Detailed information NTG0024535

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: M5005_RS02245
• Genome accession: NC_007297
• Coordinates: 415424..416425 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes MGAS5005
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 410424..421425

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M5005_RS02220 (M5005_Spy0419)	-	411098..411781 (-)	684	WP_002990714.1	DUF969 domain-containing protein	-
M5005_RS02225 (M5005_Spy0420)	-	411992..412918 (-)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
M5005_RS02230 (M5005_Spy0421)	-	413063..413440 (-)	378	WP_002985686.1	VOC family protein	-
M5005_RS02235 (M5005_Spy0422)	-	413451..414116 (-)	666	WP_010921982.1	NAD(P)H-dependent oxidoreductase	-
M5005_RS02240 (M5005_Spy0423)	-	414165..415250 (-)	1086	WP_002985682.1	aminopeptidase P family protein	-
M5005_RS02245 (M5005_Spy0424)	ccpA	415424..416425 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
M5005_RS02250 (M5005_Spy0425)	-	416556..417554 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
M5005_RS02255 (M5005_Spy0426)	-	417556..418890 (+)	1335	WP_002994187.1	glycosyltransferase family 4 protein	-
M5005_RS02260 (M5005_Spy0427)	thrS	419312..421255 (+)	1944	WP_010921984.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=24535 M5005_RS02245 WP_002985680.1 415424..416425(+) (ccpA) [Streptococcus pyogenes MGAS5005]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=24535 M5005_RS02245 WP_002985680.1 415424..416425(+) (ccpA) [Streptococcus pyogenes MGAS5005]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGCCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCGGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559