Detailed information NTG0244226

Bioinformatically predicted

Overview

• Name: crp
• Type: Regulator
• Locus tag: Aba10042_RS12290
• Genome accession: NZ_CP023026
• Coordinates: 2532604..2533269 (+)
• Length: 221 a.a.
• NCBI ID: WP_000203219.1
• Uniprot ID: A0A219CAS9
• Organism: Acinetobacter baumannii strain 10042
• Function: regulate competence development (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	2530513..2534416	2532604..2533269	within	0

Gene organization within MGE regions

Location: 2530513..2534416

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Aba10042_RS12285 (Aba10042_12230)	-	2531743..2532165 (-)	423	WP_001195082.1	OsmC family protein	-
Aba10042_RS20490 (Aba10042_12235)	-	2532244..2532363 (-)	120	Protein_2379	hypothetical protein	-
Aba10042_RS12290 (Aba10042_12240)	crp	2532604..2533269 (+)	666	WP_000203219.1	cAMP-activated global transcriptional regulator CRP	Regulator
Aba10042_RS12295 (Aba10042_12245)	-	2533326..2534416 (+)	1091	WP_085940413.1	IS4-like element ISAba1 family transposase	-

Sequence

Protein

• Length: 221 a.a.
• Molecular weight: 24956.78 Da
• Isoelectric Point: 8.1128

>NTDB_id=244226 Aba10042_RS12290 WP_000203219.1 2532604..2533269(+) (crp) [Acinetobacter baumannii strain 10042]
MTSNFSQLSTDALSPGQLPESVKALLKRAHINRYPKRTTIVDAGTESKSLYLILKGSVSIILREDDEREIVVAYLNPGDF
FGEMGLFEPNPQRTAEVRTRDVCEIAEISYDNFHELSKQYPDLSYAVFAQLVRRLKNTTRKMTDLAFIDVSGRIARCLID
LSSQPEAMILPNGRQIRITRQEIGRIVGCSREMVGRVLKTLEDQGMIQTDGKAILIFLCTR

Nucleotide

• Length: 666 bp

>NTDB_id=244226 Aba10042_RS12290 WP_000203219.1 2532604..2533269(+) (crp) [Acinetobacter baumannii strain 10042]
ATGACTTCAAATTTTTCACAACTCAGCACAGATGCTTTATCTCCGGGGCAACTACCTGAATCCGTTAAAGCATTGTTAAA
ACGTGCTCACATCAACAGATATCCAAAACGAACCACAATTGTTGATGCCGGAACAGAGTCAAAATCTTTATATTTAATTT
TAAAAGGCTCAGTTTCAATTATTTTACGTGAAGACGATGAACGTGAAATTGTTGTGGCATATTTGAATCCTGGTGACTTC
TTTGGGGAAATGGGGCTTTTCGAACCGAACCCTCAACGTACAGCTGAAGTTCGTACCCGTGATGTCTGTGAAATTGCGGA
AATTTCATATGACAACTTCCACGAACTGAGCAAACAGTATCCAGATCTCAGCTATGCCGTTTTCGCGCAACTCGTTCGTC
GTTTAAAAAATACAACTCGTAAAATGACCGATCTTGCATTTATTGATGTGTCAGGCCGTATTGCGCGTTGCTTAATCGAC
CTATCTTCACAACCAGAAGCAATGATCTTGCCGAATGGCCGTCAAATTCGTATTACTCGACAAGAGATTGGACGCATTGT
CGGGTGTTCACGAGAAATGGTTGGCCGTGTATTAAAGACCTTAGAAGATCAAGGTATGATTCAAACTGACGGTAAAGCTA
TTCTAATTTTTCTCTGTACACGATAA

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, crp family (Crp) (176-207)

• Cyclic nucleotide-binding domain (cNMP_binding) (33-120)

3D structure

• AlphaFold DB: A0A219CAS9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
crp	Acinetobacter baumannii D1279779	100	98.19	0.982
crp	Vibrio cholerae strain A1552	47.317	92.76	0.439
crp	Haemophilus influenzae Rd KW20	48.705	87.33	0.425