Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   CO686_RS08985 Genome accession   NZ_CP023507
Coordinates   1833395..1834693 (-) Length   432 a.a.
NCBI ID   WP_002880469.1    Uniprot ID   A0AAW7W617
Organism   Streptococcus oralis strain FDAARGOS_367     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1828395..1839693
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO686_RS08960 (CO686_08960) - 1828529..1829707 (-) 1179 WP_000656060.1 acetyl-CoA C-acetyltransferase -
  CO686_RS08965 (CO686_08965) - 1829726..1830574 (-) 849 WP_049501305.1 3-hydroxybutyryl-CoA dehydrogenase -
  CO686_RS08970 (CO686_08970) - 1830655..1831863 (-) 1209 WP_000201480.1 acyl-CoA dehydrogenase family protein -
  CO686_RS08975 (CO686_08975) raiA 1832108..1832656 (-) 549 WP_000599114.1 ribosome-associated translation inhibitor RaiA -
  CO686_RS08980 (CO686_08980) comFC/cflB 1832736..1833398 (-) 663 WP_000995722.1 ComF family protein Machinery gene
  CO686_RS08985 (CO686_08985) comFA/cflA 1833395..1834693 (-) 1299 WP_002880469.1 DEAD/DEAH box helicase Machinery gene
  CO686_RS08990 (CO686_08990) - 1834750..1835385 (+) 636 WP_000395750.1 YigZ family protein -
  CO686_RS08995 (CO686_08995) - 1835401..1835844 (+) 444 WP_000863902.1 PH domain-containing protein -
  CO686_RS09000 (CO686_09000) cysK 1835941..1836867 (+) 927 WP_000158482.1 cysteine synthase A -
  CO686_RS09005 (CO686_09005) tsf 1836971..1838011 (-) 1041 WP_000808059.1 translation elongation factor Ts -
  CO686_RS09010 (CO686_09010) rpsB 1838090..1838869 (-) 780 WP_000268475.1 30S ribosomal protein S2 -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49703.59 Da        Isoelectric Point: 8.2024

>NTDB_id=247888 CO686_RS08985 WP_002880469.1 1833395..1834693(-) (comFA/cflA) [Streptococcus oralis strain FDAARGOS_367]
MKVNPNYLGRLFTEKELTEEERQEAVRLPAMRKEKGKLFCQRCNSLILEEWYLPISAYYCRECLLMKRIRSDKALYYFPQ
EDFPKQDVLKWRGQLTPFQEKVSEGLLQAVDKQEPTLVHAVTGAGKTEMIYQVVAKVIDDGGAVCLASPRIDVCLELYKR
LQNDFACDIALLHGESEPYFRTPLVVATTHQLLKFYHAFDLLIVDEVDAFPYVDNTMLYYAVKNSVKEDGLRIFLTATST
DELDRKVRTGELKRLSLPRRFHGNPLIIPKPVWLSDFNRCLEKNQLSTKLKTYIEKQRRTGYPLLIFASEIKKGEKLKEI
LKEQYPNENIGFVSSVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGGRVGRSMDR
PTGELLFFHDGLNASIKKAIKEIKNMNKEAGL

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=247888 CO686_RS08985 WP_002880469.1 1833395..1834693(-) (comFA/cflA) [Streptococcus oralis strain FDAARGOS_367]
ATGAAAGTAAATCCAAATTATCTCGGTCGCTTGTTTACTGAGAAAGAATTAACGGAAGAAGAACGACAGGAAGCAGTGAG
ACTGCCAGCAATGAGAAAAGAGAAGGGGAAACTGTTTTGTCAACGTTGTAATAGTTTGATTCTAGAAGAATGGTATTTGC
CTATCAGCGCTTACTATTGTAGGGAGTGTTTACTGATGAAGAGAATCAGGAGTGATAAAGCTTTATACTATTTTCCTCAA
GAGGATTTTCCTAAGCAAGACGTCCTCAAATGGCGTGGTCAGTTAACACCTTTTCAAGAAAAAGTGTCAGAGGGACTGCT
TCAGGCGGTAGACAAGCAAGAGCCAACCTTGGTTCACGCTGTGACAGGAGCTGGAAAGACAGAGATGATTTATCAAGTTG
TGGCTAAAGTGATTGATGATGGTGGTGCAGTTTGTTTGGCCAGTCCTCGAATTGATGTGTGTTTAGAACTGTATAAGCGA
CTGCAGAATGACTTTGCTTGCGATATAGCGCTACTCCATGGCGAATCAGAGCCCTATTTTCGAACTCCCTTAGTAGTTGC
AACAACTCATCAGTTATTAAAATTTTATCATGCTTTTGATTTGTTGATAGTGGATGAGGTAGATGCCTTTCCTTATGTTG
ACAACACTATGCTTTACTATGCTGTAAAGAATAGTGTAAAGGAGGATGGATTGAGGATATTCCTTACGGCAACTTCTACA
GATGAGTTAGATAGGAAGGTTCGCACAGGGGAATTAAAAAGATTAAGCTTGCCGAGACGGTTTCATGGAAATCCTTTGAT
TATTCCTAAACCAGTCTGGTTATCGGATTTTAATCGCTGTTTAGAGAAAAATCAATTGTCAACCAAGTTAAAGACTTATA
TTGAGAAACAGAGAAGAACAGGTTATCCCTTACTGATTTTTGCATCAGAGATTAAGAAAGGTGAAAAACTAAAAGAAATC
TTGAAGGAGCAGTACCCGAATGAGAATATCGGCTTTGTGTCTTCTGTGACAGAAGACCGATTAGAGCAGGTGCAAGCTTT
TCGAGATGGAGAACTAACAATACTGATCAGTACGACAATCTTGGAACGCGGGGTTACCTTCCCTTGTGTGGATGTTTTCG
TAGTAGAAGCTAATCATCGTCTCTTTACCAAGTCTAGTTTGATTCAGATTGGAGGGCGAGTTGGACGCAGTATGGACAGA
CCAACTGGTGAGTTGCTCTTCTTTCATGATGGATTAAATGCTTCCATCAAAAAGGCAATCAAGGAAATCAAGAATATGAA
TAAGGAGGCAGGGTTATGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(292-396)

Type III restriction enzyme, res subunit (ResIII)

(94-167)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

90.741

100

0.907
  comFA/cflA Streptococcus pneumoniae Rx1

90.509

100

0.905
  comFA/cflA Streptococcus pneumoniae D39

90.509

100

0.905
  comFA/cflA Streptococcus pneumoniae R6

90.509

100

0.905
  comFA/cflA Streptococcus pneumoniae TIGR4

90.278

100

0.903
  comFA/cflA Streptococcus mitis SK321

89.583

100

0.896
  comFA Lactococcus lactis subsp. cremoris KW2

50.611

94.676

0.479
  comFA Latilactobacillus sakei subsp. sakei 23K

38.851

100

0.391

Multiple sequence alignment