Detailed information NTG0241633

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: CGP84_RS14060
• Genome accession: NZ_CP022682
• Coordinates: 2709961..2710848 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain 78
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2704961..2715848

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CGP84_RS14025	-	2704974..2705066 (+)	93	WP_010956583.1	hypothetical protein	-
CGP84_RS14030 (CGP84_02560)	-	2705174..2705671 (-)	498	WP_001065267.1	glutathione peroxidase	-
CGP84_RS14035	-	2705681..2705941 (-)	261	WP_115288446.1	hypothetical protein	-
CGP84_RS14045	-	2706323..2706436 (-)	114	WP_072357681.1	hypothetical protein	-
CGP84_RS14050 (CGP84_02561)	-	2707101..2709101 (-)	2001	WP_042907889.1	ABC transporter permease	-
CGP84_RS14055 (CGP84_02562)	-	2709098..2709853 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
CGP84_RS14060 (CGP84_02563)	braS	2709961..2710848 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
CGP84_RS14065 (CGP84_02564)	braR	2710859..2711524 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
CGP84_RS14070 (CGP84_02565)	-	2711550..2711750 (-)	201	WP_000604725.1	hypothetical protein	-
CGP84_RS14075 (CGP84_02566)	-	2711948..2713372 (+)	1425	WP_115288447.1	alkaline phosphatase	-
CGP84_RS14745	-	2713442..2713552 (+)	111	WP_001791296.1	hypothetical protein	-
CGP84_RS14085 (CGP84_02568)	-	2713655..2714110 (-)	456	WP_047213013.1	MarR family winged helix-turn-helix transcriptional regulator	-
CGP84_RS14090 (CGP84_02569)	-	2714355..2715116 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=241633 CGP84_RS14060 WP_000143420.1 2709961..2710848(-) (braS) [Staphylococcus aureus strain 78]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=241633 CGP84_RS14060 WP_000143420.1 2709961..2710848(-) (braS) [Staphylococcus aureus strain 78]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993