Detailed information NTG0249829

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: CRD75_RS02275
• Genome accession: NZ_CP023769
• Coordinates: 417842..418843 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain HarveyGAS
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 412842..423843

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CRD75_RS02250 (CRD75_02250)	-	413516..414199 (-)	684	WP_011017476.1	DUF969 domain-containing protein	-
CRD75_RS02255 (CRD75_02255)	-	414410..415336 (-)	927	WP_011017477.1	glycosyltransferase family 2 protein	-
CRD75_RS02260 (CRD75_02260)	-	415481..415858 (-)	378	WP_002985686.1	VOC family protein	-
CRD75_RS02265 (CRD75_02265)	-	415869..416534 (-)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
CRD75_RS02270 (CRD75_02270)	-	416583..417668 (-)	1086	WP_011284589.1	Xaa-Pro peptidase family protein	-
CRD75_RS02275 (CRD75_02275)	ccpA	417842..418843 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
CRD75_RS02280 (CRD75_02280)	-	418974..419972 (+)	999	WP_002990703.1	glycosyltransferase family 4 protein	-
CRD75_RS02285 (CRD75_02285)	-	419974..421308 (+)	1335	WP_011284590.1	glycosyltransferase family 4 protein	-
CRD75_RS02290 (CRD75_02290)	thrS	421730..423673 (+)	1944	WP_011284591.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=249829 CRD75_RS02275 WP_002985680.1 417842..418843(+) (ccpA) [Streptococcus pyogenes strain HarveyGAS]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=249829 CRD75_RS02275 WP_002985680.1 417842..418843(+) (ccpA) [Streptococcus pyogenes strain HarveyGAS]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
TAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559