGTTGGGTATGTCCATTCCCATTGCAGGTTTGCAG
AAGAATGACAAGCACCAGACACACGAATTGCTCTTTGGTAATCCGCTGGAAGTAGTTGAGTTGCCTCGCAATTCACAGGA
ATTTTTCCTCCTGCATCGGATTCAAGATGAGGTTCACCGCTTTGCTATTGAGTTTCATCGTCAGGTTCGGTCAAAAAATT
CCTTCTCATCCAAATTGGACGGCATAGAAGGCTTGGGACCAAAACGCAAGCAGACTTTGATGAAGCATTTCAAGTCTATT
GGCAATATCCAGTCGGCCAGTCTACAAGAAATCGCAGAAGCAGGAGTGCCGTATAAAGTAGCGGAAAAGGTCAAGGAAAG
CCTTTCTTCAAAGGATGAGATTTGA

Domains

Predicted by InterProScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)

UvrB/uvrC motif (UVR)

(196-229)

GIY-YIG catalytic domain (GIY-YIG)

(17-90)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MW45

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

76.728

99.832

0.766
  uvrC Streptococcus pneumoniae R6

76.391

99.832

0.763
  uvrC Streptococcus pneumoniae D39

76.391

99.832

0.763

Multiple sequence alignment