Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   CV730_RS00970 Genome accession   NZ_CP024946
Coordinates   198077..198820 (+) Length   247 a.a.
NCBI ID   WP_120832951.1    Uniprot ID   -
Organism   Helicobacter pylori strain B147     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 193077..203820
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CV730_RS00945 (CV730_00940) panD 195244..195588 (+) 345 WP_145728138.1 aspartate 1-decarboxylase -
  CV730_RS00950 (CV730_00945) - 195600..195893 (+) 294 WP_000347917.1 YbaB/EbfC family nucleoid-associated protein -
  CV730_RS00955 (CV730_00950) - 195893..196888 (+) 996 WP_145729126.1 PDZ domain-containing protein -
  CV730_RS00960 (CV730_00955) comB6 196896..197951 (+) 1056 WP_145729124.1 P-type conjugative transfer protein TrbL Machinery gene
  CV730_RS00965 (CV730_00960) comB7 197967..198080 (+) 114 WP_001217873.1 hypothetical protein Machinery gene
  CV730_RS00970 (CV730_00965) comB8 198077..198820 (+) 744 WP_120832951.1 virB8 family protein Machinery gene
  CV730_RS00975 (CV730_00970) comB9 198820..199800 (+) 981 WP_145728139.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  CV730_RS00980 (CV730_00975) comB10 199793..200923 (+) 1131 WP_145728140.1 DNA type IV secretion system protein ComB10 Machinery gene
  CV730_RS00985 (CV730_00980) - 200993..202411 (+) 1419 WP_145728141.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  CV730_RS00990 (CV730_00985) gmd 202421..203566 (+) 1146 WP_145728142.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28767.94 Da        Isoelectric Point: 8.9604

>NTDB_id=256535 CV730_RS00970 WP_120832951.1 198077..198820(+) (comB8) [Helicobacter pylori strain B147]
MREKPFNSEQLIYLEELLSHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAIVLISILPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLTNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKITRYSITEI
APTNRND

Nucleotide


Download         Length: 744 bp        

>NTDB_id=256535 CV730_RS00970 WP_120832951.1 198077..198820(+) (comB8) [Helicobacter pylori strain B147]
ATGAGAGAAAAGCCTTTCAACAGCGAGCAATTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTGTTTCGGTTGGAAAGAAACCGCTTGAAAATCGCTT
ACAAGCTCTTAGGCTTGATGAGTTTTATCGCTCTTGTTTTAGCGATCGTTTTAATCAGTATCCTGCCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGTATTAATCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAGGTGTGGCAACGCTTTGAAGATTTGATTAAAACCCAAAACAGCATTTAT
GCGCAAAGCCATTTAGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
GTCCATTGCAGCTAAACTAACGAACGAAAACAAGCTGGTGTATGAAAAGCGTTATAAAATCGTATTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAATCACTCGCTACAGCATCACTGAAATC
GCACCGACTAACAGGAATGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

97.571

100

0.976

Multiple sequence alignment