Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   AOY68_RS21075 Genome accession   NZ_CP028759
Coordinates   4376652..4377284 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain A15     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4371652..4382284
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AOY68_RS21050 (AOY68_22415) yheS 4371821..4373734 (+) 1914 WP_000634793.1 ABC transporter ATP-binding protein -
  AOY68_RS21055 (AOY68_22420) yheT 4373734..4374756 (+) 1023 WP_000057356.1 hydrolase -
  AOY68_RS21060 (AOY68_22425) yheU 4374750..4374968 (+) 219 WP_000907085.1 YheU family protein -
  AOY68_RS21065 (AOY68_22430) prkB 4375022..4375891 (+) 870 WP_001274680.1 phosphoribulokinase -
  AOY68_RS21070 (AOY68_22435) yhfA 4375946..4376350 (-) 405 WP_001148908.1 OsmC family protein -
  AOY68_RS21075 (AOY68_22445) crp 4376652..4377284 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  AOY68_RS21080 (AOY68_22450) yhfK 4377335..4379425 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  AOY68_RS21085 (AOY68_22455) argD 4379492..4380712 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  AOY68_RS21090 (AOY68_22460) pabA 4380798..4381361 (-) 564 WP_000601844.1 aminodeoxychorismate synthase component 2 -
  AOY68_RS21095 (AOY68_22465) fic 4381393..4381995 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  AOY68_RS21100 (AOY68_22470) yhfG 4381985..4382152 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=247463 AOY68_RS21075 WP_000242755.1 4376652..4377284(+) (crp) [Escherichia coli strain A15]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=247463 AOY68_RS21075 WP_000242755.1 4376652..4377284(+) (crp) [Escherichia coli strain A15]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467