Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   AOY87_RS22485 Genome accession   NZ_CP028741
Coordinates   4544595..4545227 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain A34     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4539595..4550227
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AOY87_RS22460 (AOY87_23705) yheS 4539762..4541675 (+) 1914 WP_112844378.1 ABC transporter ATP-binding protein -
  AOY87_RS22465 (AOY87_23710) yheT 4541675..4542698 (+) 1024 Protein_4392 hydrolase -
  AOY87_RS22470 (AOY87_23715) yheU 4542692..4542911 (+) 220 Protein_4393 YheU family protein -
  AOY87_RS22475 (AOY87_23720) prkB 4542965..4543834 (+) 870 WP_001274684.1 phosphoribulokinase -
  AOY87_RS22480 (AOY87_23725) yhfA 4543889..4544293 (-) 405 WP_001148908.1 OsmC family protein -
  AOY87_RS22485 (AOY87_23735) crp 4544595..4545227 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  AOY87_RS22490 (AOY87_23740) yhfK 4545278..4547368 (+) 2091 WP_240765701.1 YccS/YhfK family putative transporter -
  AOY87_RS22495 (AOY87_23745) argD 4547435..4548655 (-) 1221 WP_240765702.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  AOY87_RS22500 (AOY87_23750) pabA 4548741..4549304 (-) 564 WP_000601850.1 aminodeoxychorismate synthase component 2 -
  AOY87_RS22505 (AOY87_23755) fic 4549336..4549938 (-) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  AOY87_RS22510 (AOY87_23760) yhfG 4549928..4550095 (-) 168 WP_032264260.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=246006 AOY87_RS22485 WP_000242755.1 4544595..4545227(+) (crp) [Escherichia coli strain A34]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=246006 AOY87_RS22485 WP_000242755.1 4544595..4545227(+) (crp) [Escherichia coli strain A34]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment