Detailed information NTG0247066

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: CLI98_RS06815
• Genome accession: NZ_CP023431
• Coordinates: 1347918..1349081 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain SCGB 574
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1342918..1354081

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CLI98_RS06785 (CLI98_01336)	-	1343183..1343602 (-)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-
CLI98_RS06790 (CLI98_01337)	comFC	1343676..1344365 (-)	690	WP_197538213.1	ComF family protein	Machinery gene
CLI98_RS06795 (CLI98_01338)	-	1344371..1344655 (-)	285	WP_022553866.1	competence protein ComFB	-
CLI98_RS06800 (CLI98_01339)	comFA	1344713..1346098 (-)	1386	WP_022553867.1	DEAD/DEAH box helicase	Machinery gene
CLI98_RS06805 (CLI98_01340)	-	1346206..1347054 (-)	849	WP_003151387.1	DegV family protein	-
CLI98_RS06810 (CLI98_01341)	degU	1347152..1347841 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
CLI98_RS06815 (CLI98_01342)	degS	1347918..1349081 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
CLI98_RS06820 (CLI98_01343)	-	1349304..1349951 (+)	648	WP_007407485.1	YigZ family protein	-
CLI98_RS06825 (CLI98_01344)	-	1349956..1351170 (+)	1215	WP_022553868.1	LCP family protein	-
CLI98_RS06830 (CLI98_01345)	-	1351270..1352346 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
CLI98_RS06835 (CLI98_01346)	-	1352478..1353674 (-)	1197	WP_022553869.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=247066 CLI98_RS06815 WP_007407484.1 1347918..1349081(-) (degS) [Bacillus velezensis strain SCGB 574]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=247066 CLI98_RS06815 WP_007407484.1 1347918..1349081(-) (degS) [Bacillus velezensis strain SCGB 574]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTTAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCTGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951