Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   SAOUHSC_02098 Genome accession   NC_007795
Coordinates   1972962..1973591 (-) Length   209 a.a.
NCBI ID   YP_500589.1    Uniprot ID   Q2FX09
Organism   Staphylococcus aureus subsp. aureus NCTC 8325     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1967962..1978591
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SAOUHSC_02091 - 1968379..1968909 (-) 531 YP_500583.1 acyl-CoA thioesterase -
  SAOUHSC_02092 - 1968999..1970255 (-) 1257 YP_500584.1 aminopeptidase PepS -
  SAOUHSC_02093 - 1970258..1970458 (-) 201 YP_500585.1 hypothetical protein -
  SAOUHSC_02095 - 1970605..1971069 (+) 465 YP_500586.1 hypothetical protein -
  SAOUHSC_02096 - 1971076..1971351 (+) 276 YP_500587.1 hypothetical protein -
  SAOUHSC_02097 - 1971629..1972846 (+) 1218 YP_500588.1 hypothetical protein -
  SAOUHSC_02098 vraR 1972962..1973591 (-) 630 YP_500589.1 DNA-binding response regulator VraR Regulator
  SAOUHSC_02099 vraS 1973581..1974624 (-) 1044 YP_500590.1 histidine kinase Regulator
  SAOUHSC_02100 - 1974621..1975322 (-) 702 YP_500591.1 hypothetical protein -
  SAOUHSC_02101 - 1975337..1975723 (-) 387 YP_500592.1 hypothetical protein -
  SAOUHSC_02102 - 1975940..1976698 (-) 759 YP_500593.1 methionine aminopeptidase -
  SAOUHSC_02103 - 1977226..1978212 (+) 987 YP_500595.1 hypothetical protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23545.29 Da        Isoelectric Point: 5.3889

>NTDB_id=25457 SAOUHSC_02098 YP_500589.1 1972962..1973591(-) (vraR) [Staphylococcus aureus subsp. aureus NCTC 8325]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMDDMDGVEATTQIKKDLPQIKVL
MLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=25457 SAOUHSC_02098 YP_500589.1 1972962..1973591(-) (vraR) [Staphylococcus aureus subsp. aureus NCTC 8325]
ATGACGATTAAAGTATTGTTTGTGGATGATCATGAAATGGTACGTATAGGAATTTCAAGTTATCTATCAACGCAAAGTGA
TATTGAAGTAGTTGGTGAAGGCGCTTCTGGTAAAGAAGCAATTGCCAAAGCCCATGAGTTGAAGCCAGATTTAATTTTAA
TGGATTTACTTATGGATGACATGGATGGTGTAGAAGCGACGACTCAGATTAAAAAAGATTTACCGCAAATTAAAGTATTA
ATGTTAACTAGTTTTATTGAAGATAAAGAGGTATATCGTGCATTAGATGCAGGTGTCGATAGTTACATTTTAAAAACAAC
AAGTGCAAAAGATATCGCCGATGCAGTTCGTAAAACTTCTAGAGGAGAATCTGTTTTTGAACCGGAAGTTTTAGTGAAAA
TGCGTAACCGTATGAAAAAGCGCGCAGAGTTATATGAAATGCTTACAGAACGAGAAATGGAAATATTATTATTGATTGCG
AAAGGTTACTCAAATCAAGAAATTGCTAGTGCATCGCATATTACTATTAAAACGGTTAAGACACATGTGAGTAACATTTT
AAGTAAGTTAGAAGTGCAAGATAGAACACAAGCTGTTATCTATGCATTCCAACATAATTTAATTCAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 7VE5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

99.522

100

0.995
  degU Bacillus subtilis subsp. subtilis str. 168

34.821

100

0.373

Multiple sequence alignment