Detailed information NTG0025458

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: SAOUHSC_02099
• Genome accession: NC_007795
• Coordinates: 1973581..1974624 (-)
• Length: 347 a.a.
• NCBI ID: YP_500590.1
• Uniprot ID: Q2FX08
• Organism: Staphylococcus aureus subsp. aureus NCTC 8325
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1968581..1979624

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAOUHSC_02092	-	1968999..1970255 (-)	1257	YP_500584.1	aminopeptidase PepS	-
SAOUHSC_02093	-	1970258..1970458 (-)	201	YP_500585.1	hypothetical protein	-
SAOUHSC_02095	-	1970605..1971069 (+)	465	YP_500586.1	hypothetical protein	-
SAOUHSC_02096	-	1971076..1971351 (+)	276	YP_500587.1	hypothetical protein	-
SAOUHSC_02097	-	1971629..1972846 (+)	1218	YP_500588.1	hypothetical protein	-
SAOUHSC_02098	vraR	1972962..1973591 (-)	630	YP_500589.1	DNA-binding response regulator VraR	Regulator
SAOUHSC_02099	vraS	1973581..1974624 (-)	1044	YP_500590.1	histidine kinase	Regulator
SAOUHSC_02100	-	1974621..1975322 (-)	702	YP_500591.1	hypothetical protein	-
SAOUHSC_02101	-	1975337..1975723 (-)	387	YP_500592.1	hypothetical protein	-
SAOUHSC_02102	-	1975940..1976698 (-)	759	YP_500593.1	methionine aminopeptidase	-
SAOUHSC_02103	-	1977226..1978212 (+)	987	YP_500595.1	hypothetical protein	-
SAOUHSC_02104	-	1978643..1979056 (-)	414	YP_500596.1	hypothetical protein	-
SAOUHSC_02105	-	1979085..1979195 (-)	111	YP_500597.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=25458 SAOUHSC_02099 YP_500590.1 1973581..1974624(-) (vraS) [Staphylococcus aureus subsp. aureus NCTC 8325]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=25458 SAOUHSC_02099 YP_500590.1 1973581..1974624(-) (vraS) [Staphylococcus aureus subsp. aureus NCTC 8325]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: Q2FX08

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1