Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   AOY69_RS13490 Genome accession   NZ_CP028758
Coordinates   2864045..2864701 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain A16     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2859045..2869701
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AOY69_RS13460 (AOY69_14290) yecA 2860296..2860961 (-) 666 WP_000847882.1 UPF0149 family protein YecA -
  AOY69_RS13480 (AOY69_14310) pgsA 2861611..2862159 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  AOY69_RS13485 (AOY69_14315) uvrC 2862216..2864048 (-) 1833 WP_028132062.1 excinuclease ABC subunit UvrC Machinery gene
  AOY69_RS13490 (AOY69_14320) letA 2864045..2864701 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  AOY69_RS23350 - 2864843..2864914 (+) 72 Protein_2632 transcriptional regulator -
  AOY69_RS13495 yecU 2864997..2865173 (+) 177 WP_000590347.1 protein YecU -
  AOY69_RS13500 (AOY69_14325) yecF 2865160..2865384 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  AOY69_RS13505 (AOY69_14330) sdiA 2865452..2866174 (-) 723 WP_024231281.1 transcriptional regulator SdiA -
  AOY69_RS13510 (AOY69_14335) tcyN 2866404..2867156 (-) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  AOY69_RS13515 (AOY69_14340) tcyL 2867153..2867821 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  AOY69_RS13520 (AOY69_14345) dcyD 2867836..2868822 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=247359 AOY69_RS13490 WP_000611328.1 2864045..2864701(-) (letA) [Escherichia coli strain A16]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=247359 AOY69_RS13490 WP_000611328.1 2864045..2864701(-) (letA) [Escherichia coli strain A16]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482