Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   AOY56_RS02085 Genome accession   NZ_CP028769
Coordinates   454619..455251 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain A5     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 449619..460251
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AOY56_RS02060 (AOY56_02195) yhfG 449751..449918 (+) 168 WP_000736860.1 YhfG family protein -
  AOY56_RS02065 (AOY56_02200) fic 449908..450510 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  AOY56_RS02070 (AOY56_02205) pabA 450542..451105 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  AOY56_RS02075 (AOY56_02210) argD 451191..452411 (+) 1221 WP_000963785.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  AOY56_RS02080 (AOY56_02215) yhfK 452478..454568 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  AOY56_RS02085 (AOY56_02220) crp 454619..455251 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  AOY56_RS02090 (AOY56_02230) yhfA 455553..455957 (+) 405 WP_001148908.1 OsmC family protein -
  AOY56_RS02095 (AOY56_02235) prkB 456012..456881 (-) 870 WP_001274680.1 phosphoribulokinase -
  AOY56_RS02100 (AOY56_02240) yheU 456935..457153 (-) 219 WP_000907085.1 YheU family protein -
  AOY56_RS02105 (AOY56_02245) yheT 457147..458169 (-) 1023 WP_000057405.1 hydrolase -
  AOY56_RS02110 (AOY56_02250) yheS 458169..460082 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=248042 AOY56_RS02085 WP_000242755.1 454619..455251(-) (crp) [Escherichia coli strain A5]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=248042 AOY56_RS02085 WP_000242755.1 454619..455251(-) (crp) [Escherichia coli strain A5]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467