Detailed information NTG0254148

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: DLJ52_RS10090
• Genome accession: NZ_CP029559
• Coordinates: 2077538..2080099 (-)
• Length: 853 a.a.
• NCBI ID: WP_109982791.1
• Uniprot ID: -
• Organism: Streptococcus sobrinus strain NIDR 6715-15
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2072538..2085099

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DLJ52_RS10065 (DLJ52_10065)	-	2073061..2073324 (+)	264	WP_109982789.1	hypothetical protein	-
DLJ52_RS10070 (DLJ52_10070)	-	2073374..2073775 (+)	402	WP_019777428.1	helix-turn-helix transcriptional regulator	-
DLJ52_RS10075 (DLJ52_10075)	-	2073809..2074360 (-)	552	WP_002960562.1	DNA-3-methyladenine glycosylase I	-
DLJ52_RS10080 (DLJ52_10080)	ruvA	2074529..2075119 (-)	591	WP_019769153.1	Holliday junction branch migration protein RuvA	Machinery gene
DLJ52_RS10085 (DLJ52_10085)	hexB	2075351..2077297 (-)	1947	WP_109982790.1	DNA mismatch repair endonuclease MutL	Machinery gene
DLJ52_RS10090 (DLJ52_10090)	hexA	2077538..2080099 (-)	2562	WP_109982791.1	DNA mismatch repair protein MutS	Machinery gene
DLJ52_RS10095 (DLJ52_10095)	-	2080086..2080439 (-)	354	WP_019787291.1	YlbF family regulator	-
DLJ52_RS10100 (DLJ52_10100)	argR	2080432..2080866 (-)	435	WP_019775054.1	arginine repressor	-
DLJ52_RS10105 (DLJ52_10105)	argS	2081022..2082713 (+)	1692	WP_109982792.1	arginine--tRNA ligase	-
DLJ52_RS10110 (DLJ52_10110)	-	2082926..2083285 (-)	360	WP_002960574.1	hypothetical protein	-
DLJ52_RS10115 (DLJ52_10115)	-	2083324..2083551 (-)	228	WP_002960575.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
DLJ52_RS10120 (DLJ52_10120)	-	2084120..2085061 (-)	942	WP_019784684.1	YitT family protein	-

Sequence

Protein

• Length: 853 a.a.
• Molecular weight: 95182.31 Da
• Isoelectric Point: 4.7432

>NTDB_id=254148 DLJ52_RS10090 WP_109982791.1 2077538..2080099(-) (hexA) [Streptococcus sobrinus strain NIDR 6715-15]
MAKDKISPGMQQYLDIKESYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLV
DLGYKVAIAEQMEDPKKAVGVVKREVVQVITPGTVVDSSKPDSSNNFLVAIDYLNGVYGLSYMDLSTGEFYATSLTDFTA
VRSEIQNLKAKEVVLGFDLSDKQQEALTKQMSLLLSPEKEVYDDVQLIGSDLSSVEAQAAGKLLQYVHQTQKRELSHLQS
LVHYEIKDFLQMTYATKTSLDLLENARSSKKHGSLFWLLDSTKTAMGMRLLRTWIDRPLVSQEKILERQEIVQTFLDNFF
ERSDLTDSLKGVYDIERLASRVSFGKANPKDLLQLGHTLAQVPKIKTMLASFASPVLDRLNEAIDALPELESLIASAIDQ
DAPATITEGGMIKIGFDQQLDHYRQVMREGTTWIAEIEAKERAASGISTLKIDYNRKDGYYFHVTNSNLSLVPDHFFRKA
TLKNSERFGTAELAKIEGDMLEAREQSATLEYDIFMTVRNQVEKYIQRLQDLAKNIATVDALQSLAVVAENNHYVRPQFN
DQEVIDIQDGRHAVVEKVMGTQEYIPNTITLDQDTAIQLITGPNMSGKSTYMRQLALTVVMAQIGSFVAAESANLPIFDA
IYTRIGAADDLISGQSTFMVEMMEANMAIQRASSQSLILFDELGRGTATYDGMALAQAIIEHIHDQVGAKTFFATHYHEL
TELSTSLTHLVNVHVATLEKDGDVTFLHKITAGPADKSYGVHVAKIAGLPEALLQRANAILTDLEAHSVSLTGQEDFTEL
DKPIKQKRDSQQLSLFEVAEPNDKLVQALQDLDVVNMTPMEAMNALFELKKLL

