Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   AOY63_RS03845 Genome accession   NZ_CP028764
Coordinates   801779..802438 (-) Length   219 a.a.
NCBI ID   WP_001221493.1    Uniprot ID   Q3YXL4
Organism   Escherichia coli strain A10     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 796779..807438
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AOY63_RS03820 (AOY63_04130) - 797521..798468 (+) 948 WP_001305988.1 iron-siderophore ABC transporter substrate-binding protein -
  AOY63_RS03825 (AOY63_04135) - 798465..799352 (+) 888 WP_000614957.1 MurR/RpiR family transcriptional regulator -
  AOY63_RS03830 (AOY63_04140) ygiN 799397..799711 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  AOY63_RS03835 (AOY63_04145) mdaB 799742..800323 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  AOY63_RS03840 (AOY63_04150) qseC 800433..801782 (-) 1350 WP_000673373.1 quorum sensing histidine kinase QseC -
  AOY63_RS03845 (AOY63_04155) ciaR 801779..802438 (-) 660 WP_001221493.1 quorum sensing response regulator transcription factor QseB Regulator
  AOY63_RS03850 (AOY63_04160) ygiW 802590..802982 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  AOY63_RS03855 (AOY63_04165) ygiV 803035..803517 (+) 483 WP_000183504.1 GyrI-like domain-containing protein -
  AOY63_RS03860 (AOY63_04175) parC 804063..806321 (+) 2259 WP_001281919.1 DNA topoisomerase IV subunit A -
  AOY63_RS03865 (AOY63_04180) plsC 806555..807292 (+) 738 WP_000965712.1 1-acylglycerol-3-phosphate O-acyltransferase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24687.63 Da        Isoelectric Point: 6.9850

>NTDB_id=247809 AOY63_RS03845 WP_001221493.1 801779..802438(-) (ciaR) [Escherichia coli strain A10]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=247809 AOY63_RS03845 WP_001221493.1 801779..802438(-) (ciaR) [Escherichia coli strain A10]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTATATAGTGCGCCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGTTAGCGGAACGTGTAGAGGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAACTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACTCTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGCAGTGATTTTATTCGTACCGTTCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3YXL4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365