Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   AOY69_RS20945 Genome accession   NZ_CP028758
Coordinates   4399654..4400286 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain A16     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4394654..4405286
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AOY69_RS20920 (AOY69_22185) yheS 4394823..4396736 (+) 1914 WP_119458048.1 ABC transporter ATP-binding protein -
  AOY69_RS20925 (AOY69_22190) yheT 4396736..4397758 (+) 1023 WP_201479729.1 hydrolase -
  AOY69_RS20930 (AOY69_22195) yheU 4397752..4397970 (+) 219 WP_000907085.1 YheU family protein -
  AOY69_RS20935 (AOY69_22200) prkB 4398024..4398893 (+) 870 WP_001274680.1 phosphoribulokinase -
  AOY69_RS20940 (AOY69_22205) yhfA 4398948..4399352 (-) 405 WP_001148908.1 OsmC family protein -
  AOY69_RS20945 (AOY69_22215) crp 4399654..4400286 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  AOY69_RS20950 (AOY69_22220) yhfK 4400337..4402427 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  AOY69_RS20955 (AOY69_22225) argD 4402494..4403714 (-) 1221 WP_119458047.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  AOY69_RS20960 (AOY69_22230) pabA 4403800..4404363 (-) 564 WP_000601857.1 aminodeoxychorismate synthase component 2 -
  AOY69_RS20965 (AOY69_22235) fic 4404395..4404997 (-) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  AOY69_RS20970 (AOY69_22240) yhfG 4404987..4405154 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=247386 AOY69_RS20945 WP_000242755.1 4399654..4400286(+) (crp) [Escherichia coli strain A16]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=247386 AOY69_RS20945 WP_000242755.1 4399654..4400286(+) (crp) [Escherichia coli strain A16]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467