Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CSC22_RS23705 Genome accession   NZ_CP029115
Coordinates   4435356..4435988 (+) Length   210 a.a.
NCBI ID   WP_000242761.1    Uniprot ID   -
Organism   Escherichia coli strain AR435     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4430356..4440988
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CSC22_RS23675 (CSC22_4502) yheS 4430525..4432438 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  CSC22_RS23680 (CSC22_4503) yheT 4432438..4433460 (+) 1023 WP_000057356.1 hydrolase -
  CSC22_RS23685 (CSC22_4504) yheU 4433454..4433672 (+) 219 WP_000907085.1 YheU family protein -
  CSC22_RS23690 (CSC22_4505) prkB 4433726..4434595 (+) 870 WP_001274680.1 phosphoribulokinase -
  CSC22_RS23695 (CSC22_4506) yhfA 4434650..4435054 (-) 405 WP_001148908.1 OsmC family protein -
  CSC22_RS23705 (CSC22_4507) crp 4435356..4435988 (+) 633 WP_000242761.1 cAMP-activated global transcriptional regulator CRP Regulator
  CSC22_RS23710 (CSC22_4508) yhfK 4436039..4438129 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  CSC22_RS23715 (CSC22_4509) argD 4438196..4439416 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  CSC22_RS23720 (CSC22_4510) pabA 4439502..4440065 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  CSC22_RS23725 (CSC22_4511) fic 4440097..4440699 (-) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  CSC22_RS23730 (CSC22_4512) yhfG 4440689..4440856 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23644.41 Da        Isoelectric Point: 8.2710

>NTDB_id=251580 CSC22_RS23705 WP_000242761.1 4435356..4435988(+) (crp) [Escherichia coli strain AR435]
MVLGKTQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=251580 CSC22_RS23705 WP_000242761.1 4435356..4435988(+) (crp) [Escherichia coli strain AR435]
ATGGTGCTTGGCAAAACGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.238

100

0.952
  crp Haemophilus influenzae Rd KW20

78.049

97.619

0.762
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467