Nucleotide

• Length: 2562 bp

>NTDB_id=254148 DLJ52_RS10090 WP_109982791.1 2077538..2080099(-) (hexA) [Streptococcus sobrinus strain NIDR 6715-15]
ATGGCAAAAGATAAAATTTCTCCAGGCATGCAGCAGTATTTAGACATCAAAGAATCCTATCCGGATGCTTTTTTGCTTTT
TCGGATGGGGGATTTTTATGAGCTCTTCTACGACGATGCGGTTAAGGCTGCTCAGATTTTGGAAATCAGCCTCACCAGTC
GCAATAAGAATGCTGACAATCCCATTCCTATGGCGGGCGTGCCCTATCATTCAGCACAACAATATATTGATGTCCTAGTC
GATTTGGGTTATAAGGTGGCCATTGCCGAGCAGATGGAGGACCCCAAAAAGGCTGTTGGTGTCGTCAAACGGGAGGTTGT
TCAGGTGATTACGCCAGGAACCGTGGTGGATTCCAGCAAGCCCGATAGCAGTAATAATTTCTTGGTTGCCATCGACTATC
TGAATGGGGTTTACGGACTCTCCTATATGGACCTCTCAACTGGGGAGTTTTACGCCACCAGCCTGACAGACTTTACAGCC
GTTCGTAGCGAAATTCAAAATCTCAAGGCCAAGGAAGTCGTTCTGGGCTTTGATTTGAGTGACAAGCAGCAGGAAGCTCT
GACCAAGCAGATGAGTCTCCTTTTGTCACCTGAAAAAGAGGTCTATGATGATGTCCAGCTGATTGGCTCTGACTTGTCAA
GCGTAGAGGCCCAGGCCGCTGGTAAGCTCCTCCAATACGTCCATCAGACACAAAAGCGGGAGCTCAGCCACCTACAAAGT
CTGGTTCACTACGAAATCAAGGACTTCCTGCAGATGACCTATGCCACCAAGACCAGTCTGGATCTCTTGGAAAATGCTAG
AAGCAGCAAGAAGCACGGCAGTCTCTTCTGGCTTTTGGATTCAACTAAGACAGCCATGGGGATGCGGCTCTTGCGGACCT
GGATTGATCGGCCCTTGGTTAGCCAAGAGAAAATCTTGGAGCGGCAGGAGATTGTTCAGACCTTCTTGGATAACTTTTTT
GAACGCAGCGACCTGACCGACAGCCTCAAGGGCGTCTATGATATTGAACGCCTGGCCAGCCGAGTGTCTTTTGGTAAGGC
CAATCCCAAGGACCTCTTGCAGTTGGGGCATACTCTAGCCCAGGTTCCCAAAATCAAGACCATGTTGGCTAGCTTTGCTA
GCCCAGTTTTAGACCGGCTAAATGAAGCCATTGATGCCCTGCCGGAGTTGGAAAGTCTGATTGCCTCGGCCATTGACCAA
GATGCTCCAGCCACCATTACCGAAGGGGGCATGATTAAGATAGGCTTTGACCAGCAGTTGGATCATTATCGCCAGGTGAT
GCGGGAAGGAACCACCTGGATTGCCGAAATCGAAGCCAAGGAGCGAGCAGCCAGCGGGATTTCCACCCTCAAGATTGATT
ACAACCGCAAGGATGGTTACTATTTCCATGTGACCAATTCCAATCTTTCCCTAGTGCCGGACCATTTCTTCCGCAAGGCA
ACTCTGAAAAATTCTGAGCGGTTTGGAACTGCTGAACTAGCCAAAATTGAAGGTGATATGCTGGAAGCGAGGGAGCAATC
GGCAACCCTTGAGTACGATATCTTTATGACCGTCCGCAATCAGGTGGAAAAATACATCCAGCGCCTGCAAGACCTGGCTA
AAAATATTGCAACTGTGGATGCTCTGCAAAGTCTAGCTGTTGTCGCTGAAAACAATCATTATGTGCGACCCCAGTTCAAT
GACCAAGAGGTCATTGACATTCAAGACGGTCGCCATGCTGTTGTCGAAAAGGTCATGGGAACCCAGGAATACATCCCCAA
CACCATAACCTTAGACCAGGATACCGCTATTCAGCTGATTACGGGTCCTAATATGAGTGGGAAATCCACCTATATGCGCC
AGCTAGCCCTGACTGTTGTTATGGCCCAAATTGGCTCCTTTGTGGCCGCTGAGTCAGCCAATTTGCCAATTTTTGATGCT
ATCTATACACGGATTGGGGCAGCTGATGACCTGATTTCTGGTCAATCCACCTTCATGGTTGAGATGATGGAGGCCAACAT
GGCCATCCAGCGGGCCAGCAGTCAGTCCCTTATCCTCTTTGATGAATTGGGTCGAGGCACCGCCACCTATGACGGAATGG
CTCTAGCTCAAGCCATTATCGAACACATTCACGACCAGGTAGGGGCTAAGACCTTCTTCGCCACCCACTATCATGAGTTG
ACAGAACTGTCAACTAGCTTGACACACCTAGTTAATGTTCATGTAGCGACTCTGGAAAAGGATGGGGATGTCACCTTCCT
GCATAAGATTACAGCTGGTCCTGCTGACAAGTCTTACGGGGTTCATGTGGCCAAGATTGCAGGTTTGCCTGAGGCTCTCC
TCCAGCGAGCCAATGCTATCTTGACTGATTTAGAGGCCCATTCGGTCAGCTTAACCGGCCAAGAAGACTTTACAGAGCTT
GACAAACCTATCAAACAGAAAAGAGACAGTCAACAGTTGTCCCTCTTTGAAGTAGCAGAACCTAATGATAAGTTGGTTCA
AGCCCTCCAAGACCTTGATGTGGTCAATATGACCCCTATGGAAGCCATGAATGCCCTTTTTGAGTTGAAAAAATTGTTGT
AA

Domains

Predicted by InterProScan.

• MutS domain V (MutS_V) (599-785)

• MutS domain II (MutS_II) (126-239)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain I (MutS_I) (8-118)

• MutS domain III (MutS_III) (256-546)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	72.014	100	0.721
mutS	Pseudomonas stutzeri strain ATCC 17587	38.662	94.607	0.366