Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   CRN64_RS11995 Genome accession   NZ_CP023970
Coordinates   2512993..2513622 (+) Length   209 a.a.
NCBI ID   WP_002461333.1    Uniprot ID   -
Organism   Staphylococcus lugdunensis strain FDAARGOS_381     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2507993..2518622
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CRN64_RS11970 (CRN64_11970) - 2508746..2509726 (-) 981 WP_002492696.1 aromatic acid exporter family protein -
  CRN64_RS11975 (CRN64_11975) map 2509970..2510725 (+) 756 WP_002461338.1 type I methionyl aminopeptidase -
  CRN64_RS11980 (CRN64_11980) - 2510851..2511237 (+) 387 WP_002477960.1 hypothetical protein -
  CRN64_RS11985 (CRN64_11985) liaF 2511262..2511963 (+) 702 WP_002461335.1 cell wall-active antibiotics response protein LiaF -
  CRN64_RS11990 (CRN64_11990) vraS 2511960..2513003 (+) 1044 WP_002461334.1 sensor histidine kinase Regulator
  CRN64_RS11995 (CRN64_11995) vraR 2512993..2513622 (+) 630 WP_002461333.1 two-component system response regulator VraR Regulator
  CRN64_RS12000 (CRN64_12000) - 2513795..2515024 (-) 1230 WP_002492699.1 YihY/virulence factor BrkB family protein -
  CRN64_RS12005 (CRN64_12005) - 2515227..2515511 (-) 285 WP_002461330.1 YtxH domain-containing protein -
  CRN64_RS12010 (CRN64_12010) - 2515518..2515982 (-) 465 WP_002492719.1 low molecular weight protein-tyrosine-phosphatase -
  CRN64_RS12015 (CRN64_12015) - 2516146..2516331 (+) 186 WP_002492715.1 DUF1128 domain-containing protein -
  CRN64_RS12020 (CRN64_12020) - 2516344..2517582 (+) 1239 WP_002461326.1 aminopeptidase -
  CRN64_RS12025 (CRN64_12025) - 2517616..2518143 (+) 528 WP_002461325.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23658.47 Da        Isoelectric Point: 5.3841

>NTDB_id=251054 CRN64_RS11995 WP_002461333.1 2512993..2513622(+) (vraR) [Staphylococcus lugdunensis strain FDAARGOS_381]
MTIKVLFVDDHEMVRIGISSYLSTQPDLEVVGEGASGKEAIAKAQELKPDLILMDLLMEDMDGVEATTQIKKEMPHIKVV
MLTSFIEDKEVYRALDAGVDSYILKTTSAKDIAEAVRKTYHGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=251054 CRN64_RS11995 WP_002461333.1 2512993..2513622(+) (vraR) [Staphylococcus lugdunensis strain FDAARGOS_381]
ATGACAATTAAAGTACTATTTGTAGATGACCATGAAATGGTAAGAATAGGAATTTCTAGTTATTTATCTACTCAACCAGA
CCTTGAAGTTGTAGGTGAAGGTGCTTCTGGTAAAGAGGCAATAGCTAAAGCACAAGAATTAAAGCCAGATTTAATCTTGA
TGGATTTATTAATGGAAGACATGGATGGCGTCGAAGCGACAACACAAATCAAGAAAGAGATGCCTCATATTAAAGTTGTA
ATGCTGACTAGCTTTATTGAGGATAAAGAAGTATATAGAGCGTTAGACGCTGGTGTTGACAGCTATATTTTAAAAACAAC
AAGCGCTAAAGATATCGCTGAAGCAGTGCGCAAAACATATCATGGAGAATCTGTATTTGAACCGGAAGTTCTGGTAAAAA
TGCGAAATAGAATGAAAAAACGTGCAGAGCTATATGAAATGTTAACAGAACGAGAAATGGAAATTTTACTGTTAATTGCT
AAAGGATATTCTAATCAAGAAATCGCAAGCGCATCACACATTACTATTAAAACAGTTAAAACACATGTGAGTAATATTTT
AAGCAAATTAGAAGTACAAGACCGTACACAAGCAGTAATCTATGCATTTCAGCATAATCTTATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

95.215

100

0.952
  degU Bacillus subtilis subsp. subtilis str. 168

35.714

100

0.383

Multiple sequence alignment