Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   DLJ62_RS02690 Genome accession   NZ_CP029574
Coordinates   489477..490109 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain DA33133     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 484477..495109
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DLJ62_RS02660 (DLJ62_02660) yheS 484646..486559 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  DLJ62_RS02665 (DLJ62_02665) yheT 486559..487581 (+) 1023 WP_044067488.1 hydrolase -
  DLJ62_RS02670 (DLJ62_02670) yheU 487575..487793 (+) 219 WP_000907085.1 YheU family protein -
  DLJ62_RS02675 (DLJ62_02675) prkB 487847..488716 (+) 870 WP_001274680.1 phosphoribulokinase -
  DLJ62_RS02680 (DLJ62_02680) yhfA 488771..489175 (-) 405 WP_001148910.1 OsmC family protein -
  DLJ62_RS02690 (DLJ62_02690) crp 489477..490109 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  DLJ62_RS02695 (DLJ62_02695) yhfK 490160..492250 (+) 2091 WP_001447003.1 YccS/YhfK family putative transporter -
  DLJ62_RS02700 (DLJ62_02700) argD 492316..493536 (-) 1221 WP_000963791.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  DLJ62_RS02705 (DLJ62_02705) pabA 493622..494185 (-) 564 WP_000601854.1 aminodeoxychorismate synthase component 2 -
  DLJ62_RS02710 (DLJ62_02710) fic 494217..494819 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  DLJ62_RS02715 (DLJ62_02715) yhfG 494809..494976 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=254435 DLJ62_RS02690 WP_000242755.1 489477..490109(+) (crp) [Escherichia coli strain DA33133]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=254435 DLJ62_RS02690 WP_000242755.1 489477..490109(+) (crp) [Escherichia coli strain DA33133]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment