Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   MGAS9429_RS08710 Genome accession   NC_008021
Coordinates   1768492..1769088 (-) Length   198 a.a.
NCBI ID   WP_002991359.1    Uniprot ID   Q1JJH3
Organism   Streptococcus pyogenes MGAS9429     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1763492..1774088
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MGAS9429_RS08675 (MGAS9429_Spy1806) - 1763553..1763858 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  MGAS9429_RS08680 (MGAS9429_Spy1807) ruvX 1763870..1764289 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  MGAS9429_RS08685 (MGAS9429_Spy1808) - 1764286..1764555 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  MGAS9429_RS08690 (MGAS9429_Spy1809) spx 1764668..1765066 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  MGAS9429_RS08695 (MGAS9429_Spy1810) recA 1765357..1766493 (-) 1137 WP_002982186.1 recombinase RecA Machinery gene
  MGAS9429_RS08700 (MGAS9429_Spy1811) cinA 1766582..1767853 (-) 1272 WP_002991356.1 competence/damage-inducible protein A Machinery gene
  MGAS9429_RS08705 (MGAS9429_Spy1812) - 1767922..1768482 (-) 561 WP_002991358.1 DNA-3-methyladenine glycosylase I -
  MGAS9429_RS08710 (MGAS9429_Spy1813) ruvA 1768492..1769088 (-) 597 WP_002991359.1 Holliday junction branch migration protein RuvA Machinery gene
  MGAS9429_RS08715 (MGAS9429_Spy1814) - 1769090..1770310 (-) 1221 WP_002991361.1 MDR family MFS transporter -
  MGAS9429_RS08720 (MGAS9429_Spy1815) hexB 1770321..1772303 (-) 1983 WP_002991363.1 DNA mismatch repair endonuclease MutL Machinery gene

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 21841.15 Da        Isoelectric Point: 6.2537

>NTDB_id=25681 MGAS9429_RS08710 WP_002991359.1 1768492..1769088(-) (ruvA) [Streptococcus pyogenes MGAS9429]
MYDYIKGQLTKITAKYIVVETNGLGYIINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI
GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGNTKARSNKAGNTQLDEAIEAL
LALGYKATELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide


Download         Length: 597 bp        

>NTDB_id=25681 MGAS9429_RS08710 WP_002991359.1 1768492..1769088(-) (ruvA) [Streptococcus pyogenes MGAS9429]
ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAACAAATGGACTAGGCTATAT
TATCAATGTAGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAACTGGTAACTATTTACCTGCATCAAGTGATTCGTG
AGGATGCTCACTTGTTGTTTGGGTTTCATACGGAAGACGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCTGGCATT
GGCCCCACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA
GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG
CTCCACAAGAGACTGGTAATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC
CTTGCCCTCGGTTATAAGGCAACGGAATTGAAGAAAATTCGTGCCTTCTTTGAAGGAACCTCTGAGACGGCAGAGCAATA
CATCAAATCAGCATTGAAACTGTTAATGAAAGGGTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

RuvA, C-terminal domain (RuvA_C)

(152-196)

Helix-hairpin-helix domain (HHH_5)

(71-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q1JJH3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae TIGR4

67.513

99.495

0.672
  ruvA Streptococcus pneumoniae R6

67.513

99.495

0.672
  ruvA Streptococcus pneumoniae D39

67.513

99.495

0.672
  ruvA Bacillus subtilis subsp. subtilis str. 168

41.379

100

0.424

Multiple sequence alignment