Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   AOY78_RS20235 Genome accession   NZ_CP028750
Coordinates   4129247..4129879 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain A25     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4124247..4134879
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AOY78_RS20205 (AOY78_21450) - 4124771..4125664 (+) 894 Protein_3945 hydrolase -
  AOY78_RS20210 (AOY78_21460) - 4125829..4127202 (+) 1374 WP_201479114.1 IS4-like element ISEc13 family transposase -
  AOY78_RS20215 (AOY78_21465) - 4127214..4127351 (+) 138 Protein_3947 hydrolase -
  AOY78_RS20220 (AOY78_21470) yheU 4127345..4127563 (+) 219 WP_000907085.1 YheU family protein -
  AOY78_RS20225 (AOY78_21475) prkB 4127617..4128486 (+) 870 WP_001274684.1 phosphoribulokinase -
  AOY78_RS20230 (AOY78_21480) yhfA 4128541..4128945 (-) 405 WP_001148908.1 OsmC family protein -
  AOY78_RS20235 (AOY78_21490) crp 4129247..4129879 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  AOY78_RS20240 (AOY78_21495) yhfK 4129930..4132020 (+) 2091 WP_001298205.1 YccS/YhfK family putative transporter -
  AOY78_RS20245 (AOY78_21500) argD 4132087..4133307 (-) 1221 WP_000963803.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  AOY78_RS20250 (AOY78_21505) pabA 4133393..4133956 (-) 564 WP_000601853.1 aminodeoxychorismate synthase component 2 -
  AOY78_RS20255 (AOY78_21510) fic 4133988..4134590 (-) 603 WP_001280662.1 putative adenosine monophosphate-protein transferase Fic -
  AOY78_RS20260 (AOY78_21515) yhfG 4134580..4134747 (-) 168 WP_000736859.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=246731 AOY78_RS20235 WP_000242755.1 4129247..4129879(+) (crp) [Escherichia coli strain A25]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=246731 AOY78_RS20235 WP_000242755.1 4129247..4129879(+) (crp) [Escherichia coli strain A25]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAAGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGCCGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment