Detailed information NTG0246006

Bioinformatically predicted

Overview

• Name: spo0A
• Type: Regulator
• Locus tag: CLI97_RS02710
• Genome accession: NZ_CP023320
• Coordinates: 500621..501421 (-)
• Length: 266 a.a.
• NCBI ID: WP_003153177.1
• Uniprot ID: I2C7K5
• Organism: Bacillus velezensis strain SCGB
• Function: activation and repression of comK; repression of rok; repression of abrB (predicted from homology) Competence regulation

Genomic Context

Location: 495621..506421

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CLI97_RS02665 (CLI97_00536)	-	495795..496166 (-)	372	WP_172424423.1	DUF2493 domain-containing protein	-
CLI97_RS02670 (CLI97_00537)	-	496163..496945 (-)	783	WP_094247745.1	DNA replication protein	-
CLI97_RS20925 (CLI97_00538)	-	496965..497117 (-)	153	WP_172424417.1	hypothetical protein	-
CLI97_RS02675 (CLI97_00539)	-	497114..497470 (-)	357	WP_094247744.1	hypothetical protein	-
CLI97_RS02680 (CLI97_00540)	-	497467..498087 (-)	621	WP_094247743.1	hypothetical protein	-
CLI97_RS20930 (CLI97_00541)	-	498108..498278 (-)	171	WP_153986733.1	hypothetical protein	-
CLI97_RS02685 (CLI97_00542)	-	498304..498681 (-)	378	WP_094247742.1	hypothetical protein	-
CLI97_RS02690 (CLI97_00543)	-	498678..499040 (-)	363	WP_094247741.1	hypothetical protein	-
CLI97_RS02695 (CLI97_00544)	-	499037..499219 (-)	183	WP_253252030.1	hypothetical protein	-
CLI97_RS02700 (CLI97_00545)	-	499255..499578 (-)	324	WP_094247740.1	hypothetical protein	-
CLI97_RS20935 (CLI97_00546)	-	499568..499732 (-)	165	WP_172424422.1	hypothetical protein	-
CLI97_RS02705 (CLI97_00547)	-	499928..500305 (-)	378	WP_094247739.1	helix-turn-helix domain-containing protein	-
CLI97_RS02710 (CLI97_00548)	spo0A	500621..501421 (-)	801	WP_003153177.1	sporulation transcription factor Spo0A	Regulator
CLI97_RS02715 (CLI97_00549)	spoIVB	501702..502982 (-)	1281	WP_007408360.1	SpoIVB peptidase	-
CLI97_RS02720 (CLI97_00550)	recN	503146..504876 (-)	1731	WP_094247738.1	DNA repair protein RecN	Machinery gene
CLI97_RS02725 (CLI97_00551)	ahrC	504908..505357 (-)	450	WP_003153173.1	transcriptional regulator AhrC/ArgR	-
CLI97_RS02730 (CLI97_00552)	-	505452..506297 (-)	846	WP_003153172.1	TlyA family RNA methyltransferase	-

Sequence

Protein

• Length: 266 a.a.
• Molecular weight: 29630.11 Da
• Isoelectric Point: 6.1630

>NTDB_id=246006 CLI97_RS02710 WP_003153177.1 500621..501421(-) (spo0A) [Bacillus velezensis strain SCGB]
MEKIKVCVADDNRELVSLLSEYIEGQDDMEVIGVAYNGQECLSLFKDKNPDVLVLDIIMPHLDGLAVLERLRESELEKQP
NVIMLTAFGQEDVTKKAVDLGASYFILKPFDMENLVGHIRQVSGNVSSVTHRAPSAQSSIIRSQPEPKRKNLDASITSII
HEIGVPAHIKGYLYLREAISMVYNDIELLGSITKVLYPDIAKKFNTTASRVERAIRHAIEVAWSRGNIDSISSLFGYTVS
MTKAKPTNSEFIAMVADKLRLEHKAS

Nucleotide

• Length: 801 bp

>NTDB_id=246006 CLI97_RS02710 WP_003153177.1 500621..501421(-) (spo0A) [Bacillus velezensis strain SCGB]
GTGGAGAAAATTAAAGTTTGTGTTGCTGATGATAATCGAGAGCTTGTAAGCCTGTTGAGTGAATATATAGAGGGACAGGA
TGATATGGAAGTGATCGGCGTTGCTTATAACGGACAGGAATGTCTTTCTTTGTTTAAAGATAAGAATCCCGATGTGCTCG
TGTTAGACATTATCATGCCGCATCTGGACGGACTTGCGGTTTTGGAGCGTCTGCGGGAATCAGAGCTCGAGAAGCAGCCG
AACGTCATCATGCTGACGGCATTCGGTCAGGAAGACGTTACGAAAAAAGCCGTCGATTTAGGCGCGTCCTATTTTATCCT
GAAGCCGTTTGATATGGAAAACCTTGTCGGCCATATCCGCCAGGTAAGCGGAAATGTCAGCAGTGTCACACACCGTGCGC
CGTCCGCGCAAAGCAGCATTATCCGCAGCCAGCCGGAGCCGAAACGGAAAAATCTCGATGCCAGCATTACAAGCATTATC
CATGAGATCGGTGTGCCTGCCCATATCAAAGGCTATCTTTATTTGCGTGAAGCCATTTCCATGGTGTATAACGATATTGA
ACTCCTCGGCAGCATCACAAAAGTCCTTTATCCCGACATTGCCAAAAAATTCAACACGACCGCAAGCCGTGTAGAACGGG
CCATCCGCCACGCCATTGAAGTCGCATGGAGCAGGGGAAATATTGATTCCATTTCTTCACTGTTCGGATATACCGTAAGC
ATGACAAAAGCAAAACCAACCAACTCAGAGTTCATCGCGATGGTTGCTGACAAGCTGAGATTGGAGCATAAAGCTTCGTA
A

Domains

Predicted by InterproScan.

• Sporulation initiation factor Spo0A C terminal (Spo0A_C) (156-259)

• Response regulator receiver domain (Response_reg) (6-119)

3D structure

• AlphaFold DB: I2C7K5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
spo0A	Bacillus subtilis subsp. subtilis str. 168	96.629	100	0.97