Detailed information NTG0257652

Bioinformatically predicted

Overview

• Name: scnR
• Type: Regulator
• Locus tag: CWR56_RS03185
• Genome accession: NZ_CP025045
• Coordinates: 668381..669088 (+)
• Length: 235 a.a.
• NCBI ID: WP_009888460.1
• Uniprot ID: A0A9Q8EBL8
• Organism: Clostridioides difficile strain W0023a
• Function: regulate comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 663381..674088

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CWR56_RS03155 (CWR56_03155)	cdd1	664176..664421 (+)	246	WP_004454326.1	protein Cdd1	-
CWR56_RS03160 (CWR56_03160)	-	664639..664908 (-)	270	WP_003426848.1	DUF3795 domain-containing protein	-
CWR56_RS03170 (CWR56_03170)	-	665786..666523 (-)	738	WP_003439186.1	ABC transporter permease	-
CWR56_RS03175 (CWR56_03175)	-	666535..667296 (-)	762	WP_003439185.1	ABC transporter permease	-
CWR56_RS03180 (CWR56_03180)	-	667296..668219 (-)	924	WP_003439184.1	ABC transporter ATP-binding protein	-
CWR56_RS03185 (CWR56_03185)	scnR	668381..669088 (+)	708	WP_009888460.1	response regulator transcription factor	Regulator
CWR56_RS03190 (CWR56_03190)	-	669133..670539 (+)	1407	WP_021378163.1	sensor histidine kinase	-
CWR56_RS03195 (CWR56_03195)	-	672196..672585 (+)	390	WP_003426867.1	BlaI/MecI/CopY family transcriptional regulator	-
CWR56_RS03200 (CWR56_03200)	-	673183..673653 (+)	471	WP_003439176.1	VOC family protein	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 26716.17 Da
• Isoelectric Point: 6.1467

>NTDB_id=257652 CWR56_RS03185 WP_009888460.1 668381..669088(+) (scnR) [Clostridioides difficile strain W0023a]
MESIKDKKILVVDDHKELLKMIDEILRKEGFSRVFLASSYEEAVRVFRNVKPDCAILDVVLPDGDGFSIMRKIRETSKIP
VIFLSARGEDEDRLIGLGLGADDYIVKPFLPKELTLRLVGILNRVYVPIEEEELPVFKLGDSVVVNLNSACVEKDGQEIS
LTAKEHSLLLKLYENKGRIVTNDSLCQAIWGDDMYGYENTLMVHVRRVREKIEKTPSTPKHLITVRGLGYKLMIN

Nucleotide

• Length: 708 bp

>NTDB_id=257652 CWR56_RS03185 WP_009888460.1 668381..669088(+) (scnR) [Clostridioides difficile strain W0023a]
ATGGAGTCAATAAAAGATAAAAAAATACTTGTGGTTGATGACCACAAGGAATTATTAAAAATGATAGATGAAATCCTGAG
AAAAGAGGGGTTTAGTAGAGTATTTTTAGCATCAAGTTATGAGGAAGCTGTTAGGGTATTTAGAAATGTAAAGCCAGATT
GTGCAATTTTAGATGTTGTATTGCCAGATGGAGATGGTTTTTCTATTATGAGAAAAATTAGAGAGACATCTAAAATACCA
GTGATTTTTCTCTCTGCAAGAGGTGAAGATGAAGATAGATTGATTGGTTTGGGCTTAGGGGCTGACGATTATATAGTAAA
GCCATTTTTACCAAAGGAACTTACTTTAAGGCTTGTGGGTATATTAAATCGTGTATATGTGCCTATAGAAGAAGAGGAGT
TGCCAGTATTTAAACTGGGAGATTCTGTTGTTGTGAATTTAAATAGTGCATGTGTTGAGAAAGATGGGCAAGAGATTTCT
TTAACAGCTAAAGAGCATTCGTTGCTTTTAAAGTTGTATGAAAATAAAGGGAGAATTGTTACTAATGATTCACTATGTCA
AGCCATTTGGGGAGATGATATGTATGGATATGAAAATACCCTTATGGTTCATGTTAGAAGAGTTAGAGAGAAGATAGAAA
AAACTCCATCTACACCTAAACATCTTATTACAGTAAGAGGTCTTGGATATAAGTTGATGATTAATTAA

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (156-232)

• Response regulator receiver domain (Response_reg) (9-117)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
scnR	Streptococcus mutans UA159	48.918	98.298	0.481
micA	Streptococcus pneumoniae Cp1015	40	100	0.4
vicR	Streptococcus mutans UA159	38.362	98.723	0.379