Detailed information NTG0249174

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: MKLM6_RS18625
• Genome accession: NZ_CP023669
• Coordinates: 4135061..4136401 (-)
• Length: 446 a.a.
• NCBI ID: WP_054763602.1
• Uniprot ID: A0A172UC47
• Organism: Methylomonas koyamae strain LM6
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 4130061..4141401

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MKLM6_RS18610 (MKLM6_3651)	-	4131521..4132372 (-)	852	WP_064025374.1	HDOD domain-containing protein	-
MKLM6_RS18615 (MKLM6_3652)	-	4132553..4134388 (+)	1836	WP_096876476.1	EAL domain-containing protein	-
MKLM6_RS18620 (MKLM6_3653)	-	4134540..4135016 (+)	477	WP_096876477.1	hypothetical protein	-
MKLM6_RS18625 (MKLM6_3654)	pilR	4135061..4136401 (-)	1341	WP_054763602.1	sigma-54-dependent transcriptional regulator	Regulator
MKLM6_RS18630 (MKLM6_3655)	-	4136398..4137939 (-)	1542	WP_096876478.1	sensor histidine kinase	-
MKLM6_RS18635 (MKLM6_3656)	sucC	4138119..4139288 (+)	1170	WP_096876479.1	ADP-forming succinate--CoA ligase subunit beta	-
MKLM6_RS18640 (MKLM6_3657)	sucD	4139288..4140160 (+)	873	WP_096876480.1	succinate--CoA ligase subunit alpha	-

Sequence

Protein

• Length: 446 a.a.
• Molecular weight: 49534.08 Da
• Isoelectric Point: 6.2593

>NTDB_id=249174 MKLM6_RS18625 WP_054763602.1 4135061..4136401(-) (pilR) [Methylomonas koyamae strain LM6]
MNMPVTLVVDDEPDIRELLEITLNRMQIQTRSAATLAEAKHCLANQSFDLCLTDMRLPDGDGLELVDYIQAQGLTLPVAV
ITAHGSMDIAIKAMKKGAFDFLSKPVDLAVLRQLVSHALQISLNRVAEKERRTRDLLLGESAPMRNIRSKIDKVARNQAP
VYISGESGSGKELVARLIHQQSPRSEKAFIAINCGAIPHELMESEFFGHKKGSFTGAVSDKQGLFQAADGGTLFLDEVAD
LPLALQVKLLRAIQEKKIRPIGEQREIPVDVRLLSATHRDLAKMVQEGSFRQDLYYRINVIELNLPPLRARAADIPQLTE
HLLQGLARANGIAIPRLSDAALNALKQYYFPGNVRELENILERALALHEGGVIEVDDLNLPTGLDLAAAEDFDAEKMSLE
SYLEDIEKKALSSALEENRWNKTATAKYLGMSFRSLRYRLKKLGLE

Nucleotide

• Length: 1341 bp

>NTDB_id=249174 MKLM6_RS18625 WP_054763602.1 4135061..4136401(-) (pilR) [Methylomonas koyamae strain LM6]
ATGAATATGCCTGTTACGTTAGTGGTCGACGACGAGCCCGATATTCGGGAACTGTTGGAAATCACGTTAAACCGGATGCA
GATCCAGACCCGTAGCGCGGCTACGCTCGCCGAAGCCAAGCATTGTCTGGCTAATCAATCCTTCGATTTATGTTTGACCG
ACATGCGCTTGCCGGACGGAGACGGCTTGGAACTGGTCGATTACATCCAGGCCCAAGGTTTGACACTGCCGGTGGCGGTG
ATCACCGCCCACGGCAGCATGGATATCGCGATCAAGGCCATGAAAAAAGGCGCTTTCGATTTTCTGTCCAAGCCGGTCGA
TCTGGCGGTGTTAAGGCAATTGGTCAGCCATGCCTTGCAGATCTCGCTGAACCGGGTGGCCGAAAAGGAACGCCGCACCC
GCGATTTGTTGCTCGGGGAATCGGCGCCGATGCGCAATATCCGCTCCAAGATCGATAAAGTGGCGCGCAACCAGGCGCCG
GTTTACATCAGTGGCGAGTCGGGTTCCGGCAAGGAATTGGTGGCGCGGCTGATTCACCAGCAAAGCCCGCGCAGCGAAAA
GGCTTTTATCGCCATCAATTGCGGCGCGATTCCGCACGAATTGATGGAAAGCGAATTTTTCGGCCACAAAAAAGGCAGCT
TCACCGGGGCGGTCAGCGATAAGCAAGGTTTGTTTCAAGCCGCGGACGGCGGCACGCTGTTTCTGGACGAAGTGGCCGAT
TTGCCGTTGGCTTTGCAAGTCAAATTGCTGCGGGCGATACAGGAAAAGAAAATCCGCCCGATCGGCGAGCAGCGCGAAAT
TCCGGTGGACGTGCGTTTGCTGAGCGCAACCCACAGGGATTTGGCCAAAATGGTTCAGGAAGGCAGTTTTCGGCAGGACT
TGTATTACCGGATCAACGTCATCGAACTGAATCTGCCGCCATTACGGGCGCGAGCCGCCGATATTCCGCAATTGACCGAA
CATCTGCTGCAAGGTTTGGCGCGGGCCAACGGCATTGCTATCCCGCGCCTGTCGGATGCGGCGTTGAATGCGCTGAAACA
GTATTATTTTCCGGGCAACGTCCGCGAGTTGGAAAATATTTTGGAGCGGGCTTTGGCGCTGCACGAGGGCGGCGTGATCG
AGGTCGACGATTTGAATTTGCCGACCGGTTTGGACTTGGCCGCGGCGGAAGATTTCGATGCCGAAAAAATGTCGCTGGAA
AGTTATCTGGAAGATATCGAGAAAAAAGCGCTGAGTTCGGCTTTGGAGGAAAACCGCTGGAATAAAACCGCGACGGCTAA
ATATTTGGGTATGAGTTTCCGCTCGTTGCGTTACCGGTTGAAGAAACTCGGTCTGGAATAA

Domains

Predicted by InterproScan.

• Bacterial regulatory protein, Fis family (HTH_8) (403-443)

• Sigma-54 interaction domain (Sigma54_activat) (138-303)

• Response regulator receiver domain (Response_reg) (7-115)

3D structure

• AlphaFold DB: A0A172UC47

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	63.333	100	0.639
pilR	Acinetobacter baumannii strain A118	50.644	100	0.529
luxO	Vibrio cholerae strain A1552	39.189	99.552	0.39