Detailed information NTG0252073

Bioinformatically predicted

Overview

• Name: comD/blpH
• Type: Regulator
• Locus tag: DEH83_RS01475
• Genome accession: NZ_CP029207
• Coordinates: 308454..309365 (+)
• Length: 303 a.a.
• NCBI ID: WP_255776892.1
• Uniprot ID: -
• Organism: Streptococcus constellatus strain TCV107
• Function: phosphorylation of ComE; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 303454..314365

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DEH83_RS01435 (DEH83_01410)	-	303529..303747 (-)	219	WP_021002958.1	Blp family class II bacteriocin	-
DEH83_RS01440 (DEH83_01415)	-	303922..304242 (-)	321	WP_049476579.1	hypothetical protein	-
DEH83_RS01445 (DEH83_01420)	-	304392..304682 (-)	291	WP_006267076.1	bacteriocin immunity protein	-
DEH83_RS01450 (DEH83_01425)	-	304734..304967 (-)	234	WP_003025420.1	garvicin Q family class II bacteriocin	-
DEH83_RS01455 (DEH83_01430)	-	304975..305295 (-)	321	WP_006267159.1	hypothetical protein	-
DEH83_RS01460 (DEH83_01440)	-	305972..306193 (-)	222	WP_006267535.1	Blp family class II bacteriocin	-
DEH83_RS01465 (DEH83_01445)	-	306425..307138 (+)	714	WP_020997680.1	CPBP family intramembrane glutamic endopeptidase	-
DEH83_RS01470 (DEH83_01450)	comE/blpR	307307..308053 (+)	747	WP_255776891.1	response regulator transcription factor	Regulator
DEH83_RS01475 (DEH83_01455)	comD/blpH	308454..309365 (+)	912	WP_255776892.1	sensor histidine kinase	Regulator
DEH83_RS01480 (DEH83_01460)	-	309410..309559 (-)	150	WP_003025431.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
DEH83_RS01485 (DEH83_01465)	-	309653..311014 (-)	1362	WP_255776893.1	bacteriocin secretion accessory protein	-
DEH83_RS01490 (DEH83_01470)	comA/nlmT	311025..313175 (-)	2151	WP_255776894.1	peptide cleavage/export ABC transporter	Regulator
DEH83_RS01495 (DEH83_01480)	-	313658..314032 (+)	375	WP_255776895.1	hypothetical protein	-

Sequence

Protein

• Length: 303 a.a.
• Molecular weight: 34975.34 Da
• Isoelectric Point: 6.9372

>NTDB_id=252073 DEH83_RS01475 WP_255776892.1 308454..309365(+) (comD/blpH) [Streptococcus constellatus strain TCV107]
MRLIQYNFKTLKSQKINHNDKKIIIFVNISMIVYHLIVQVLSYLENESNIQTLNFRESLVVLYLILFVSVANYLDRHLRE
RIQNDLMLQKDLQLKNMENYSHHIEELYTEVRNFRHDYENILMTLKLGIEQNNLGIVKNVYHSVLKDSNKRFRNPKYDIG
LLVHIKNEALKSLLAAKFAQAQEHNVAVSLEVPEDIYPQGMELVDFITIVSILCDNAIEAAAPTMTIAYVLSENKQVFSI
ENTIKEEHIDMSRIFDAGVSSKGAGRGIGLSNVLAILDRYPNVSLTSASQNYRFQHVLEIHLN

Nucleotide

• Length: 912 bp

>NTDB_id=252073 DEH83_RS01475 WP_255776892.1 308454..309365(+) (comD/blpH) [Streptococcus constellatus strain TCV107]
TTGCGTTTAATTCAATATAATTTTAAGACATTAAAATCTCAAAAAATTAATCACAACGATAAGAAAATTATCATCTTTGT
AAATATCAGCATGATTGTTTATCATCTTATTGTTCAAGTTCTATCTTATTTAGAAAACGAGAGTAACATACAGACACTAA
ATTTTAGAGAAAGTTTAGTAGTTCTTTATCTTATCCTTTTTGTGAGTGTTGCTAATTATTTAGACCGTCATTTACGAGAG
AGAATCCAAAATGATTTAATGCTTCAAAAAGATTTACAGTTAAAAAATATGGAAAACTACAGTCATCACATTGAAGAACT
GTACACAGAAGTTCGGAATTTTCGGCATGATTACGAAAATATTTTAATGACCTTAAAATTAGGAATTGAACAAAATAATC
TAGGTATTGTAAAGAATGTATATCATTCTGTTTTGAAAGATTCCAATAAGCGCTTTCGCAATCCCAAGTATGATATCGGA
CTGTTAGTCCATATCAAAAATGAAGCTTTAAAGAGCCTGCTAGCTGCTAAATTTGCACAAGCTCAAGAGCATAATGTAGC
CGTTTCATTGGAGGTTCCAGAAGATATTTACCCGCAAGGAATGGAATTAGTTGACTTTATCACCATTGTCTCCATTTTGT
GTGATAATGCTATTGAAGCTGCTGCTCCAACTATGACGATTGCTTATGTTTTGTCAGAAAACAAGCAGGTATTCTCCATT
GAAAATACTATAAAAGAGGAACATATAGACATGTCTCGTATTTTTGATGCAGGAGTTAGTTCTAAAGGAGCTGGGCGAGG
AATTGGATTATCAAATGTCTTAGCAATTCTGGATAGGTACCCAAATGTTTCTCTTACTAGCGCTAGTCAAAATTATCGTT
TCCAGCATGTCCTTGAGATTCATCTGAATTAA

Domains

Predicted by InterProScan.

• GHKL domain (HATPase_c_5) (201-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comD/blpH	Streptococcus mutans UA159	43.31	93.729	0.406
comD/comD3	Streptococcus equinus JB1	37.793	98.68	0.373