Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   NTHI_RS05425 Genome accession   NC_007146
Coordinates   1074418..1075092 (+) Length   224 a.a.
NCBI ID   WP_005647998.1    Uniprot ID   Q4QLV0
Organism   Haemophilus influenzae 86-028NP     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1069418..1080092
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NTHI_RS05390 (NTHI1123) rpmG 1070335..1070505 (-) 171 WP_005613503.1 50S ribosomal protein L33 -
  NTHI_RS05395 (NTHI1124) rpmB 1070517..1070753 (-) 237 WP_005542826.1 50S ribosomal protein L28 -
  NTHI_RS05400 (NTHI1125) radC 1070967..1071632 (-) 666 WP_013526173.1 RadC family protein -
  NTHI_RS05405 (NTHI1126) coaBC 1071795..1072997 (+) 1203 WP_011272308.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  NTHI_RS05410 (NTHI1127) dut 1073045..1073500 (+) 456 WP_005631431.1 dUTP diphosphatase -
  NTHI_RS05415 (NTHI1128) slmA 1073504..1074160 (+) 657 WP_005648000.1 nucleoid occlusion factor SlmA -
  NTHI_RS05420 (NTHI1129) - 1074182..1074433 (+) 252 WP_005647999.1 YheU family protein -
  NTHI_RS05425 (NTHI1130) crp 1074418..1075092 (+) 675 WP_005647998.1 cAMP-activated global transcriptional regulator CRP Regulator
  NTHI_RS05430 (NTHI1131) rlmC 1075457..1076635 (-) 1179 WP_011272309.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  NTHI_RS05435 (NTHI1132) nagZ 1076628..1077683 (-) 1056 WP_011272310.1 beta-N-acetylhexosaminidase -
  NTHI_RS05440 (NTHI1133) - 1077687..1078037 (-) 351 WP_005686225.1 YcfL family protein -
  NTHI_RS05445 (NTHI1134) hinT 1078037..1078387 (-) 351 WP_041174747.1 purine nucleoside phosphoramidase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25151.85 Da        Isoelectric Point: 6.8375

>NTDB_id=24382 NTHI_RS05425 WP_005647998.1 1074418..1075092(+) (crp) [Haemophilus influenzae 86-028NP]
MSNELTEIDEVVTSSQEEATQRDPVLDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVTNLAFLDVAGRIAQ
TLMNLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=24382 NTHI_RS05425 WP_005647998.1 1074418..1075092(+) (crp) [Haemophilus influenzae 86-028NP]
ATGTCAAATGAATTAACCGAAATTGATGAAGTTGTAACCTCCTCTCAAGAAGAAGCAACTCAACGAGATCCCGTTTTAGA
TTGGTTTCTTACTCACTGCCATTTGCATAAGTATCCTGCAAAATCAACTTTAATTCATGCTGGGGAAGATGCGACCACGC
TGTATTATGTAATTAAAGGTTCTGTAATGGTATCTTCAAAAGATGATGAAGGCAAAGAGATGATCCTCACTTACTTAGGT
GCAGGACAATTTTTTGGCGAAGCGGGATTATTTGATGAAGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAAATTTCCTATAAGAAATATCGCCAGTTGATTCAGGCAAACCCTGAAATCTTAATGTTTCTTACTGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTCACGAATTTGGCATTTTTAGACGTCGCAGGTCGCATCGCTCAA
ACTTTAATGAACTTAGCTAAACAGCCTGAAGCAATGACGCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGTTGTTCACGAGAAACTGTGGGGCGCATTATTAAGATGTTGGAGGATCAGAATCTTATCCACGCTC
ATGGAAAAACAATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(36-124)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QLV0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

100

100

1
  crp Vibrio cholerae strain A1552

75.49

91.071

0.687
  crp Acinetobacter baumannii D1279779

48.705

86.161

0.42

Multiple sequence alignment