Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGF   Type   Machinery gene
Locus tag   CGP94_RS08040 Genome accession   NZ_CP022898
Coordinates   1607149..1607646 (-) Length   165 a.a.
NCBI ID   WP_001825340.1    Uniprot ID   A0A2S6DDC2
Organism   Staphylococcus aureus strain 422     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1602149..1612646
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CGP94_RS08015 (CGP94_01476) gcvPB 1602311..1603783 (-) 1473 WP_000202177.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPB -
  CGP94_RS08020 (CGP94_01477) gcvPA 1603776..1605122 (-) 1347 WP_000019687.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPA -
  CGP94_RS08025 (CGP94_01478) gcvT 1605142..1606233 (-) 1092 WP_000093354.1 glycine cleavage system aminomethyltransferase GcvT -
  CGP94_RS08030 (CGP94_01479) - 1606392..1606916 (-) 525 WP_001015120.1 shikimate kinase -
  CGP94_RS08035 - 1606906..1607052 (-) 147 WP_001789879.1 hypothetical protein -
  CGP94_RS08040 (CGP94_01480) comGF 1607149..1607646 (-) 498 WP_001825340.1 competence type IV pilus minor pilin ComGF Machinery gene
  CGP94_RS08045 (CGP94_01481) comGE 1607564..1607863 (-) 300 WP_000844415.1 hypothetical protein Machinery gene
  CGP94_RS08050 (CGP94_01482) comGD 1607850..1608296 (-) 447 WP_072357807.1 competence type IV pilus minor pilin ComGD Machinery gene
  CGP94_RS08055 (CGP94_01483) comGC 1608274..1608585 (-) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  CGP94_RS08060 (CGP94_01484) comGB 1608599..1609669 (-) 1071 WP_000776413.1 competence type IV pilus assembly protein ComGB Machinery gene
  CGP94_RS08065 (CGP94_01485) comGA 1609641..1610615 (-) 975 WP_000697222.1 competence type IV pilus ATPase ComGA Machinery gene
  CGP94_RS08070 (CGP94_01486) - 1610667..1611290 (-) 624 WP_047213494.1 MBL fold metallo-hydrolase -
  CGP94_RS08075 (CGP94_01487) - 1611287..1611616 (-) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  CGP94_RS08080 (CGP94_01488) - 1611616..1612602 (-) 987 WP_000161315.1 ROK family glucokinase -

Sequence

Protein


Download         Length: 165 a.a.        Molecular weight: 19179.92 Da        Isoelectric Point: 10.2192

>NTDB_id=242942 CGP94_RS08040 WP_001825340.1 1607149..1607646(-) (comGF) [Staphylococcus aureus strain 422]
MILSKVTNKFVLFQKIPLLIKRHVYSINVKAFSLIEMLVAMMVISITLLIVPDLIRLSKTFLIESRELTTVDFEFFSRDI
LEDFKGVDRNDIEIRQQRIILHKGEEMIEYKLINNKIIKVVNDRGNITLINNVTAFTANIYYKSIIKITITVKVGTNLQT
KTIYV

Nucleotide


Download         Length: 498 bp        

>NTDB_id=242942 CGP94_RS08040 WP_001825340.1 1607149..1607646(-) (comGF) [Staphylococcus aureus strain 422]
ATGATATTAAGCAAAGTGACCAACAAATTTGTGCTATTTCAAAAAATACCACTTCTTATCAAAAGACATGTATACAGTAT
TAATGTCAAAGCTTTTTCGCTTATTGAAATGTTAGTAGCGATGATGGTTATAAGTATAACTTTACTAATTGTTCCAGACT
TAATTAGACTTAGCAAAACTTTTCTAATTGAAAGTAGGGAATTAACAACTGTAGATTTCGAATTTTTCTCAAGAGATATT
CTAGAGGATTTTAAAGGAGTAGATAGAAACGATATTGAAATTAGGCAACAGCGTATCATTTTACATAAAGGTGAAGAAAT
GATCGAATACAAATTAATAAATAATAAAATTATTAAAGTTGTAAATGACAGAGGAAATATAACATTGATTAATAATGTTA
CAGCATTTACTGCAAATATCTACTATAAATCTATTATTAAAATAACGATAACAGTTAAAGTCGGTACAAATCTGCAGACT
AAAACTATTTATGTATAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(28-51)

Putative Competence protein ComGF (ComGF)

(68-155)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2S6DDC2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGF Staphylococcus aureus N315

98.182

100

0.982
  comGF Staphylococcus aureus MW2

96.97

100

0.97

Multiple sequence alignment