Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   CEP77_RS02390 Genome accession   NZ_CP028325
Coordinates   489262..491238 (-) Length   658 a.a.
NCBI ID   WP_108169954.1    Uniprot ID   -
Organism   Helicobacter pylori strain FDAARGOS_298     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 484262..496238
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CEP77_RS02365 (CEP77_02365) - 484339..484731 (+) 393 WP_000656174.1 4Fe-4S dicluster domain-containing protein -
  CEP77_RS02370 (CEP77_02370) - 484741..485964 (+) 1224 WP_108169164.1 2-oxoacid:ferredoxin oxidoreductase subunit alpha -
  CEP77_RS02375 (CEP77_02375) - 485977..486921 (+) 945 WP_000589024.1 thiamine pyrophosphate-dependent enzyme -
  CEP77_RS02380 (CEP77_02380) purB 487031..488353 (+) 1323 WP_108169165.1 adenylosuccinate lyase -
  CEP77_RS02385 (CEP77_02385) - 488418..489251 (+) 834 WP_108169166.1 outer membrane protein -
  CEP77_RS02390 (CEP77_02390) uvrB 489262..491238 (-) 1977 WP_108169954.1 excinuclease ABC subunit UvrB Machinery gene
  CEP77_RS02395 (CEP77_02395) - 491309..491923 (-) 615 WP_231952945.1 hypothetical protein -
  CEP77_RS08580 (CEP77_02400) - 491923..492117 (-) 195 WP_108169168.1 hypothetical protein -
  CEP77_RS02405 (CEP77_02405) - 492077..495439 (-) 3363 WP_231952823.1 DUF3519 domain-containing protein -

Sequence

Protein


Download         Length: 658 a.a.        Molecular weight: 75942.40 Da        Isoelectric Point: 6.8805

>NTDB_id=240689 CEP77_RS02390 WP_108169954.1 489262..491238(-) (uvrB) [Helicobacter pylori strain FDAARGOS_298]
MPLFDLKSPYPPAGDQPQAIEALTKSLKNNNHYQTLVGVTGSGKTYTMANIIAQTNKPALIMSHNKTLCAQLYSEFKAFF
PHNRVEYFISHFDYYQPESYIPRRDLFIEKDSSINDDLERLRLSATTSLLGYDDVIVIASVSANYGLGNPEEYLKVMEKI
KVGEKRAYKSFLLKLVEMGYSRNEVVFDRGSFRATGECVDIFPAYNDAEFIRIEFFGDEIERIAVFDALERNEIKRLDSV
MLYAASQFAVGSERLNLAIKSIEDELALRLKFFKEQDKMLEYNRLKQRTEHDLEMISTTGVCKGIENYARHFTGKAPNET
PFCLFDYLGIFEREFLVIVDESHVSLPQFGGMYAGDMSRKSVLVEYGFRLPSALDNRPLKFDEFIHKNCQFLFVSATPNK
LELELSKKNVAEQIIRPTGLLDPKFEVRDSDKQVQDLFDEIKLVVARDERVLITTLTKKMAEELCKYYAEWGLKARYMHS
EIDAIERNHIIRSLRLKEFDILIGINLLREGLDLPEVSLVAIMDADKEGFLRSETSLIQAMGRAARNANGKVLLYAKKTT
QSMQKAFEITSYRRAKQEEFNKIHNITPKTVTRALEEELKLRDDEIRIAKALKKDKIPKSEREKIIKELDKKMRECAKNL
DFEEAMRLRDEIAKLRTL

