Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccpA   Type   Regulator
Locus tag   M28_RS02280 Genome accession   NC_007296
Coordinates   418138..419139 (+) Length   333 a.a.
NCBI ID   WP_002985680.1    Uniprot ID   A0A4U7H1B9
Organism   Streptococcus pyogenes MGAS6180     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 413138..424139
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M28_RS02255 (M28_Spy0407) - 413812..414495 (-) 684 WP_011017476.1 DUF969 domain-containing protein -
  M28_RS02260 (M28_Spy0408) - 414706..415632 (-) 927 WP_011017477.1 glycosyltransferase family 2 protein -
  M28_RS02265 (M28_Spy0409) - 415777..416154 (-) 378 WP_002985686.1 VOC family protein -
  M28_RS02270 (M28_Spy0410) - 416165..416830 (-) 666 WP_002985684.1 NAD(P)H-dependent oxidoreductase -
  M28_RS02275 (M28_Spy0411) - 416879..417964 (-) 1086 WP_011284589.1 aminopeptidase P family protein -
  M28_RS02280 (M28_Spy0412) ccpA 418138..419139 (+) 1002 WP_002985680.1 catabolite control protein A Regulator
  M28_RS02285 (M28_Spy0413) - 419270..420268 (+) 999 WP_002990703.1 glycosyltransferase family 4 protein -
  M28_RS02290 (M28_Spy0414) - 420270..421604 (+) 1335 WP_011284590.1 glycosyltransferase family 4 protein -
  M28_RS02295 (M28_Spy0415) thrS 422026..423969 (+) 1944 WP_011284591.1 threonine--tRNA ligase -

Sequence

Protein


Download         Length: 333 a.a.        Molecular weight: 36713.83 Da        Isoelectric Point: 5.9985

>NTDB_id=24479 M28_RS02280 WP_002985680.1 418138..419139(+) (ccpA) [Streptococcus pyogenes MGAS6180]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide


Download         Length: 1002 bp        

>NTDB_id=24479 M28_RS02280 WP_002985680.1 418138..419139(+) (ccpA) [Streptococcus pyogenes MGAS6180]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
TAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

Periplasmic binding protein-like domain (Peripla_BP_3)

(177-332)

Bacterial regulatory proteins, lacI family (LacI)

(8-53)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4U7H1B9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccpA Streptococcus gordonii str. Challis substr. CH1

78.078

100

0.781
  ccpA Streptococcus pneumoniae D39

75.375

100

0.754
  ccpA Lactococcus lactis subsp. lactis strain DGCC12653

56.193

99.399

0.559

Multiple sequence alignment