Detailed information NTG0251415

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: CR541_RS00820
• Genome accession: NZ_CP024050
• Coordinates: 122461..122895 (+)
• Length: 144 a.a.
• NCBI ID: WP_011922561.1
• Uniprot ID: -
• Organism: Streptococcus suis strain CS100322
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 117461..127895

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CR541_RS00785 (CR541_00785)	-	118210..118575 (+)	366	WP_002936568.1	DUF1033 family protein	-
CR541_RS00790 (CR541_00790)	-	118610..119553 (-)	944	Protein_115	S66 peptidase family protein	-
CR541_RS00795 (CR541_00795)	comYA	119639..120589 (+)	951	WP_011921718.1	competence type IV pilus ATPase ComGA	Machinery gene
CR541_RS00800 (CR541_00800)	comYB	120501..121538 (+)	1038	WP_011921719.1	competence type IV pilus assembly protein ComGB	Machinery gene
CR541_RS00805 (CR541_00805)	comYC	121540..121821 (+)	282	WP_011921720.1	competence type IV pilus major pilin ComGC	Machinery gene
CR541_RS00810 (CR541_00810)	comGD	121802..122209 (+)	408	WP_011921721.1	competence type IV pilus minor pilin ComGD	-
CR541_RS00815 (CR541_00815)	comYE	122181..122474 (+)	294	WP_011921722.1	competence type IV pilus minor pilin ComGE	Machinery gene
CR541_RS00820 (CR541_00820)	comGF/cglF	122461..122895 (+)	435	WP_011922561.1	competence type IV pilus minor pilin ComGF	Machinery gene
CR541_RS00825 (CR541_00825)	comGG	122873..123283 (+)	411	WP_011921724.1	competence type IV pilus minor pilin ComGG	-
CR541_RS00830 (CR541_00830)	comYH	123340..124293 (+)	954	WP_011922562.1	class I SAM-dependent methyltransferase	Machinery gene
CR541_RS00835 (CR541_00835)	-	124343..125530 (+)	1188	WP_012775422.1	acetate kinase	-
CR541_RS00840 (CR541_00840)	-	125845..126396 (+)	552	WP_012774908.1	folate family ECF transporter S component	-
CR541_RS00845 (CR541_00845)	-	126452..127708 (+)	1257	WP_011921729.1	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16491.85 Da
• Isoelectric Point: 5.9234

>NTDB_id=251415 CR541_RS00820 WP_011922561.1 122461..122895(+) (comGF/cglF) [Streptococcus suis strain CS100322]
MLKSKIPAFTLLECLVVLVILSGSLLIFEGLSKLLVQEAHYQGQTVQKEWLVFSSQLRSEWDQAELVKVENGKVYVNKGE
QALAFGKSWSDDFRKTNDRGQGYQPMLYQVDSAAISQENQLVRIDFSFKNGEERTFIYAFKEKS

Nucleotide

• Length: 435 bp

>NTDB_id=251415 CR541_RS00820 WP_011922561.1 122461..122895(+) (comGF/cglF) [Streptococcus suis strain CS100322]
TTGTTAAAAAGTAAAATTCCTGCTTTTACACTCTTGGAATGTTTGGTGGTTCTAGTCATTCTGTCAGGTAGCCTCTTGAT
TTTTGAAGGCTTATCCAAATTACTAGTCCAGGAAGCGCATTATCAAGGTCAGACCGTTCAAAAGGAATGGTTGGTCTTCT
CTAGCCAATTGCGGTCGGAGTGGGACCAGGCTGAATTGGTCAAGGTTGAAAATGGCAAGGTCTATGTCAACAAAGGTGAA
CAGGCTTTGGCCTTTGGCAAGTCATGGTCGGATGATTTTCGGAAAACAAATGATAGAGGCCAGGGTTACCAACCCATGCT
CTATCAGGTGGATAGCGCAGCCATTTCCCAAGAAAACCAGCTGGTGCGCATCGACTTTAGCTTTAAAAACGGAGAGGAGC
GAACCTTTATCTATGCTTTTAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (37-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae TIGR4	52.482	97.917	0.514
comGF/cglF	Streptococcus pneumoniae Rx1	52.482	97.917	0.514
comGF/cglF	Streptococcus pneumoniae D39	52.482	97.917	0.514
comGF/cglF	Streptococcus pneumoniae R6	52.482	97.917	0.514
comGF/cglF	Streptococcus mitis NCTC 12261	52.985	93.056	0.493
comYF	Streptococcus mutans UA140	48.611	100	0.486
comYF	Streptococcus mutans UA159	47.917	100	0.479
comGF/cglF	Streptococcus mitis SK321	50	93.056	0.465
comGF	Lactococcus lactis subsp. cremoris KW2	45.39	97.917	0.444