Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   APPSER1_RS05795 Genome accession   NZ_CP029003
Coordinates   1268966..1269631 (+) Length   221 a.a.
NCBI ID   WP_005619495.1    Uniprot ID   A0ABM6X4X3
Organism   Actinobacillus pleuropneumoniae serovar 1 str. 4074     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1263966..1274631
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  APPSER1_RS05770 (APPSER1_05770) - 1264908..1266241 (+) 1334 WP_108744155.1 IS3 family transposase -
  APPSER1_RS05775 (APPSER1_05775) - 1266390..1267283 (+) 894 WP_418910102.1 IS256 family transposase, variant Zn-binding type -
  APPSER1_RS05780 (APPSER1_05780) - 1267463..1267810 (+) 348 WP_005597890.1 YgiW/YdeI family stress tolerance OB fold protein -
  APPSER1_RS05785 (APPSER1_05785) - 1267866..1268462 (+) 597 WP_005597892.1 NirD/YgiW/YdeI family stress tolerance protein -
  APPSER1_RS05790 (APPSER1_05790) - 1268512..1268877 (+) 366 WP_117374030.1 YgiW/YdeI family stress tolerance OB fold protein -
  APPSER1_RS05795 (APPSER1_05795) ciaR 1268966..1269631 (+) 666 WP_005619495.1 response regulator Regulator
  APPSER1_RS05800 (APPSER1_05800) - 1269624..1271000 (+) 1377 WP_005597899.1 ATP-binding protein -
  APPSER1_RS05805 (APPSER1_05805) - 1271048..1271608 (-) 561 WP_005597901.1 YtfJ family protein -
  APPSER1_RS05810 (APPSER1_05810) yajC 1271802..1272098 (+) 297 WP_005597904.1 preprotein translocase subunit YajC -
  APPSER1_RS05815 (APPSER1_05815) secD 1272125..1273972 (+) 1848 WP_080550263.1 protein translocase subunit SecD -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25153.05 Da        Isoelectric Point: 5.7945

>NTDB_id=249557 APPSER1_RS05795 WP_005619495.1 1268966..1269631(+) (ciaR) [Actinobacillus pleuropneumoniae serovar 1 str. 4074]
MRILLIEDDKLIGDGLKLGLTKQNFVVDWFQDGKLGFEALFSTEYDAVVLDLTLPKMDGLAILKNWRKENLDIPVLILTA
RDTLDERILGFNSGADDYLCKPFALMEVVVRLQALIRRRYKQSSTEITLGDLTIDSSTHKVTLADKEINLTSKEFQLLLL
FASNKDRVLTRSAIEEKLYSWDNDVSSNAMEVYIHNLRKKLGKEWIKTVHGIGYKIGNSDA

Nucleotide


Download         Length: 666 bp        

>NTDB_id=249557 APPSER1_RS05795 WP_005619495.1 1268966..1269631(+) (ciaR) [Actinobacillus pleuropneumoniae serovar 1 str. 4074]
ATGCGTATTCTACTGATTGAAGACGACAAACTAATCGGTGACGGCTTAAAGCTGGGACTAACCAAACAAAATTTTGTCGT
TGATTGGTTCCAAGACGGTAAATTAGGCTTTGAAGCGTTATTCTCTACCGAATATGATGCGGTCGTTTTGGATTTAACGT
TACCTAAAATGGACGGTTTAGCCATTCTGAAAAATTGGCGTAAAGAAAATCTGGATATTCCGGTTTTAATCTTAACCGCA
AGGGATACGTTAGACGAAAGAATATTGGGATTTAATTCCGGTGCGGACGATTATCTCTGTAAGCCGTTTGCATTAATGGA
AGTGGTCGTCCGTTTACAAGCTCTAATTCGCCGCCGTTATAAACAGAGTTCCACCGAAATTACTCTCGGTGATCTGACGA
TTGACAGCAGTACCCACAAAGTAACCCTTGCCGATAAAGAGATCAATTTAACCTCGAAAGAATTTCAATTGCTGTTACTG
TTTGCCAGTAATAAAGATCGTGTTTTGACGCGTTCCGCTATCGAAGAAAAATTATACAGTTGGGATAACGACGTCAGCAG
TAACGCTATGGAAGTTTATATCCATAATTTACGTAAAAAACTCGGTAAAGAATGGATCAAAACCGTACACGGCATAGGTT
ATAAAATAGGAAATTCAGATGCTTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-111)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

37.778

100

0.385
  ciaR Streptococcus pneumoniae D39

37.778

100

0.385
  ciaR Streptococcus pneumoniae R6

37.778

100

0.385
  ciaR Streptococcus pneumoniae TIGR4

37.778

100

0.385
  ciaR Streptococcus mutans UA159

37.9

99.095

0.376

Multiple sequence alignment