Detailed information NTG0256637

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: CV725_RS03910
• Genome accession: NZ_CP024951
• Coordinates: 777822..778622 (+)
• Length: 266 a.a.
• NCBI ID: WP_000835251.1
• Uniprot ID: D7FF31
• Organism: Helicobacter pylori B128
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 772822..783622

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CV725_RS03875 (CV725_03880)	pseH	773322..773864 (+)	543	WP_000742654.1	UDP-4-amino-4, 6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase	-
CV725_RS03880 (CV725_03885)	-	773797..774735 (-)	939	WP_000833945.1	tetraacyldisaccharide 4'-kinase	-
CV725_RS03885 (CV725_03890)	-	774732..775514 (-)	783	WP_001168242.1	NAD+ synthase	-
CV725_RS03895 (CV725_03900)	ilvC	775763..776755 (+)	993	WP_001207748.1	ketol-acid reductoisomerase	-
CV725_RS03900 (CV725_03905)	minD	776779..777585 (+)	807	WP_001019050.1	septum site-determining protein MinD	-
CV725_RS03905 (CV725_03910)	minE	777582..777815 (+)	234	WP_000051414.1	cell division topological specificity factor MinE	-
CV725_RS03910 (CV725_03915)	dprA	777822..778622 (+)	801	WP_000835251.1	DNA-processing protein DprA	Machinery gene
CV725_RS03915 (CV725_03920)	dprB	778619..779023 (+)	405	WP_000599159.1	Holliday junction resolvase RuvX	Machinery gene
CV725_RS03920 (CV725_03925)	-	779150..779623 (+)	474	WP_013195909.1	tetratricopeptide repeat protein	-
CV725_RS03925 (CV725_03930)	-	779811..780149 (+)	339	WP_000699916.1	hypothetical protein	-
CV725_RS03930 (CV725_03935)	-	780133..780693 (+)	561	WP_000037134.1	hypothetical protein	-
CV725_RS03935 (CV725_03940)	-	780826..781722 (-)	897	WP_001117136.1	RluA family pseudouridine synthase	-
CV725_RS03940 (CV725_03945)	recJ	781722..783272 (-)	1551	WP_000810776.1	single-stranded-DNA-specific exonuclease RecJ	-

Sequence

Protein

• Length: 266 a.a.
• Molecular weight: 29879.74 Da
• Isoelectric Point: 6.9617

>NTDB_id=256637 CV725_RS03910 WP_000835251.1 777822..778622(+) (dprA) [Helicobacter pylori B128]
MKSHFQYSVLENIPKAFDILKDPPKQLYCVGDIKLLEAPLKVAIIGTRRPTPYSKQHTITLARELAKNGAVIVSGGALGV
DIIAQENALPTTIMLSPCSLDFIYPTNNHKVIQEIAQNGLILSEYEKDFMPIKGSFLARNRLVIALSDAVIIPQADLKSG
SMSSARLAQKYQKPLFVLPQRLNESDGTNELLEKGQAQGIFNIQNFINTLLKDYHLKEMPEMEDEFLEYCAKNPSYEEAY
LKFGDKLLEYELLGKIKRINHIVVLA

Nucleotide

• Length: 801 bp

>NTDB_id=256637 CV725_RS03910 WP_000835251.1 777822..778622(+) (dprA) [Helicobacter pylori B128]
ATGAAAAGCCATTTCCAATACAGCGTACTAGAAAATATCCCTAAAGCCTTTGACATACTCAAAGACCCTCCTAAACAGCT
CTATTGTGTGGGCGATATAAAGCTTTTAGAAGCGCCTTTAAAAGTGGCGATCATAGGCACAAGAAGACCCACCCCTTATA
GCAAGCAACACACCATCACTCTAGCCAGAGAGCTTGCTAAAAATGGCGCGGTTATTGTGAGCGGGGGAGCGTTAGGCGTG
GATATTATCGCTCAAGAAAACGCCTTACCAACAACGATCATGCTTTCGCCTTGCAGTTTGGATTTTATCTATCCTACGAA
CAATCATAAAGTGATCCAAGAAATCGCGCAAAACGGCTTGATTTTAAGCGAATATGAAAAGGATTTTATGCCCATTAAAG
GCTCTTTTTTAGCCAGAAACCGCCTGGTGATCGCTTTAAGCGATGCGGTGATTATCCCCCAAGCGGATTTAAAAAGCGGC
TCTATGAGTAGCGCGAGATTAGCCCAAAAATACCAAAAACCCTTGTTTGTTTTACCCCAACGCCTGAATGAAAGCGATGG
CACTAATGAGCTTTTAGAAAAAGGGCAGGCTCAAGGGATATTTAATATTCAAAATTTTATAAACACCCTTTTAAAAGACT
ACCATTTAAAAGAAATGCCTGAAATGGAAGATGAATTTTTAGAATATTGTGCGAAAAACCCTAGCTATGAAGAGGCGTAT
CTCAAATTTGGGGATAAGCTTTTAGAATACGAGCTGTTGGGTAAGATTAAACGCATCAATCATATCGTGGTGTTAGCGTG
A

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (13-197)

3D structure

• AlphaFold DB: D7FF31

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Helicobacter pylori 26695	97.368	100	0.974
dprA	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	48.673	84.962	0.414