Detailed information NTG0247835

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: CO686_RS00335
• Genome accession: NZ_CP023507
• Coordinates: 58278..59288 (+)
• Length: 336 a.a.
• NCBI ID: WP_001090635.1
• Uniprot ID: I0Q241
• Organism: Streptococcus oralis strain FDAARGOS_367
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 53278..64288

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CO686_RS00310 (CO686_00310)	-	53510..54832 (+)	1323	WP_065371417.1	folylpolyglutamate synthase/dihydrofolate synthase family protein	-
CO686_RS00315 (CO686_00315)	folE	54813..55367 (+)	555	WP_000380933.1	GTP cyclohydrolase I FolE	-
CO686_RS00320 (CO686_00320)	folK	55608..56429 (+)	822	WP_049500585.1	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	-
CO686_RS00325 (CO686_00325)	-	56422..57705 (+)	1284	WP_049500583.1	hypothetical protein	-
CO686_RS00330 (CO686_00330)	-	57756..58073 (-)	318	WP_000886047.1	DUF960 domain-containing protein	-
CO686_RS00335 (CO686_00335)	ccpA	58278..59288 (+)	1011	WP_001090635.1	catabolite control protein A	Regulator
CO686_RS00340 (CO686_00340)	-	59341..60303 (-)	963	WP_049500580.1	asparaginase	-
CO686_RS00345 (CO686_00345)	-	60369..61760 (+)	1392	WP_000453123.1	Cof-type HAD-IIB family hydrolase	-
CO686_RS00350 (CO686_00350)	-	62267..64276 (+)	2010	WP_000731511.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37214.23 Da
• Isoelectric Point: 5.5033

>NTDB_id=247835 CO686_RS00335 WP_001090635.1 58278..59288(+) (ccpA) [Streptococcus oralis strain FDAARGOS_367]
MNTDDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
TLAKGIDDIAEMYKYNIVLANSDEDDEKEVSVVNTLFSKQVDGIIFMGYHLTEKIRSEFSRSRTPVVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLLKENEKIAFVSGPLVDDINGKVRLIGYKEALKKAGHSYSEGLVFESKYSYDDGYALAERLISSQ
ATAAVVTGDELAAGVLNGLADHGVSVPEEFEIITTDDSQIARFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERRSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=247835 CO686_RS00335 WP_001090635.1 58278..59288(+) (ccpA) [Streptococcus oralis strain FDAARGOS_367]
ATGAACACAGATGATACAGTAACGATTTATGACGTCGCCCGTGAAGCAGGAGTTTCGATGGCAACAGTTAGCCGTGTCGT
TAATGGCAACAAGAATGTTAAAGAGAACACTCGAAAAAAAGTCCTAGAAGTGATTGATCGCTTGGACTATCGTCCAAATG
CGGTAGCACGTGGTTTGGCTAGCAAGAAAACAACGACAGTCGGAGTTGTGATTCCTAACATTACCAATGGTTATTTCTCA
ACGCTTGCTAAGGGAATTGACGACATTGCTGAAATGTACAAGTATAACATTGTCCTTGCAAATAGTGATGAGGATGATGA
AAAGGAAGTTTCAGTAGTCAACACTCTCTTTTCAAAACAAGTCGATGGGATTATCTTTATGGGCTATCACTTGACTGAAA
AGATTCGTTCAGAGTTTTCTCGTTCACGGACACCGGTTGTTCTTGCTGGTACTGTGGATGTAGAACACCAACTTCCAAGT
GTAAATATCGACTACAAACAAGCAACGATTGATGCTGTAAGCTACCTTCTAAAAGAAAACGAAAAGATTGCTTTTGTGAG
TGGACCACTCGTCGATGATATCAATGGCAAGGTTCGTTTGATTGGTTACAAGGAAGCCTTGAAAAAAGCAGGACATTCTT
ATAGCGAGGGATTGGTCTTTGAATCAAAATACAGCTATGACGATGGTTATGCCTTGGCAGAACGCTTGATTTCATCACAA
GCTACAGCCGCAGTTGTAACAGGTGATGAATTGGCAGCAGGTGTGTTGAATGGTTTGGCTGACCATGGCGTATCTGTGCC
GGAAGAGTTTGAAATCATTACGACAGATGACTCTCAGATTGCACGATTCACTCGTCCAAACTTGACGACTATTGCCCAAC
CTCTTTATGACCTAGGTGCTATCAGCATGCGTATGTTGACTAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCCTACCTCATGGTTTGACAGAACGCCGCTCTACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

3D structure

• AlphaFold DB: I0Q241

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	94.345	100	0.943
ccpA	Streptococcus gordonii str. Challis substr. CH1	88.623	99.405	0.881
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568