Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   AOY64_RS02060 Genome accession   NZ_CP028763
Coordinates   452306..452938 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain A11     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 447306..457938
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AOY64_RS02035 (AOY64_02160) yhfG 447438..447605 (+) 168 WP_000736860.1 YhfG family protein -
  AOY64_RS02040 (AOY64_02165) fic 447595..448197 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  AOY64_RS02045 (AOY64_02170) pabA 448229..448792 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  AOY64_RS02050 (AOY64_02175) argD 448878..450098 (+) 1221 WP_000963785.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  AOY64_RS02055 (AOY64_02180) yhfK 450165..452255 (-) 2091 WP_133296499.1 YccS/YhfK family putative transporter -
  AOY64_RS02060 (AOY64_02185) crp 452306..452938 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  AOY64_RS02065 (AOY64_02195) yhfA 453240..453644 (+) 405 WP_001148908.1 OsmC family protein -
  AOY64_RS02070 (AOY64_02200) prkB 453699..454568 (-) 870 WP_001274684.1 phosphoribulokinase -
  AOY64_RS02075 (AOY64_02205) yheU 454622..454840 (-) 219 WP_000907085.1 YheU family protein -
  AOY64_RS02080 (AOY64_02210) yheT 454834..455856 (-) 1023 WP_000057405.1 hydrolase -
  AOY64_RS02085 (AOY64_02215) yheS 455856..457769 (-) 1914 WP_024236179.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=247727 AOY64_RS02060 WP_000242755.1 452306..452938(-) (crp) [Escherichia coli strain A11]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=247727 AOY64_RS02060 WP_000242755.1 452306..452938(-) (crp) [Escherichia coli strain A11]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467