Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   DEH18_RS31575 Genome accession   NZ_CP029241
Coordinates   7874335..7875456 (+) Length   373 a.a.
NCBI ID   WP_030889310.1    Uniprot ID   A0A4Y3RAD5
Organism   Streptomyces sp. NHF165     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 7869335..7880456
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DEH18_RS31565 (DEH18_32030) - 7870470..7872437 (-) 1968 WP_159789250.1 hypothetical protein -
  DEH18_RS31570 (DEH18_32035) radA/sms 7872730..7874136 (+) 1407 WP_030889307.1 DNA repair protein RadA Machinery gene
  DEH18_RS31575 (DEH18_32045) disA 7874335..7875456 (+) 1122 WP_030889310.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  DEH18_RS31580 (DEH18_32050) - 7875534..7876400 (-) 867 WP_030889313.1 hypothetical protein -
  DEH18_RS31585 (DEH18_32055) - 7876628..7877617 (+) 990 WP_030889317.1 A/G-specific adenine glycosylase -
  DEH18_RS31590 (DEH18_32060) - 7877837..7879339 (-) 1503 WP_051847037.1 MDR family MFS transporter -
  DEH18_RS31595 (DEH18_32065) - 7879596..7880165 (+) 570 WP_030889323.1 TetR/AcrR family transcriptional regulator -

Sequence

Protein


Download         Length: 373 a.a.        Molecular weight: 40134.97 Da        Isoelectric Point: 5.1039

>NTDB_id=252389 DEH18_RS31575 WP_030889310.1 7874335..7875456(+) (disA) [Streptomyces sp. NHF165]
MAANDRAAVPGRAEGASGLMRASLSAVAPGTALRDGLERVLRGNTGGLIVLGMDKTVEALCTGGFVLDVDFSATRLRELC
KLDGALILDKDISKIVRAGVQLVPDASIETEETGTRHRTAQRVSIQTGFPVVSVSQSMRLIALYVEGQRRVLEDSAAILS
RANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELIAGVE
PERELVVRDYVPQTGGSGRRVRTVPEALSELDRLSHSELLELPTVARALGYSGAPETLDSAVSPRGFRLLAKVPRLPGTI
IDRLVDHFGGLQKLLAASVDDLQAVEGVGEARARSVREGLSRLAESSILERYV

Nucleotide


Download         Length: 1122 bp        

>NTDB_id=252389 DEH18_RS31575 WP_030889310.1 7874335..7875456(+) (disA) [Streptomyces sp. NHF165]
GTGGCAGCCAACGACCGGGCAGCGGTCCCCGGCAGGGCCGAGGGGGCGTCCGGCCTGATGCGCGCCTCGCTGAGCGCGGT
GGCGCCCGGCACGGCCCTGCGGGACGGGCTGGAGAGGGTTCTGCGCGGGAACACCGGCGGGCTCATCGTCCTCGGCATGG
ACAAGACCGTCGAAGCCCTGTGCACCGGCGGCTTCGTGCTCGATGTGGACTTCAGCGCGACCCGCCTGCGGGAACTGTGC
AAGCTGGACGGGGCGCTCATCCTCGACAAGGACATCTCGAAGATCGTCCGCGCCGGTGTGCAGCTCGTGCCGGACGCCTC
CATCGAGACGGAGGAGACCGGCACCCGGCACCGCACGGCGCAGCGCGTCTCCATCCAGACGGGTTTCCCCGTGGTCTCCG
TCAGCCAGTCGATGCGGCTGATCGCCCTCTATGTGGAGGGCCAGCGCCGCGTCCTGGAGGACTCGGCGGCGATCCTCTCC
CGCGCCAACCAGGCCCTGGCCACCCTGGAGCGCTACAAGCTGCGGCTGGACGAGGTGGCCGGCACCCTCTCGGCGCTGGA
GATCGAGGATCTGGTGACGGTCCGGGACGTCACCGCCGTCGCCCAGCGGCTGGAGATGGTGCGGCGGATCGCCACGGAGA
TCGCCGAGTACGTCGTCGAACTGGGCACGGACGGGCGGTTGCTCTCCCTTCAGCTCGACGAGCTGATCGCGGGCGTCGAG
CCCGAGCGGGAACTGGTCGTCCGCGACTACGTGCCGCAGACGGGCGGTTCGGGCCGGCGGGTGCGCACCGTGCCCGAGGC
ACTCAGCGAACTGGACCGGCTCTCCCACTCCGAGCTGCTCGAACTGCCCACCGTGGCCCGCGCCCTGGGCTACAGCGGTG
CGCCCGAGACGCTGGACTCGGCGGTCTCGCCGCGCGGCTTCCGGCTGCTGGCCAAGGTGCCGCGGCTGCCGGGGACGATC
ATCGACCGGCTCGTGGACCACTTCGGCGGCCTGCAAAAGCTGCTCGCCGCCAGCGTGGACGATCTCCAGGCCGTGGAGGG
CGTGGGCGAGGCCCGGGCCCGCTCGGTCCGTGAGGGCCTCTCGCGCCTCGCCGAGTCGTCCATCCTCGAACGCTACGTCT
GA

Domains

Predicted by InterProScan.

DisA bacterial checkpoint controller linker region (DisA-linker)

(152-295)

Helix-hairpin-helix motif (HHH)

(331-358)

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(35-148)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4Y3RAD5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

46.839

93.298

0.437

Multiple sequence alignment