Detailed information NTG0253683

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DKK89_RS12575
• Genome accession: NZ_CP029474
• Coordinates: 2478382..2479371 (-)
• Length: 329 a.a.
• NCBI ID: WP_000219066.1
• Uniprot ID: P67655
• Organism: Staphylococcus aureus strain USA 100 isolate 30-47
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 2473382..2484371

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DKK89_RS12560 (DKK89_12550)	acsA	2474583..2476289 (-)	1707	WP_000862096.1	acetate--CoA ligase	-
DKK89_RS12565 (DKK89_12555)	-	2476458..2477090 (+)	633	WP_001016004.1	hypothetical protein	-
DKK89_RS12570 (DKK89_12560)	-	2477115..2478284 (+)	1170	WP_001184015.1	acetoin utilization protein AcuC	-
DKK89_RS12575 (DKK89_12565)	ccpA	2478382..2479371 (-)	990	WP_000219066.1	catabolite control protein A	Regulator
DKK89_RS12580 (DKK89_12570)	-	2479444..2479557 (-)	114	WP_001788994.1	hypothetical protein	-
DKK89_RS12585 (DKK89_12575)	-	2479911..2481002 (-)	1092	WP_000066378.1	bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase	-
DKK89_RS12590 (DKK89_12580)	-	2481457..2481540 (-)	84	WP_031761406.1	hypothetical protein	-
DKK89_RS12595 (DKK89_12585)	-	2481696..2483054 (-)	1359	WP_000193903.1	hypothetical protein	-
DKK89_RS12600 (DKK89_12590)	-	2483128..2483619 (-)	492	WP_000383814.1	DUF948 domain-containing protein	-

Sequence

Protein

• Length: 329 a.a.
• Molecular weight: 36060.24 Da
• Isoelectric Point: 5.5054

>NTDB_id=253683 DKK89_RS12575 WP_000219066.1 2478382..2479371(-) (ccpA) [Staphylococcus aureus strain USA 100 isolate 30-47]
MTVTIYDVAREARVSMATVSRVVNGNQNVKAETKNKVNEVIKRLNYRPNAVARGLASKKTTTVGVIIPDISNIYYSQLAR
GLEDIATMYKYHSIISNSDNDPEKEKEIFNNLLSKQVDGIIFLGGTITEEMKELINQSSVPVVVSGTNGKDAHIASVNID
FTEAAKEITGELIEKGAKSFALVGGEHSKKAQEDVLEGLTEVLNKNGLQLGDTLNCSGAESYKEGVKAFAKMKGNLPDAI
LCISDEEAIGIMHSAMDAGIKVPEELQIISFNNTRLVEMVRPQLSSVIQPLYDIGAVGMRLLTKYMNDEKIEEPNVVLPH
RIEYRGTTK

Nucleotide

• Length: 990 bp

>NTDB_id=253683 DKK89_RS12575 WP_000219066.1 2478382..2479371(-) (ccpA) [Staphylococcus aureus strain USA 100 isolate 30-47]
ATGACAGTTACTATATATGATGTAGCAAGAGAAGCGCGTGTCTCTATGGCCACAGTGTCGCGTGTTGTTAATGGGAACCA
AAATGTTAAAGCAGAAACTAAAAATAAAGTTAACGAAGTCATTAAGCGTTTGAATTATCGTCCAAATGCTGTTGCTAGAG
GTTTAGCTAGTAAAAAGACAACAACAGTAGGTGTGATCATTCCAGATATATCTAATATCTATTATTCACAACTTGCTCGT
GGACTTGAAGATATTGCAACAATGTATAAATATCACTCAATTATTTCAAATTCAGATAACGATCCTGAAAAGGAAAAAGA
AATTTTTAATAACTTATTAAGTAAACAGGTTGATGGTATTATTTTCCTTGGTGGTACAATTACTGAAGAAATGAAAGAAT
TGATAAATCAATCATCTGTACCTGTAGTAGTATCAGGAACAAATGGTAAGGATGCACATATAGCATCAGTTAATATTGAT
TTTACTGAAGCTGCGAAAGAAATTACGGGAGAATTAATTGAAAAAGGCGCTAAATCATTTGCTTTAGTAGGTGGAGAACA
TTCTAAAAAAGCTCAAGAAGATGTTTTAGAAGGTTTAACTGAAGTGTTAAATAAAAATGGCCTTCAATTAGGTGATACAT
TGAATTGTTCTGGTGCTGAAAGTTATAAAGAAGGCGTAAAAGCTTTTGCTAAAATGAAAGGCAATTTGCCAGATGCCATT
TTATGTATCAGCGACGAAGAAGCAATTGGTATTATGCATAGTGCAATGGATGCTGGTATTAAAGTTCCAGAGGAATTACA
AATTATTAGTTTCAATAATACACGATTAGTTGAGATGGTTAGACCACAACTTTCTAGTGTTATTCAACCATTATATGATA
TCGGTGCAGTAGGGATGCGCTTATTAACAAAATATATGAACGATGAAAAGATAGAAGAACCAAATGTAGTTTTACCTCAC
AGAATTGAATACCGAGGAACTACAAAATAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (4-49)

• Periplasmic binding protein-like domain (Peripla_BP_3) (171-328)

3D structure

• AlphaFold DB: P67655

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	47.879	100	0.48
ccpA	Streptococcus gordonii str. Challis substr. CH1	47.112	100	0.471
ccpA	Streptococcus pneumoniae D39	46.201	100	0.462