Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ssp1_RS04640 Genome accession   NZ_CP022881
Coordinates   955291..955920 (+) Length   209 a.a.
NCBI ID   WP_002452289.1    Uniprot ID   A0A2T4Q1G3
Organism   Staphylococcus sp. M0911     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 950291..960920
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ssp1_RS04610 (Ssp1_09350) - 950327..951052 (+) 726 WP_049423339.1 type 1 glutamine amidotransferase -
  ssp1_RS04615 (Ssp1_09360) - 951107..952096 (-) 990 WP_171970102.1 aromatic acid exporter family protein -
  ssp1_RS04620 (Ssp1_09370) map 952260..953015 (+) 756 WP_002452285.1 type I methionyl aminopeptidase -
  ssp1_RS04625 (Ssp1_09380) - 953159..953545 (+) 387 WP_118828139.1 DUF2543 family protein -
  ssp1_RS04630 (Ssp1_09390) liaF 953560..954261 (+) 702 WP_002452287.1 cell wall-active antibiotics response protein LiaF -
  ssp1_RS04635 (Ssp1_09400) vraS 954258..955301 (+) 1044 WP_002452288.1 sensor histidine kinase Regulator
  ssp1_RS04640 (Ssp1_09410) vraR 955291..955920 (+) 630 WP_002452289.1 two-component system response regulator VraR Regulator
  ssp1_RS04645 (Ssp1_09420) - 955978..957213 (-) 1236 WP_075777806.1 YihY/virulence factor BrkB family protein -
  ssp1_RS04650 (Ssp1_09430) - 957442..957726 (-) 285 WP_002466132.1 YtxH domain-containing protein -
  ssp1_RS04655 (Ssp1_09440) - 957733..958197 (-) 465 WP_049423330.1 low molecular weight protein-tyrosine-phosphatase -
  ssp1_RS04660 (Ssp1_09450) - 958344..958547 (+) 204 WP_002452293.1 DUF1128 domain-containing protein -
  ssp1_RS04665 (Ssp1_09460) - 958560..959801 (+) 1242 WP_075777807.1 aminopeptidase -
  ssp1_RS04670 (Ssp1_09470) - 959860..960390 (+) 531 WP_002452295.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23571.16 Da        Isoelectric Point: 4.8917

>NTDB_id=242467 ssp1_RS04640 WP_002452289.1 955291..955920(+) (vraR) [Staphylococcus sp. M0911]
MAIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGESGKDAIAKAHELQPDLILMDLLMDDMDGVEATTEIKKDLPHIKVV
MLTSFIEDKEVYRALDAGVDSYILKTTSASDIAEAVRKTYHGESVFEPEVLVKMRNRMKKRAELYEMLTDREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=242467 ssp1_RS04640 WP_002452289.1 955291..955920(+) (vraR) [Staphylococcus sp. M0911]
ATGGCGATTAAAGTATTATTTGTAGACGACCATGAGATGGTTAGAATAGGTATTTCAAGTTACTTATCAACACAATCTGA
CATTGAAGTAGTGGGAGAAGGTGAGTCTGGGAAAGATGCAATTGCAAAGGCACATGAGTTACAACCAGATTTGATTCTAA
TGGATTTACTTATGGATGATATGGATGGTGTAGAAGCGACAACAGAAATTAAAAAGGATTTACCACACATTAAAGTTGTG
ATGCTTACAAGTTTCATTGAAGATAAAGAAGTGTATCGAGCTCTAGATGCTGGTGTAGATAGTTATATCTTAAAGACCAC
AAGTGCTAGTGATATCGCAGAAGCGGTTCGTAAAACATATCATGGTGAATCGGTATTTGAACCAGAAGTATTAGTTAAAA
TGCGTAACAGAATGAAAAAACGTGCTGAGCTATACGAAATGTTAACAGATAGAGAAATGGAAATTTTATTGTTAATTGCT
AAAGGTTATTCTAATCAAGAGATTGCTAGTGCATCTCATATTACAATAAAAACAGTAAAAACTCATGTAAGTAATATTCT
AAGTAAATTAGAAGTTCAAGATAGAACACAGGCAGTCATTTATGCATTCCAACATAACTTAATTCAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2T4Q1G3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

93.78

100

0.938
  degU Bacillus subtilis subsp. subtilis str. 168

34.375

100

0.368

Multiple sequence alignment