Nucleotide


Download         Length: 1977 bp        

>NTDB_id=240689 CEP77_RS02390 WP_108169954.1 489262..491238(-) (uvrB) [Helicobacter pylori strain FDAARGOS_298]
ATGCCTTTATTTGATTTAAAAAGCCCCTATCCACCAGCAGGCGATCAGCCCCAAGCCATAGAAGCCTTAACGAAAAGCTT
GAAAAATAACAACCATTATCAAACTTTAGTGGGGGTTACAGGGAGCGGTAAGACTTATACGATGGCCAATATCATCGCTC
AAACCAATAAACCCGCTTTGATCATGAGCCATAATAAGACCTTATGTGCACAGCTTTATAGCGAGTTTAAGGCGTTTTTC
CCGCATAATAGGGTGGAGTATTTTATCTCCCACTTTGATTACTACCAGCCTGAAAGCTATATCCCTAGGAGGGATTTATT
CATTGAAAAAGACAGCTCTATTAACGATGATTTAGAGCGTTTAAGATTGAGTGCGACCACCTCGCTTTTAGGTTATGATG
ATGTGATCGTGATAGCGAGCGTTTCGGCTAATTATGGTTTGGGTAACCCCGAAGAATATCTAAAAGTCATGGAAAAAATC
AAAGTGGGCGAGAAGCGTGCTTATAAGAGCTTTTTACTCAAACTAGTAGAAATGGGTTATAGCCGTAATGAAGTGGTGTT
TGATAGGGGGAGCTTTAGAGCGACGGGGGAATGCGTGGATATTTTCCCCGCTTATAATGACGCTGAATTTATTAGGATTG
AATTTTTTGGCGATGAGATAGAAAGGATTGCGGTCTTTGACGCTTTAGAAAGAAATGAAATCAAGCGCTTGGATTCTGTC
ATGCTTTATGCGGCCAGTCAGTTTGCTGTAGGGAGTGAGAGGTTGAATTTAGCCATTAAAAGCATTGAAGATGAGCTCGC
TTTAAGGTTGAAATTTTTTAAAGAGCAGGATAAAATGCTTGAATACAACCGCCTCAAACAACGCACCGAGCATGATTTAG
AAATGATTAGCACGACCGGTGTGTGTAAGGGCATTGAAAATTACGCGCGCCATTTCACCGGTAAAGCCCCTAATGAAACG
CCTTTTTGTTTGTTTGATTATTTAGGGATTTTTGAGCGGGAGTTTTTAGTCATTGTAGATGAAAGCCATGTGAGTTTGCC
GCAGTTTGGGGGGATGTATGCAGGGGATATGAGCAGGAAAAGCGTTTTAGTGGAATATGGTTTTAGATTGCCTAGCGCTT
TAGACAACCGCCCTTTAAAATTTGATGAATTTATCCATAAAAATTGCCAGTTCCTTTTTGTGTCCGCTACGCCCAATAAG
CTAGAATTAGAGCTTTCCAAAAAGAATGTCGCTGAGCAAATCATTCGCCCTACAGGGCTTTTAGACCCTAAATTTGAAGT
GCGAGACAGCGATAAGCAAGTCCAGGATTTATTTGATGAAATCAAGTTAGTGGTGGCCAGAGATGAAAGGGTGCTCATCA
CCACGCTCACTAAAAAAATGGCAGAAGAATTGTGCAAATATTATGCTGAATGGGGCTTGAAAGCGCGTTACATGCATAGT
GAAATTGATGCGATTGAAAGGAACCACATCATCCGCTCTTTAAGGCTTAAGGAATTTGACATTTTAATAGGGATCAATCT
TTTAAGAGAAGGGCTGGATTTGCCTGAAGTCTCTTTAGTAGCGATCATGGATGCGGATAAAGAAGGGTTTTTAAGGAGTG
AGACAAGCCTCATTCAAGCCATGGGGCGAGCCGCTAGAAACGCTAATGGCAAGGTTTTATTATACGCTAAAAAAACCACT
CAAAGCATGCAAAAAGCCTTTGAGATTACGAGTTACAGGCGCGCTAAGCAAGAAGAGTTCAATAAAATCCATAATATCAC
CCCTAAAACCGTTACTCGCGCTTTAGAAGAGGAGTTGAAATTAAGAGACGATGAGATTAGAATCGCTAAAGCTTTAAAAA
AGGACAAAATCCCTAAAAGCGAAAGGGAAAAAATCATTAAAGAACTGGATAAAAAAATGCGAGAATGCGCGAAAAATTTG
GACTTTGAAGAAGCGATGCGTTTGAGAGACGAAATCGCTAAATTAAGAACGCTTTAA

Domains

Predicted by InterProScan.

Type III restriction enzyme, res subunit (ResIII)

(15-137)

UvrB/uvrC motif (UVR)

(623-657)

UvrB interaction domain (UvrB_inter)

(159-248)

Helicase conserved C-terminal domain (Helicase_C)

(445-547)

Ultra-violet resistance protein B (UvrB)

(554-595)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

49.321

100

0.497
  uvrB Streptococcus pneumoniae TIGR4

49.321

100

0.497
  uvrB Streptococcus pneumoniae D39

49.321

100

0.497