Detailed information NTG0242466

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ssp1_RS04635
• Genome accession: NZ_CP022881
• Coordinates: 954258..955301 (+)
• Length: 347 a.a.
• NCBI ID: WP_002452288.1
• Uniprot ID: A0A2T4Q1J8
• Organism: Staphylococcus sp. M0911
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 949258..960301

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ssp1_RS04610 (Ssp1_09350)	-	950327..951052 (+)	726	WP_049423339.1	type 1 glutamine amidotransferase	-
ssp1_RS04615 (Ssp1_09360)	-	951107..952096 (-)	990	WP_171970102.1	aromatic acid exporter family protein	-
ssp1_RS04620 (Ssp1_09370)	map	952260..953015 (+)	756	WP_002452285.1	type I methionyl aminopeptidase	-
ssp1_RS04625 (Ssp1_09380)	-	953159..953545 (+)	387	WP_118828139.1	DUF2543 family protein	-
ssp1_RS04630 (Ssp1_09390)	liaF	953560..954261 (+)	702	WP_002452287.1	cell wall-active antibiotics response protein LiaF	-
ssp1_RS04635 (Ssp1_09400)	vraS	954258..955301 (+)	1044	WP_002452288.1	sensor histidine kinase	Regulator
ssp1_RS04640 (Ssp1_09410)	vraR	955291..955920 (+)	630	WP_002452289.1	two-component system response regulator VraR	Regulator
ssp1_RS04645 (Ssp1_09420)	-	955978..957213 (-)	1236	WP_075777806.1	YihY/virulence factor BrkB family protein	-
ssp1_RS04650 (Ssp1_09430)	-	957442..957726 (-)	285	WP_002466132.1	YtxH domain-containing protein	-
ssp1_RS04655 (Ssp1_09440)	-	957733..958197 (-)	465	WP_049423330.1	low molecular weight protein-tyrosine-phosphatase	-
ssp1_RS04660 (Ssp1_09450)	-	958344..958547 (+)	204	WP_002452293.1	DUF1128 domain-containing protein	-
ssp1_RS04665 (Ssp1_09460)	-	958560..959801 (+)	1242	WP_075777807.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40101.60 Da
• Isoelectric Point: 6.2449

>NTDB_id=242466 ssp1_RS04635 WP_002452288.1 954258..955301(+) (vraS) [Staphylococcus sp. M0911]
MNHYIRAIGSMLILIYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILLCIIVGSVLAYKINQQNDWIKT
QIERSIEGETVGINDQNIELYSETLEIYHTLVPLNQELHRLRMKTQNLTNENYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETQLEPPLDQQIPVLEKMIQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QEFKVPKGIEDHLFRITQEAISNTLRHSNGTRVTVELFNKQDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYGD

Nucleotide

• Length: 1044 bp

>NTDB_id=242466 ssp1_RS04635 WP_002452288.1 954258..955301(+) (vraS) [Staphylococcus sp. M0911]
ATGAATCACTATATAAGAGCCATTGGGTCAATGCTGATATTGATATATAGTATGTTAACGGCATTCTTATTTATTGATAA
AGTTTTTGTTAACATCATTTACTTTCAAGGCATGTTTTATACACAAATTTTCGGTATTCCAGTGTTCTTATTCTTAAATA
TTATAGTTATATTATTATGTATTATAGTCGGATCAGTTCTAGCATATAAAATTAATCAACAGAATGATTGGATTAAAACT
CAAATTGAGCGATCAATTGAAGGGGAAACAGTTGGTATTAATGACCAAAATATTGAATTGTATAGTGAGACTTTAGAAAT
ATATCATACACTCGTTCCATTAAATCAAGAGTTACATCGATTAAGAATGAAAACACAAAATTTAACTAACGAAAATTACA
ATATGAATGATGTTAAAGTTAAAAAAATTATTGAAGACGAGCGACAACGTTTAGCAAGAGAATTACACGATTCTGTAAGT
CAACAACTATTCGCTGCAAGTATGATGTTATCAGCAATTAAAGAAACACAGTTAGAACCACCATTAGATCAACAAATACC
TGTACTCGAAAAAATGATTCAAGATTCTCAACTTGAAATGAGAGCGTTGTTACTTCATTTAAGACCGCTAGGATTAAAAG
ATAAATCATTAGGTGAAGGAATTAAAGATTTAGTCATTGACCTTCAAAAGAAAGTTCCAATGAAAGTAGTACATGAGATT
CAAGAATTTAAAGTACCAAAAGGAATAGAGGATCATTTATTCAGAATTACACAAGAAGCAATTTCAAATACTTTGAGACA
TTCTAATGGTACAAGAGTAACGGTTGAATTATTTAATAAACAAGATTATTTATTGTTACGTATACAAGATAATGGTAAAG
GTTTTAATGTAGACGAGAAACTTGAGCAAAGTTATGGATTAAAGAATATGCGTGAACGTGCACTAGAAATTGGTGCTACT
TTCCATATCGTTTCATTACCAGATTCTGGTACACGTATTGAAGTTAAAGCACCATTAAACAAGGAGGATTCGTATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A2T4Q1J8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	94.524	100	0.945